Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Harold S. Sacks"'
Autor:
Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Nathan C. Winn, Jaume Padilla, Marc Liesa, Harold S. Sacks, Orian S. Shirihai
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102087- (2021)
Beige adipocyte mitochondria contribute to thermogenesis by uncoupling and by ATP-consuming futile cycles. Since uncoupling may inhibit ATP synthesis, it is expected that expenditure through ATP synthesis is segregated to a disparate population of mi
Externí odkaz:
https://doaj.org/article/4b8e9dfe1be44446bb4a1b85629f27e1
Autor:
Thomas J. Jurrissen, Francisco I. Ramirez-Perez, Francisco J. Cabral-Amador, Rogerio N. Soares, Ryan J. Pettit-Mee, Edgar E. Betancourt-Cortes, Neil J. McMillan, Neekun Sharma, Helena N. M. Rocha, Shumpei Fujie, Mariana Morales-Quinones, Yoskaly Lazo-Fernandez, Andrew A. Butler, Subhashis Banerjee, Harold S. Sacks, Jamal A. Ibdah, Elizabeth J. Parks, R. Scott Rector, Camila Manrique-Acevedo, Luis A. Martinez-Lemus, Jaume Padilla
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H879-H891
Adropin is a peptide largely secreted by the liver and known to regulate energy homeostasis; however, it also exerts cardiovascular effects. Herein, we tested the hypothesis that low circulating levels of adropin in obesity and type 2 diabetes (T2D)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7064f696e54b677f7e59ffa567c26a2c
https://doi.org/10.1152/ajpheart.00385.2022
https://doi.org/10.1152/ajpheart.00385.2022
Autor:
Ian Bloor, Michael E. Symonds, Ksenija Velickovic, Harold S. Sacks, Virginie Sottile, Hilda Anaid Lugo Leija
Publikováno v:
Journal of Cellular and Molecular Medicine
Beige adipocytes possess the morphological and biochemical characteristics of brown adipocytes, including the mitochondrial uncoupling protein (UCP)1. Mesenchymal stem cells (MSCs) are somatic multipotent progenitors which differentiate into lipid‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f29d7446595d0581b028443f0f1e9c
https://doi.org/10.1111/jcmm.15749
https://doi.org/10.1111/jcmm.15749
Autor:
Anna Nagy, Elizabeth Zanley, Jennifer A. Tremmel, Yanqiu Song, Damini Dey, Tracey McLaughlin, Koen Nieman, Jack H. Boyd, Yue Xu, Harold S. Sacks, Ingela Schnittger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b35e0c8c0cde09bde5579c0d6f4fe5c
https://doi.org/10.1161/jaha.121.021003
https://doi.org/10.1161/jaha.121.021003
Autor:
James Law, Virginie Sottile, Ksenija Velickovic, Harold S. Sacks, David E. Morris, Helen Budge, Ian Bloor, Michael E. Symonds, Hilda Anaid Lugo Leija, Declan Wayne
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Brown adipose tissue (BAT) is able to rapidly generate heat and metabolise macronutrients, such as glucose and lipids, through activation of mitochondrial uncoupling protein 1 (UCP1). Diet can modulate UCP1 function but the capacity of individual nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a7b15a764516c8fd11b6b1039c68ca
http://link.springer.com/article/10.1038/s41598-019-45540-1
http://link.springer.com/article/10.1038/s41598-019-45540-1
Autor:
Orian S. Shirihai, Makenzie L Woodford, Rebeca Acín-Pérez, R. Scott Rector, Jill A. Kanaley, Nathan C. Winn, Victoria J. Vieira-Potter, Harold S. Sacks, Jaume Padilla, Sarah A. Hansen, Lolade A Ayedun, Megan M Haney
Publikováno v:
Diabetes
The prevailing dogma is that thermogenic brown adipose tissue (BAT) contributes to improvements in glucose homeostasis in obesogenic animal models, though much of the evidence supporting this premise is from thermostressed rodents. Determination of w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258c24b56b0e7271d55a81bafafa7ab3
https://doi.org/10.2337/db18-1070
https://doi.org/10.2337/db18-1070
Autor:
Michael E. Symonds, Amal Surrati, Ksenija Velickovic, Harold S. Sacks, Hilda Anaid Lugo Leija, Dong-Hyun Kim, Virginie Sottile
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 5, Pp 917-927 (2020)
Background/aims Glutamine is the most abundant amino acid in the body and has a metabolic role as a precursor for protein, amino sugar and nucleotide synthesis. After glucose, glutamine is the main source of energy in cells and has recently been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1b244212d29010469e131ae843830f
https://pubmed.ncbi.nlm.nih.gov/32946687
https://pubmed.ncbi.nlm.nih.gov/32946687
Autor:
Linsey Stiles, Sylviane Lagarrigue, Ilan Y. Benador, Anne N. Murphy, Gloria A. Benavides, Marc Liesa, Jonathan Wanagat, Georgios Karamanlidis, Laurent Vergnes, Orian S. Shirihai, Victor M. Darley-Usmar, Rebeca Acín-Pérez, Francesca Amati, Michaela Veliova, Arianne Caudal, Ajit S. Divakaruni, Rong Tian, Harold S. Sacks, Karen Reue, Anton Petcherski
Publikováno v:
The EMBO journal, vol 39, iss 13
The EMBO journal, vol. 39, no. 13, pp. e104073
The EMBO Journal
The EMBO journal, vol. 39, no. 13, pp. e104073
The EMBO Journal
Respirometry is the gold standard measurement of mitochondrial oxidative function, as it reflects the activity of the electron transport chain complexes working together. However, the requirement for freshly isolated mitochondria hinders the feasibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c0f6badb31cd697d71fe88a14ec025
https://escholarship.org/uc/item/3w97g9bj
https://escholarship.org/uc/item/3w97g9bj
Autor:
Michael E. Symonds, James Law, Helen Budge, Mark Pope, Peter Aldiss, Hernan P. Fainberg, Harold S. Sacks, Neele Dellschaft
Publikováno v:
Journal of Endocrinology. 238:R53-R62
Although brown adipose tissue (BAT) is one of the smallest organs in the body, it has the potential to have a substantial impact on both heat production as well as fat and carbohydrate metabolism. This is most apparent at birth, which is characterise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cc5e2a83a56a5abe1a3e78cbc3e729
https://doi.org/10.1530/joe-18-0084
https://doi.org/10.1530/joe-18-0084
Autor:
Harold S. Sacks, Mikaela L. McKenney-Drake, Mouhamad Alloosh, Rebecca S. Bruning, Stacey D. Rodenbeck, Kyle W. Yancey, Michael Sturek, Ayeeshik Kole
Publikováno v:
The Annals of Thoracic Surgery. 103:1622-1630
Background Pericoronary epicardial adipose tissue (cEAT) serves as a metabolic and paracrine organ that contributes to inflammation and is associated with macrovascular coronary artery disease (CAD) development. Although there is a strong correlation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb2e7fc165323247a605277417f0fe7
https://doi.org/10.1016/j.athoracsur.2016.11.034
https://doi.org/10.1016/j.athoracsur.2016.11.034