Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde.

Autor: Espiritu MJ; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Chen J; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Yadav J; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Larkin M; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Pelletier RD; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Chan JM; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Gc JB; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Natesan S; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.)., Harrelson JP; School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (M.J.E., M.L., J.P.H.); College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington (J.C., J.B.G., S.N.); Amgen, Cambridge, Massachusetts (J.Y.); Department of Medicinal Chemistry, University of Washington, Seattle, Washington (R.D.P.); and Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.M.C.) harrelsonj@pacificu.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2020 Oct; Vol. 48 (10), pp. 1028-1043. Date of Electronic Publication: 2020 Aug 12.

Forecasting academic success through implementation of an online prerequisite review tutorials program for first year pharmacy students.

Autor: Stamper BD; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: stamperb@pacificu.edu., Buhler AV; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: abuhler@pacificu.edu., Harrelson JP; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: harrelsonj@pacificu.edu., Roberts SC; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: sroberts@pacificu.edu., Malhotra A; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: ashim.malhotra@pacificu.edu., Elbarbry FA; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: fawzy.elbarbry@pacificu.edu., Rao D; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: deeparao@pacificu.edu., Karimi R; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: karimir@pacificu.edu., Turner RB; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: brigg.turner@pacificu.edu., Marlow C; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: cmarlow@pacificu.edu., Devaud LL; Pacific University School of Pharmacy, Hillsboro, OR 97123. Electronic address: devaudl@pacificu.edu.

Publikováno v: Currents in pharmacy teaching & learning [Curr Pharm Teach Learn] 2017 Mar - Apr; Vol. 9 (2), pp. 261-271. Date of Electronic Publication: 2017 Feb 01.

Inactivation of CYP2A6 by the Dietary Phenylpropanoid trans-Cinnamic Aldehyde (Cinnamaldehyde) and Estimation of Interactions with Nicotine and Letrozole.

Autor: Chan J; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Oshiro T; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Thomas S; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Higa A; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Black S; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Todorovic A; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Elbarbry F; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.)., Harrelson JP; Chemistry Department, Pacific University Oregon, Forest Grove, Oregon (J.C., T.O., A.H., S.B.); and School of Pharmacy, Pacific University Oregon, Hillsboro, Oregon (S.T., A.H., S.B., A.T., F.E., J.P.H.) harrelsonj@pacificu.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2016 Apr; Vol. 44 (4), pp. 534-43. Date of Electronic Publication: 2016 Feb 05.

Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen.

Autor: Harrelson JP; School of Pharmacy, Pacific University Oregon, 222 S.E. 8th Ave., Ste. 451, Hillsboro, OR 97123, USA. harrelsonj@pacificu.edu, Stamper BD, Chapman JD, Goodlett DR, Nelson SD

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2012 Aug; Vol. 40 (8), pp. 1460-5. Date of Electronic Publication: 2012 May 21.

Prediction of CYP3A-mediated drug-drug interactions using human hepatocytes suspended in human plasma.

Autor: Mao J; Department of Drug Disposition, Eli Lilly and Co. Lilly Corporate Center, Indianapolis, IN 46285, USA. mao_jialin@lilly.com, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2011 Apr; Vol. 39 (4), pp. 591-602. Date of Electronic Publication: 2011 Jan 06.