Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Harold M. McNamara"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Optogenetic tools can provide fine spatial and temporal control over many biological processes. Yet the development of new light-switchable protein variants remains challenging, and the field still lacks general approaches to engineering or
Externí odkaz:
https://doaj.org/article/b4e2ac9c372d43eea2bd320ea8fbd09b
Publikováno v:
Physical Review X, Vol 6, Iss 3, p 031001 (2016)
Complex electrical dynamics in excitable tissues occur throughout biology, but the roles of individual ion channels can be difficult to determine due to the complex nonlinear interactions in native tissue. Here, we ask whether we can engineer a tissu
Externí odkaz:
https://doaj.org/article/68a57f0e20a24f7f95fea12a60209b7b
Publikováno v:
Seminars in celldevelopmental biology.
Technological advances have driven many recent advances in developmental biology. Light sheet imaging can reveal single-cell dynamics in living three-dimensional tissues, whereas single-cell genomic methods open the door to a complete catalogue of ce
Autor:
Gloria Ortiz, Rajath Salegame, Adam E. Cohen, Haitan Xu, Ziad Al Tanoury, Shahinoor Begum, Olivier Pourquié, Harold M. McNamara
Publikováno v:
Nature physics
Electrical signaling in biology is typically associated with action potentials, transient spikes in membrane voltage that return to baseline. Hodgkin-Huxley and related conductance-based models of electrophysiology belong to a more general class of r
Autor:
Charlotte Fugier-Schmucker, Fanny Bousson, Aurore Hick-Colin, Fabio Marchiano, Daniel Sieiro, Ziad Al Tanoury, Jérome Chal, Harold M. McNamara, Erica Wagner, Rhonda Bassel-Duby, Kevin Kit Parker, Alejandra Rodríguez-delaRosa, Svetlana Gapon, Vandana Gupta, Olivier Pourquié, Jyoti Rao, Eric N. Olson, Thomas Cherrier, John F. Zimmerman, Alexander P. Nesmith, Bianca Habermann, Adam E. Cohen
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (28), pp.e2022960118. ⟨10.1073/pnas.2022960118⟩
International audience; Duchenne muscular dystrophy (DMD) is a devastating genetic disease leading to degeneration of skeletal muscles and premature death. How dystrophin absence leads to muscle wasting remains unclear. Here, we describe an optimized
Autor:
Olivier Pourquié, Gloria Ortiz, Rajath Salegame, Haitan Xu, Shahinoor Begum, Ziad Al Tanoury, Adam E. Cohen, Harold M. McNamara
Electrical signaling in biology is typically associated with action potentials, transient spikes in membrane voltage that return to baseline. The Hodgkin-Huxley equations of electrophysiology belong to a more general class of reaction-diffusion equat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c644275656cbdcc86c07e4b016e20d
https://doi.org/10.1101/570440
https://doi.org/10.1101/570440
Autor:
Haitan Xu, Ziad Al Tanoury, Rajath Salegame, Harold M. McNamara, Gloria Ortiz, Olivier Pourquié, Adam E. Cohen
Publikováno v:
Web of Science
Autor:
Adam E. Cohen, Stephanie Dodson, Harold M. McNamara, Björn Sandstede, Evan W. Miller, Yi-Lin Huang
Summary Little is known about how individual cells sense the macroscopic geometry of their tissue environment. Here, we explore whether long-range electrical signaling can convey information on tissue geometry to individual cells. First, we studied a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7652db87752a960fe4ef8f5ca1fd320
https://europepmc.org/articles/PMC6204347/
https://europepmc.org/articles/PMC6204347/
Autor:
Harold M. McNamara, Yi-Lin Huang, Stephanie Dodson, Björn Sandstede, Adam E. Cohen, Evan W. Miller
Little is known about how individual cells sense the macroscopic geometry of their tissue environment. Here we explore whether long-range electrical signaling can convey information on tissue geometry to influence electrical dynamics of individual ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093b89c2ef7e4d6f286cba2815100849
https://doi.org/10.1101/291617
https://doi.org/10.1101/291617
Autor:
Richard B. Reilly, Marian Tsanov, Omar Mamad, Karl Deisseroth, Lars Stumpp, Charu Ramakrishnan, Harold M. McNamara
Publikováno v:
PLoS Biology, Vol 15, Iss 9, p e2002365 (2017)
PLoS Biology
PLoS Biology
The hippocampus is the main locus of episodic memory formation and the neurons there encode the spatial map of the environment. Hippocampal place cells represent location, but their role in the learning of preferential location remains unclear. The h