Zobrazeno 1 - 2
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pro vyhledávání: '"Harold Moloney"'
Autor:
Michael O. Frederick, Michael P. Carroll, Olivia Gowran, Mark A. Pietz, Michael M. Murray, Eoin M. Wilson, Harold Moloney, Aoibheann O’Connor, Douglas Patton Kjell, C. Brad Held
Publikováno v:
Organic Process Research & Development. 23:2549-2555
A new synthesis for an intermediate of abemaciclib is described. Keys to this route are the use of inexpensive starting materials, biphasic amine alkylation for mild C–N bond formation, anhydrous c...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f01182f898e21be872852c4af2b5ae9
https://doi.org/10.1021/acs.oprd.9b00347
https://doi.org/10.1021/acs.oprd.9b00347
Publikováno v:
The Journal of organic chemistry. 82(12)
An efficient three-step synthesis of a series of fused bicyclic s-[1,2,4]triazolo[1,5-a]pyridines 1 was accomplished utilizing novel intermediates derived from inexpensive, commercially available hydrazides A and methyl coumalate B. A significant fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69d02cd4012d4ef081265407d3ae83c
https://pubmed.ncbi.nlm.nih.gov/28494588
https://pubmed.ncbi.nlm.nih.gov/28494588