Výsledky vyhledávání - "Harries, M H"

SB-272183, a selective 5-HT1A, 5-HT1B and 5-HT1D receptor antagonist in native tissue

Autor: Watson, J, Roberts, C, Scott, C, Kendall, I, Collin, L, Day, N C, Harries, M H, Soffin, E, Davies, C H, Randall, A D, Heightman, T, Gaster, L, Wyman, P, Parker, C, Price, G W, Middlemiss, D N

A novel compound, SB-272183 (5-Chloro-2, 3-dihydro-6-[4-methylpiperazin-1-yl]-1[4-pyridin-4-yl]napth-1-ylaminocarbonyl]-1H-indole), has been shown to have high affinity for human 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptors with pK(i) values of 8.0, 8.1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::747aab8b5e8e546c3560c0730740b0ac
https://europepmc.org/articles/PMC1572841/

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The profile of sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, in the marmoset

Autor: Harries, M H, Samson, N A, Cilia, J, Hunter, A J

1. Sabcomeline (SB-202026, 0.03 mg kg(-1), p.o.), a potent and functionally selective M1 receptor partial agonist, caused a statistically significant improvement in the performance of a visual object discrimination task by marmosets. No such improvem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57de9b3cafdfa70702905c3cc0347b30
https://europepmc.org/articles/PMC1565397/

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Effect of SB-205384 on the decay of GABA-activated chloride currents in granule cells cultured from rat cerebellum

Autor: Meadows, H J, Harries, M H, Thompson, M, Benham, C D

1. 4-Amino-7-hydroxy-2-methyl-5,6,7,8,-tetrahydrobenzo[b]thieno[2,3-b]pyrid ine-3-carboxylic acid, but-2-ynyl ester (SB-205384) and other gamma-aminobutyric acid(A) (GABA(A)) receptor modulators were tested for their effects on GABA-activated chlorid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d833188058002f9f5a5f7abc61b6ecaa
https://europepmc.org/articles/PMC1564816/

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