Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Harold Walder"'
Autor:
Mark Oldham, Paul Yoon, Zak Fathi, Wayne F Beyer, Justus Adamson, Leihua Liu, David Alcorta, Wenle Xia, Takuya Osada, Congxiao Liu, Xiao Y Yang, Rebecca D Dodd, James E Herndon, Boyu Meng, David G Kirsch, H Kim Lyerly, Mark W Dewhirst, Peter Fecci, Harold Walder, Neil L Spector
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162078 (2016)
This work investigates X-PACT (X-ray Psoralen Activated Cancer Therapy): a new approach for the treatment of solid cancer. X-PACT utilizes psoralen, a potent anti-cancer therapeutic with current application to proliferative disease and extracorporeal
Externí odkaz:
https://doaj.org/article/7f8a822b29f64920acbd0e793ca8a94f
Autor:
Wenle Xia, David Gooden, Leihua Liu, Sumin Zhao, Erik J Soderblom, Eric J Toone, Wayne F Beyer, Harold Walder, Neil L Spector
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88983 (2014)
Photo-activation of psoralen with UVA irradiation, referred to as PUVA, is used in the treatment of proliferative skin disorders. The anti-proliferative effects of PUVA have been largely attributed to psoralen intercalation of DNA, which upon UV trea
Externí odkaz:
https://doaj.org/article/1d28ff245e1449448ba258d2b2a9f600
Autor:
Harold Walder, Diane Renee Fels, Wayne F. Beyer, Katherine S. Hansen, Alexandru D. Buhimschi, Francis P. Gasparro, Hongwu Jing, David M. Gooden, Mark W. Dewhirst
Publikováno v:
Photochemistry and photobiology, vol 96, iss 5
Photochem Photobiol
Photochem Photobiol
Psoralen is a furocoumarin natural product that intercalates within DNA and forms covalent adducts when activated by ultraviolet radiation. It is well known that this property contributes to psoralen's clinical efficacy in several disease contexts, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afcf67789fff01d171ee95aff1a133f
https://escholarship.org/uc/item/7tk517vc
https://escholarship.org/uc/item/7tk517vc
Autor:
Harold Walder, Justus Adamson, Boyu Meng, Mark Oldham, Tracy L. Gieger, D Miles, Stewart Mein, Suk W. Yoon, Neil L. Spector, Michael W. Nolan, Wayne F. Beyer, Zak Fathi, R. M. Gunasingha
Publikováno v:
Biomedical Physics & Engineering Express. 3:035018
Autor:
Neil L. Spector, Sumin Zhao, Wayne F. Beyer, Eric J. Toone, Wenle Xia, Erik J. Soderblom, David M. Gooden, Harold Walder, Leihua Liu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e88983 (2014)
PLoS ONE, Vol 9, Iss 2, p e88983 (2014)
Photo-activation of psoralen with UVA irradiation, referred to as PUVA, is used in the treatment of proliferative skin disorders. The anti-proliferative effects of PUVA have been largely attributed to psoralen intercalation of DNA, which upon UV trea
Autor:
Zakaryae Fathi, Mark W. Dewhirst, Mark Oldham, Peter E. Fecci, Harold Walder, Justus Adamson, Wayne F. Beyer, David A. Alcorta, Takuya Osada, Kim Lyerly, Boyu Meng, Sora C. Yoon, Neil L. Spector
Publikováno v:
Medical Physics. 43:3823-3823
Purpose: This work investigates X-PACT (X-ray Psoralen Activated Cancer Therapy): a new approach for the treatment of cancer. X-PACT utilizes psoralen, a potent anti-cancer therapeutic with immunogenic anti-cancer potential. Psoralen therapies have b
Autor:
Adam B. Sumlin, Adaffaras Adal, Zale P. Bernstein, James L. Kepner, Carleton C. Stewart, Sandra O. Gollnick, Harold Walder, Thomas J. Dougherty, Supriya D. Mahajan, Bernard J. Poiesz, Paul K. Wallace, Stanley A. Schwartz
Publikováno v:
Current HIV research. 6(2)
An ex vivo trial utilizing photopheresis with Benzoporphyrin Derivative as the photoactive compound, identified the minimum energy levels of light and concentrations of BPD that eradicated both cell-free and cell-associated HIV-1 infectivity without
Autor:
Wayne F. Beyer, Paul Yoon, Leihua Liu, Harold Walder, Mark Oldham, Michael W. Nolan, Zakaryae Fathi, Neil L. Spector, Justus Adamson, David A. Alcorta, T Gieger
Publikováno v:
Medical Physics. 42:3352-3352
Purpose: Psoralen is a UV-light activated anti-cancer biotherapeutic used for treating skin lesions (PUVA) and advanced cutaneous T-cell lymphoma (ECP). To date psoralen has not been used to treat deep seated tumors due to difficulty in generating UV
Autor:
Supriya D. Mahajan, Sandra O. Gollnick, Harold Walder, Carleton C. Stewart, Bernard J. Poiesz, Paul K. Wallace, James L. Kepner, Adam B. Sumlin, Zale P. Bernstein, Thomas J. Dougherty, Stanley A. Schwartz
Publikováno v:
Blood. 110:2275-2275
An ex vivo trial utilizing photopheresis with Benzoporphyrin Derivative as the photoactive compound, identified the minimum energy levels of light and concentrations of BPD that eradicated both cell-free and cell-associated HIV-1 infectivity without
Autor:
Thomas J. Dougherty, Zale P. Bernstein, Supriya D. Mahajan, Adam B. Sumlin, Stanley A. Schwartz, Carleton C. Stewart, Sandra O. Gollnick, Harold Walder, Madhavan Nair, Bernard J. Poiesz
Publikováno v:
Blood. 108:1257-1257
HIV is able to elude both cellular and humoral arms of the immune system; thereby making viral control difficult. Extra corporeal photochemotherapy (ECP) or photopheresis is an immunomodulatory therapy in which lymphocytes are reinfused into the host