Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development.

Autor: Bresciani E; Oncogenesis and Development Section., Carrington B; Zebrafish Core., Yu K; Oncogenesis and Development Section., Kim EM; Oncogenesis and Development Section., Zhen T; Oncogenesis and Development Section., Guzman VS; Oncogenesis and Development Section., Broadbridge E; Oncogenesis and Development Section., Bishop K; Zebrafish Core., Kirby M; Flow Cytometry Core., Harper U; Genomics Core., Wincovitch S; Cytogenetics and Microscopy Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Dell'Orso S; Next Generation Sequencing Unit, Office of Science and Technology., Sartorelli V; Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD., Sood R; Oncogenesis and Development Section.; Zebrafish Core., Liu P; Oncogenesis and Development Section.

Publikováno v: Blood advances [Blood Adv] 2021 Dec 14; Vol. 5 (23), pp. 4949-4962.

Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease

Autor: Velez, J I, Chandrasekharappa, S C, Henao, E, Martinez, A F, Harper, U, Jones, M, Solomon, B D, Lopez, L, Garcia, G, Aguirre-Acevedo, D C, Acosta-Baena, N, Correa, J C, Lopera-Gomez, C M, Jaramillo-Elorza, M C, Rivera, D, Kosik, K S, Schork, N J, Swanson, J M, Lopera, F, Arcos-Burgos, M

Publikováno v: Velez, J I; Chandrasekharappa, S C; Henao, E; Martinez, A F; Harper, U; Jones, M; et al.(2012). Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. Molecular Psychiatry, 18(5), 568-575. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/5fh7v0wm

The literature on GWAS (genome-wide association studies) data suggests that very large sample sizes (for example, 50,000 cases and 50,000 controls) may be required to detect significant associations of genomic regions for complex disorders such as Al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::779d461cc245b6056f08bb75eaaa892f
http://www.escholarship.org/uc/item/5fh7v0wm

Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility.

Autor: Ramanagoudr-Bhojappa R; Cancer Genomics Unit, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Carrington B; Zebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Ramaswami M; Cancer Genomics Unit, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Bishop K; Zebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Robbins GM; Zebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Jones M; Genomics Core, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Harper U; Genomics Core, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Frederickson SC; Zebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Kimble DC; Cancer Genomics Unit, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Sood R; Zebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Chandrasekharappa SC; Cancer Genomics Unit, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Genomics Core, Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2018 Dec 12; Vol. 14 (12), pp. e1007821. Date of Electronic Publication: 2018 Dec 12 (Print Publication: 2018).

Vitamin B 12 Ameliorates Pesticide-Induced Sociability Impairment in Zebrafish (Danio rerio): A Prospective Controlled Intervention Study.

Autor: Robea, Madalina Andreea¹ (AUTHOR) madalina.robea11@gmail.com, Ilie, Ovidiu Dumitru² (AUTHOR) ovidiuilie90@yahoo.com, Nicoara, Mircea Nicusor^3,4 (AUTHOR) alin.ciobica@uaic.ro, Solcan, Gheorghe⁵ (AUTHOR) gsolcan@yahoo.com, Romila, Laura Ecaterina⁶ (AUTHOR) laura_ekaa@yahoo.com, Ureche, Dorel⁷ (AUTHOR) mirmag@uaic.ro, Ciobica, Alin^3,8,9 (AUTHOR)

Publikováno v: Animals (2076-2615). Feb2024, Vol. 14 Issue 3, p405. 19p.

Paternal or Maternal Uniparental Disomy of Chromosome 16 Resulting in Homozygosity of a Mutant Allele Causes Fanconi Anemia.

Autor: Donovan FX; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Kimble DC; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Kim Y; Laboratory of Genome Maintenance, The Rockefeller University, New York, New York., Lach FP; Laboratory of Genome Maintenance, The Rockefeller University, New York, New York., Harper U; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Kamat A; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Jones M; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Sanborn EM; Laboratory of Genome Maintenance, The Rockefeller University, New York, New York., Tryon R; Blood and Marrow Transplant Program, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota., Wagner JE; Blood and Marrow Transplant Program, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota., MacMillan ML; Blood and Marrow Transplant Program, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota., Ostrander EA; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland., Auerbach AD; Human Genetics and Hematology Program, The Rockefeller University, New York, New York., Smogorzewska A; Laboratory of Genome Maintenance, The Rockefeller University, New York, New York., Chandrasekharappa SC; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland.

Publikováno v: Human mutation [Hum Mutat] 2016 May; Vol. 37 (5), pp. 465-8. Date of Electronic Publication: 2016 Feb 23.