Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Harriet Nilsson"'
Autor:
Axel Abelein, Jan Johansson, Xueying Zhong, Gefei Chen, Axel Leppert, Henrik Biverstål, Hans Hebert, Yuniesky Andrade-Talavera, Per Nilsson, Michael Landreh, Simone Tambaro, André Fisahn, Harriet Nilsson
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
Molecular chaperones play important roles in preventing protein misfolding and its potentially harmful consequences. Deterioration of molecular chaperone systems upon ageing are thought to underlie age-related neurodegenerative diseases, and augmenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf17819676c2ce84fffec37cb8965bf3
http://link.springer.com/article/10.1038/s42003-020-0757-z
http://link.springer.com/article/10.1038/s42003-020-0757-z
Autor:
Hans Hebert, Jan Johansson, Margit Kaldmäe, Axel Leppert, Helene Tigro, Gefei Chen, Harriet Nilsson, Xueying Zhong, Helen Poska
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Molecular chaperones assist proteins in achieving a functional structure and prevent them from misfolding into aggregates, including disease-associated deposits. The BRICHOS domain from familial dementia associated protein Bri2 (or ITM2B) probably ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9259b72a00faec599b805a6a3188ae1f
https://pubmed.ncbi.nlm.nih.gov/32555390
https://pubmed.ncbi.nlm.nih.gov/32555390
Autor:
Martin Paucar, Anca Dragomir, Tie-Qiang Li, Harriet Nilsson, Elisabet Einarsdottir, Juha Kere, Anna Lindstrand, Tobias Granberg, Hans Matsson, Andrea Bieder, Jesper Eisfeldt, Isabel Tapia-Páez
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
BackgroundDevelopmental dyslexia (DD) is a neurodevelopmental learning disorder with high heritability. A number of candidate susceptibility genes have been identified, some of which are linked to the function of the cilium, an organelle regulating l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb27fa8c2ee5534f56ea5996d8e28c4
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-413235
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-413235
Autor:
Yolanda Hedberg, Harriet Nilsson, Cristina Chircov, Xueying Zhong, Per M. Claesson, Thomas Crouzier, Benjamin Winkeljann, Hongji Yan, Oliver Lieleg, Illia Dobryden
Publikováno v:
Langmuir. 34:13615-13625
Mucins are high molar mass glycoproteins that assume an extended conformation and can assemble into mucus hydrogels that protect our mucosal epithelium. In nature, the challenging task of generating a mucus layer, several hundreds of micrometers in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9c1f49047e6f9ef677c63f8d3be37f
https://doi.org/10.1021/acs.langmuir.8b02190
https://doi.org/10.1021/acs.langmuir.8b02190
Autor:
Philip J.B. Koeck, Jan Johansson, Axel Abelein, Jenny Presto, Henrik Biverstål, Lovisa Hemmingsson, Gefei Chen, Michael Landreh, André Fisahn, Yuniesky Andrade-Talavera, Harriet Nilsson, Firoz Roshan, Axel Leppert, Simone Tambaro, Hans Hebert
Publikováno v:
Nature communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Protein misfolding and aggregation is increasingly being recognized as a cause of disease. In Alzheimer’s disease the amyloid-β peptide (Aβ) misfolds into neurotoxic oligomers and assembles into amyloid fibrils. The Bri2 protein associated with F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829f0ab337a4140dd23d2bb9e83b51e0
Autor:
Philip J.B. Koeck, Elisabeth Thomsson, Malin Bäckström, Hans Hebert, Harriet Nilsson, Daniel Ambort, Gunnar C. Hansson
Publikováno v:
Journal of Molecular Biology. 426(14):2567-2579
MUC2 is the major gel-forming mucin of the colon forming a protective gel barrier organized into an inner stratified and an outer loose layer. The MUC2 N-terminus (D1-D2-D′D3 domains) has a dual function in building a net-like structure by disulfid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e709303012d00c08136a9264ba66894
Autor:
Daniel Ambort, Gunnar C. Hansson, Hans Hebert, Malin E. V. Johansson, Philip J.B. Koeck, Harriet Nilsson, Anna Ermund, Bengt R. Johansson, Jenny K. Gustafsson
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5645-5650
MUC2, the major colonic mucin, forms large polymers by N-terminal trimerization and C-terminal dimerization. Although the assembly process for MUC2 is established, it is not known how MUC2 is packed in the regulated secretory granulae of the goblet c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf200dc5405c292170c8ab6d06cae44
https://doi.org/10.1073/pnas.1120269109
https://doi.org/10.1073/pnas.1120269109
Publikováno v:
Cell and Tissue Research. 330:257-269
Inhalation of hyperosmotic solutions (salt, mannitol) has been used in the treatment of patients with cystic fibrosis or asthma, but the mechanism behind the effect of hyperosmotic solutions is unclear. The relation between osmolarity and permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61814074ec631e8d553ebf60d082c94
https://doi.org/10.1007/s00441-007-0482-7
https://doi.org/10.1007/s00441-007-0482-7
Publikováno v:
Microscopy Research and Technique. 69:776-783
Ionic lanthanum is commonly used to trace permeability pathways across epithelia and endothelia in biological electron microscopy. A method for obtaining a uniformly dense precipitate of lanthanum is described. The method, which is a modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b3b287cc9381488ef94ad72bf8d2cd
https://doi.org/10.1002/jemt.20347
https://doi.org/10.1002/jemt.20347
Publikováno v:
Cellular Physiology and Biochemistry. 17:13-20
The ionic composition of the fluid lining the airways (airway surface liquid, ASL) in healthy subjects and patients with cystic fibrosis (CF) has been a matter of controversy. It has been attempted to resolve conflicting theories by using cell cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700db24da850133f0d45a049a13d96d3
https://doi.org/10.1159/000091455
https://doi.org/10.1159/000091455