Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Harriet E. Gee"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-14 (2020)
Abstract Radiotherapy is the cornerstone of treatment of high-grade gliomas (HGGs). It eradicates tumor cells by inducing oxidative stress and subsequent DNA damage. Unfortunately, almost all HGGs recur locally within several months secondary to radi
Externí odkaz:
https://doaj.org/article/f06b6a4a313349798b35ae2296443639
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment resistance remains a clinical problem. There have been recent advances in understanding the molecular mechanisms of radiation-induced cell death. The type of ce
Externí odkaz:
https://doaj.org/article/2b670b78731a4ce2ace0713a60cc3933
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9f98530e31300fe125ac252f05b19
https://doi.org/10.1158/0008-5472.22417851
https://doi.org/10.1158/0008-5472.22417851
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Supplementary Tables 1-6 Supp. Table 1: Clinicopathological characteristics of breast cancer patients whose tumours were profiled by miRNA expression microarrays to identify miRNAs associated with local relapse following radiotherapy. Supp. Table 2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f951d92c4452a370f5c128e23ffa4fa
https://doi.org/10.1158/0008-5472.22417845
https://doi.org/10.1158/0008-5472.22417845
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26eaaad942be250caced776fa8fee5
https://doi.org/10.1158/0008-5472.c.6509961
https://doi.org/10.1158/0008-5472.c.6509961
Autor:
Jiannis Ragoussis, Adrian L. Harris, Marian Taylor, Helen Sheldon, Harriet E. Gee, Cameron E. Snell, Laura Winchester, Carme Camps, Francesca M. Buffa
PDF file - 63K, Cox analysis including microRNA processing genes and single prognostic microRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4a8defe04d8a902356fdde957b3ade
https://doi.org/10.1158/0008-5472.22389500.v1
https://doi.org/10.1158/0008-5472.22389500.v1
Autor:
Jiannis Ragoussis, Adrian L. Harris, Marian Taylor, Helen Sheldon, Harriet E. Gee, Cameron E. Snell, Laura Winchester, Carme Camps, Francesca M. Buffa
PDF file - 58K, Cox analysis including microRNA processing genes and single prognostic microRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404127903cda24c1742f42b6e9f6086d
https://doi.org/10.1158/0008-5472.22389479.v1
https://doi.org/10.1158/0008-5472.22389479.v1
Autor:
Jiannis Ragoussis, Adrian L. Harris, Marian Taylor, Helen Sheldon, Harriet E. Gee, Cameron E. Snell, Laura Winchester, Carme Camps, Francesca M. Buffa
PDF file - 239K, Penalized Cox regression to identify microRNAs independent prognostic of distant relapse-free survival(DRFS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6219d53bf9f0a58dc0024480730e568c
https://doi.org/10.1158/0008-5472.22389509
https://doi.org/10.1158/0008-5472.22389509
Autor:
Jiannis Ragoussis, Adrian L. Harris, Marian Taylor, Helen Sheldon, Harriet E. Gee, Cameron E. Snell, Laura Winchester, Carme Camps, Francesca M. Buffa
PDF file 48K, The datasets used in the meta-analyses in Table 1 and Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8dcc7831bcfe27f87498af8b44d4ea
https://doi.org/10.1158/0008-5472.22389488.v1
https://doi.org/10.1158/0008-5472.22389488.v1
Autor:
Jiannis Ragoussis, Adrian L. Harris, Marian Taylor, Helen Sheldon, Harriet E. Gee, Cameron E. Snell, Laura Winchester, Carme Camps, Francesca M. Buffa
PDF file - 89K, Survival analysis of microRNA clusters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba3eadc7eb69354a0bfe086e0771933
https://doi.org/10.1158/0008-5472.22389485.v1
https://doi.org/10.1158/0008-5472.22389485.v1