Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harrie Straatman"'
Autor:
Jan Brummund, Andreas Vogel, Sebastian Bartsch, Harrie Straatman, Sabrina Köpke, Martin Schürmann
Publikováno v:
Biotechnology journal. 15(11)
Alcohol dehydrogenases (ADH) are widely used to enantioselectively reduce ketones to chiral alcohols, but their application in industrial scale oxidations is rare. Reasons are the need for an NAD(P)+ cofactor regeneration system, often low performanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9c3f62049bac7bb825535e5e72b866
https://pubmed.ncbi.nlm.nih.gov/32846049
https://pubmed.ncbi.nlm.nih.gov/32846049
Autor:
Peter W. Sutton, Jan Brummund, Gregorio Álvaro, Harrie Straatman, Marina Guillén, Miquel García-Bofill, Martin Schürmann
Publikováno v:
Applied Catalysis A: General. 610:117934
Vanilla is the second most expensive spice in the world. This issue triggered the necessity to obtain its flavour compound, vanillin, by alternative methods, most of which have focused on biosynthesis since it can be labelled as “natural” and sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::854efcdceace1c435829c658a4d26aa1
https://doi.org/10.1016/j.apcata.2020.117934
https://doi.org/10.1016/j.apcata.2020.117934
Autor:
Harrie Straatman, Thomas Schmitges, Daniel Mink, Martin Schürmann, Iwona Kaluzna, Dennis van Tegelen, Monika Müller
Publikováno v:
Organic Process Research & Development. 20:814-819
The development of P450 platform technology has enabled the sustainable production of an oxygenated intermediate, 4-hydroxy-α-isophorone, on kilogram scale. Application of a cytochrome P450 enzyme resulted in an unprecedented product concentration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76cd9983ee49cb4ba4dc2074877ad122
https://doi.org/10.1021/acs.oprd.5b00282
https://doi.org/10.1021/acs.oprd.5b00282
Autor:
Harrie Straatman, Christopher John Squire, Michael David Golden, Daniel Mink, Andrew S. Wells, Rebecca E. Meadows, Elise Meulenbroeks, Martin Schürmann, Oliver May, Keith R. Mulholland, Hans Kierkels
Publikováno v:
Organic Process Research & Development. 17:1117-1122
Screening of 60 transaminases using three different amine donors found that the ω-transaminase from Vibrio fluvialis together with (S)-α-methylbenzylamine to be the most promising combination to deliver the desired (S)-1-(5-fluoropyrimidin-2-yl)-et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00c36999ee6d956fdeaa05c32807b55e
https://doi.org/10.1021/op400131h
https://doi.org/10.1021/op400131h
Autor:
Daniel Mink, Christopher John Squire, Andrew S. Wells, Rebecca E. Meadows, Michael David Golden, Hans Kierkels, Oliver May, Keith R. Mulholland, Harrie Straatman, Elise Meulenbroeks, Martin Schürmann
Publikováno v:
Practical Methods for Biocatalysis and Biotransformations 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7746755d41c98226d9b75c7c6331d69a
https://doi.org/10.1002/9781118697856.ch09
https://doi.org/10.1002/9781118697856.ch09
Autor:
Harrie Straatman, Jeroen A. F. Boogers, Laurent Lefort, André H.M. de Vries, Johannes G. de Vries, John Janssen, Robert Jan Vijn, Thijs Kuilman
Publikováno v:
Organic Process Research & Development, 14(3), 568-573. AMER CHEMICAL SOC INC
High throughput screening was used to find a cost-effective and scalable catalyst for the asymmetric hydrogenation of a sterically demanding enamide as an intermediate towards a new potent melanocortin receptor agonist useful in the treatment of obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717024efac08679bf65f1e42bea3cbb5
https://research.rug.nl/en/publications/d6615bcc-d3b2-4d98-a222-9a4dc9ca34c3
https://research.rug.nl/en/publications/d6615bcc-d3b2-4d98-a222-9a4dc9ca34c3
Autor:
Harrie Straatman, David J. Ager, Jared W. Fennell, John Arnold Werner, Johannes G. de Vries, Kevin A. Sullivan, Mark D. Argentine, Natascha Sereinig, Todd D. Maloney, Roger B. Scherer, Laurent Lefort
Publikováno v:
Catalysis Science & Technology. 2:2077
A key step towards a highly-selective antagonist of ionotropic glutamate receptors entails the diastereoselective arene hydrogenation of an enantiopure tetrahydroisoquinoline. An extensive screen using parallel reactors was conducted and led to the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e4d8fe2c15c81926276f632836ebbf3
https://doi.org/10.1039/c2cy20251d
https://doi.org/10.1039/c2cy20251d
Autor:
Bartsch, Sebastian, Brummund, Jan, Köpke, Sabrina, Straatman, Harrie, Vogel, Andreas, Schürmann, Martin
Publikováno v:
Biotechnology Journal; Nov2020, Vol. 15 Issue 11, p1-13, 13p
Publikováno v:
Practical Methods for Biocatalysis & Biotransformations 3; 2016, pi-xxvi, 26p
Publikováno v:
Practical Methods for Biocatalysis & Biotransformations 3; 2016, p253-284, 32p