Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Harold Shlevin"'
Autor:
William L Redmond, Yoshinobu Koguchi, Annah S Rolig, Noriko Iwamoto, Takashi Shimada, Elizabeth R Sturgill, Zhaoyu Sun, Venkatesh Rajamanickam, Brady Bernard, Peter G Traber, Eliezer Zomer, J Rex Horton, Harold Shlevin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background PD-1/PD-L1 engagement and overexpression of galectin-3 (Gal-3) are critical mechanisms of tumor-induced immune suppression that contribute to immunotherapy resistance. We hypothesized that Gal-3 blockade with belapectin (GR-MD-02) plus ant
Externí odkaz:
https://doaj.org/article/b74b3ece4a084cb7ac2ccf373351e2ec
Autor:
Elizabeth R. Sturgill, Annah S. Rolig, Stefanie N. Linch, Courtney Mick, Melissa J. Kasiewicz, Zhaoyu Sun, Peter G. Traber, Harold Shlevin, William L. Redmond
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Treatment with an agonist anti-OX40 antibody (aOX40) boosts anti-tumor immunity by providing costimulation and driving effector T cell responses. However, tumor-induced immune suppression contributes significantly to poor response rates to aOX40 ther
Externí odkaz:
https://doaj.org/article/161b14a5b58c4b3baa656311843a52b3
Autor:
Mazen Noureddin, Zachary Goodman, Dean Tai, Elaine L. K. Chng, Yayun Ren, Pol Boudes, Harold Shlevin, Guadalupe Garcia‐Tsao, Stephen A. Harrison, Naga P. Chalasani
Publikováno v:
Alimentary Pharmacology & Therapeutics. 57:409-417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f5d9da25fda25ea9f5291b03641654
https://doi.org/10.1111/apt.17363
https://doi.org/10.1111/apt.17363
Autor:
Mazen Noureddin, Dean Tai, Elaine Chng, Yayun Ren, Pol Boudes, Harold Shlevin, Stephen Harrison, Guadalupe Garcia-Tsao, Zachary Goodman, Naga Chalasani
Publikováno v:
Journal of Hepatology. 77:S623-S624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f648a5b3d5ec14c4fa8e4c9c5697cec
https://doi.org/10.1016/s0168-8278(22)01564-1
https://doi.org/10.1016/s0168-8278(22)01564-1
Autor:
Mazen Noureddin, Dean Tai, Elaine Chng, Yayun Ren, Pol Boudes, Harold Shlevin, Stephen Harrison, Guadalupe Garcia-Tsao, Naga Chalasani, Zachary Goodman
Publikováno v:
Journal of Hepatology. 77:S619-S620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a2871d1ce6516483f0ec5da7373c79
https://doi.org/10.1016/s0168-8278(22)01557-4
https://doi.org/10.1016/s0168-8278(22)01557-4
Autor:
Yaping Wu, Brendan D. Curti, Zhaoyu Sun, William L. Redmond, Brady Bernard, Christopher B. Fountain, Peter G. Traber, Takashi Shimada, Yoshinobu Koguchi, Rom Leidner, Eliezer Zomer, Elizabeth Sturgill, George Morris, Venkatesh Rajamanickam, Noriko Iwamoto, Annah S Rolig, Ian Hilgart-Martiszus, J. Rex Horton, Shu Ching Chang, Harold Shlevin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundPD-1/PD-L1 engagement and overexpression of galectin-3 (Gal-3) are critical mechanisms of tumor-induced immune suppression that contribute to immunotherapy resistance. We hypothesized that Gal-3 blockade with belapectin (GR-MD-02) plus anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1c844347afeb00988b18adab8210ae
https://jitc.bmj.com/content/9/4/e002371.full
https://jitc.bmj.com/content/9/4/e002371.full
Autor:
Stefanie N. Linch, Harold Shlevin, Melissa J Kasiewicz, Annah S Rolig, William L. Redmond, Peter G. Traber, Elizabeth Sturgill, Zhaoyu Sun, Courtney Mick
Publikováno v:
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
Treatment with an agonist anti-OX40 antibody (aOX40) boosts anti-tumor immunity by providing costimulation and driving effector T cell responses. However, tumor-induced immune suppression contributes significantly to poor response rates to aOX40 ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a581525ac509ed20d0123981b59a8b3
https://doi.org/10.1080/2162402x.2021.1892265
https://doi.org/10.1080/2162402x.2021.1892265
Autor:
Naga Chalasani, G. Mani Subramanian, Adam Allgood, Harold Shlevin, Eric S. Orman, Robert P. Myers, Hani Shamseddeen, Eduardo Vilar-Gomez
Publikováno v:
Drug Saf
BACKGROUND: Patients with cirrhosis may have spontaneous fluctuations in liver enzymes, which may confound detection of drug-induced liver injury (DILI), but these fluctuations have not been described. OBJECTIVE: We sought to quantify spontaneous liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963509b7f1c06bf235f9de942c3a6d9f
https://europepmc.org/articles/PMC7050367/
https://europepmc.org/articles/PMC7050367/
Autor:
Naga Chalasani, Manal F. Abdelmalek, Guadalupe Garcia-Tsao, Raj Vuppalanchi, Naim Alkhouri, Mary Rinella, Mazen Noureddin, Maxmillan Pyko, Mitchell Shiffman, Arun Sanyal, Adam Allgood, Harold Shlevin, Rex Horton, Eliezer Zomer, William Irish, Zachary Goodman, Stephen A. Harrison, Peter G. Traber, Manal Abdelmalek, Luis Balart, Brian Borg, Michael Charlton, Hari Conjeevaram, Michael Fuchs, Reem Ghalib, Pierre Gholam, Dina Halegoua-De Marzio, Stephen Harrison, Christopher Jue, Nyingi Kemmer, Kris Kowdley, Michelle Lai, Eric Lawitz, Rohit Loomba, Angelo Paredes, Don Rockey, Miguel Rodriguez, Raymond Rubin, Michael Ryan, Andrew Scanga, Thomas Sepe, Brent Tetri, Paul Thuluvath, Dawn Torres, John Vierling, Julia Wattacheril, Amanda Weiland, Donald Zogg
Publikováno v:
Gastroenterology. 158(5)
Background & Aims Increased levels of galectin 3 have been associated with nonalcoholic steatohepatitis (NASH) and contribute to toxin-induced liver fibrosis in mice. GR-MD-02 (belapectin) is an inhibitor of galectin 3 that reduces liver fibrosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ceabcdee7e0914cf6f4b79f06e59fe
https://pubmed.ncbi.nlm.nih.gov/31812510
https://pubmed.ncbi.nlm.nih.gov/31812510
Publikováno v:
Journal of the American Academy of Dermatology. 77:753-755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfceec177550c81c47f3b1fb1f107cf4
https://doi.org/10.1016/j.jaad.2017.05.055
https://doi.org/10.1016/j.jaad.2017.05.055