Epigenetic predictors of maximum lifespan and other life history traits in mammals

Autor: Caesar Z. Li, Amin Haghani, Todd R. Robeck, Diego Villar, Ake T. Lu, Joshua Zhang, Chris G. Faulkes, Ha Vu, Julia Ablaeva, Danielle M. Adams, Reza Ardehali, Adriana Arneson, C. Scott Baker, Katherine Belov, Daniel T. Blumstein, Eleanor K. Bors, Charles E. Breeze, Robert T. Brooke, Janine L. Brown, Alex Caulton, Julie M. Cavin, Ioulia Chatzistamou, Hao Chen, Priscila Chiavellini, Oi-Wa Choi, Shannon Clarke, Joseph DeYoung, Candice K. Emmons, Stephan Emmrich, Zhe Fei, Steven H. Ferguson, Carrie J. Finno, Jennifer E. Flower, Jean-Michel Gaillard, Eva Garde, Vadim N. Gladyshev, Rodolfo G. Goya, M. Bradley Hanson, Martin Haulena, Kelsey Herrick, Andrew N. Hogan, Carolyn J. Hogg, Timothy A. Hore, Anna J. Jasinska, Gareth Jones, Eve Jourdain, Olga Kashpur, Harold Katcher, Etsuko Katsumata, Vimala Kaza, Hippokratis Kiaris, Michael S. Kobor, Pawel Kordowitzki, William R. Koski, Brenda Larison, Sang-Goo Lee, Marianne Lehmann, Jean-Francois Lemaitre, Andrew J. Levine, Cun Li, Xinmin Li, David TS Lin, Dana M. Lindemann, Nicholas Macoretta, Dewey Maddox, Craig O. Matkin, Julie A. Mattison, June Mergl, Jennifer J. Meudt, Gisele A. Montano, Khyobeni Mozhui, Asieh Naderi, Martina Nagy, Pritika Narayan, Peter W. Nathanielsz, Ngoc B. Nguyen, Christof Niehrs, Duncan T Odom, Alexander G. Ophir, Elaine A. Ostrander, Perrie O'Tierney Ginn, Kim M. Parsons, Kimberly C. Paul, Matteo Pellegrini, Gabriela M. Pinho, Jocelyn Plassais, Natalia A. Prado, Benjamin Rey, Beate R. Ritz, Jooke Robbins, Magdalena Rodriguez, Jennifer Russell, Elena Rydkina, Lindsay L. Sailer, Adam B. Salmon, Akshay Sanghavi, Kyle M. Schachtschneider, Dennis Schmitt, Lars Schomacher, Lawrence B. Schook, Karen E. Sears, Ashley W. Seifert, Anastasia V. Shindyapina, Kavita Singh, Ishani Sinha, Russel G. Snell, Elham Soltanmohammadi, Matthew L. Spangler, Maria Spriggs, Karen J. Steinman, Victoria J. Sugrue, Balazs Szladovits, Masaki Takasugi, Emma C. Teeling, Bill Van Bonn, Sonja C. Vernes, Harry V. Vinters, Mary C. Wallingford, Nan Wang, Gerald S. Wilkinson, Robert W. Williams, X. William Yang, Brent G. Young, Bohan Zhang, Zhihui Zhang, Peng Zhao, Yang Zhao, Wanding Zhou, Joseph A. Zoller, Jason Ernst, Andrei Seluanov, Ken Raj, Vera Gorbunova, Steve Horvath

Maximum lifespan of a species is the oldest that individuals can survive, reflecting the genetic limit of longevity in an ideal environment. Here we report methylation-based models that accurately predict maximum lifespan (r=0.89), gestational time (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fee697f5dd92102b3316fdd9b4d13a89
https://doi.org/10.1101/2021.05.16.444078

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

Autor: Roger W. Wiseman, Alexander Kamb, Steven Bayer, Robert Bogden, Keith D Harshman, Zahra Gholami, P. Andrew Futreal, Russell Bell, Charles E. Hussey, Astrid Haugen-Strano, Paul Morrison, Qingyun Liu, Cheryl Frye, Judith Rosenthal, Thanh Tran, David E. Goldgar, Tom Hattier, Frank H. Norris, Pam K. Bristow, Wei Ding, Susan L. Neuhausen, Jeff Swensen, Steven A. Narod, J. Carl Barrett, L. Michelle Bennett, Mei Lai, Harold Katcher, Daniel Shaffer, Leah M. Helvering, Patricia N. Tonin, Priya Dayananth, Lisa A. Cannon-Albright, John R. Ward, Charles Cochran, Robert Phelps, Donna M Shattuck-Eidens, Christian Wray, Steven Stone, Melody McClure, Yoshio Miki, Mark H. Skolnick, Paul Robert Rosteck, Kazuko Yakumo, Sean V. Tavtigian, Cathryn M. Lewis

Publikováno v: Scopus-Elsevier

A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast and ovarian cancer, has been identified by positional cloning methods. Probable predisposing mutations have been detected in five of eight kindreds presumed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee5e183b86bcbd5912f4949f99cad5a
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028113345&partnerID=MN8TOARS