Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Harold G. de Bruin"'
Autor:
Ilse M. Boudewijn, Alen Faiz, Katrina Steiling, Erica van der Wiel, Eef D. Telenga, Susan J. M. Hoonhorst, Nick H. T. ten Hacken, Corry-Anke Brandsma, Huib A. M. Kerstjens, Wim Timens, Irene H. Heijink, Marnix R. Jonker, Harold G. de Bruin, J. Sebastiaan Vroegop, Henk R. Pasma, Wim G. Boersma, Pascal Wielders, Frank van den Elshout, Khaled Mansour, Avrum Spira, Marc E. Lenburg, Victor Guryev, Dirkje S. Postma, Maarten van den Berge
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Nasal gene expression profiling is a promising method to characterize COPD non-invasively. We aimed to identify a nasal gene expression profile to distinguish COPD patients from healthy controls. We investigated whether this COPD-
Externí odkaz:
https://doaj.org/article/65ad28ccc1de4dada65462a59303ada5
Autor:
Dennis M. L. W. Kruk, Marissa Wisman, Jacobien A. Noordhoek, Mehmet Nizamoglu, Marnix R. Jonker, Harold G. de Bruin, Karla Arevalo Gomez, Nick H. T. ten Hacken, Simon D. Pouwels, Irene H. Heijink
Publikováno v:
Cells, Vol 10, Iss 11, p 2860 (2021)
COPD is characterized by irreversible lung tissue damage. We hypothesized that lung-derived mesenchymal stromal cells (LMSCs) reduce alveolar epithelial damage via paracrine processes, and may thus be suitable for cell-based strategies in COPD. We ai
Externí odkaz:
https://doaj.org/article/c260538f10634f8fb47eb09a8a7cee22
Autor:
Dennis Kruk, Harold G. de Bruin, Nick H. T. ten Hacken, Irene H. Heijink, Marissa Wisman, Toin H. van Kuppevelt, Janette K. Burgess, Wim Timens, Monique E. Lodewijk, Theo Borghuis, Danique J. Hof, Willeke F. Daamen
Publikováno v:
American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, 5, pp. L832-L844
American Journal of Physiology-Lung Cellular and Molecular Physiology, 320(5), L832-L844. AMER PHYSIOLOGICAL SOC
American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, L832-L844
American Journal of Physiology-Lung Cellular and Molecular Physiology, 320(5), L832-L844. AMER PHYSIOLOGICAL SOC
American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, L832-L844
Mesenchymal stromal cells (MSCs) may provide crucial support in the regeneration of destructed alveolar tissue (emphysema) in chronic obstructive pulmonary disease (COPD). We hypothesized that lung-derived MSCs (LMSCs) from patients with emphysema ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83274e106e727ec3401c6bf08967d530
https://research.rug.nl/en/publications/ab66799e-cdf9-4fd3-b58c-27e4ac91cd27
https://research.rug.nl/en/publications/ab66799e-cdf9-4fd3-b58c-27e4ac91cd27
Autor:
Darryl A. Knight, Jacobien A. Noordhoek, Marnix R. Jonker, Harold G. de Bruin, Virinchi N. S. Kuchibhotla, Irene H. Heijink, Martijn C. Nawijn
Publikováno v:
Allergy, 75(7), 1786-1789. Wiley-Blackwell
Allergy
Allergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a68522cacb8a447807df20a2afd18b
https://doi.org/10.1111/all.14216
https://doi.org/10.1111/all.14216
Autor:
Mehmet Nizamoglu, Marnix R. Jonker, Harold G. de Bruin, Simon D. Pouwels, Dennis M L W Kruk, Karla F. Arevalo Gomez, Marissa Wisman, Jacobien A. Noordhoek, Nick H. T. ten Hacken, Irene H. Heijink
Publikováno v:
Cells
Volume 10
Issue 11
Cells, 10(11):2860. MDPI AG
Cells, Vol 10, Iss 2860, p 2860 (2021)
Volume 10
Issue 11
Cells, 10(11):2860. MDPI AG
Cells, Vol 10, Iss 2860, p 2860 (2021)
COPD is characterized by irreversible lung tissue damage. We hypothesized that lung-derived mesenchymal stromal cells (LMSCs) reduce alveolar epithelial damage via paracrine processes, and may thus be suitable for cell-based strategies in COPD. We ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2b21d393440b2a43f058165f183036
Autor:
Robin Dennebos, Marnix R. Jonker, Irene H. Heijink, Harold G. de Bruin, Maarten van den Berge, Jacobien A. Noordhoek, Corry-Anke Brandsma, Dirkje S. Postma
Publikováno v:
European Respiratory Journal, 48(2), 504-515. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Wingless/integrase-1 (WNT) signalling is associated with lung inflammation and repair, but its role in chronic obstructive pulmonary disease (COPD) pathogenesis is unclear. We investigated whether cigarette smoke-induced dysregulation of WNT-5B contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a43581030315e07e93c31f3ef044ac
https://doi.org/10.1183/13993003.01541-2015
https://doi.org/10.1183/13993003.01541-2015
Autor:
Katrina Steiling, Marc E. Lenburg, J. Sebastiaan Vroegop, Ilse M. Boudewijn, Marnix R. Jonker, Pascal Wielders, Victor Guryev, Irene H. Heijink, Huib A. M. Kerstjens, Maarten van den Berge, Erica van der Wiel, Susan J. M. Hoonhorst, Eef D. Telenga, Nick H. T. ten Hacken, Corry-Anke Brandsma, Khaled Mansour, Alen Faiz, Dirkje S. Postma, Wim Timens, Wim Boersma, Harold G. de Bruin, Avrum Spira, Henk R. Pasma, Frank van den Elshout
Publikováno v:
Respiratory Research, 18:213. BioMed Central Ltd.
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Respiratory Research
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Respiratory Research
Nasal gene expression profiling is a promising method to characterize COPD non-invasively. We aimed to identify a nasal gene expression profile to distinguish COPD patients from healthy controls. We investigated whether this COPD-associated gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dbc0ee6e3bd008c968d924b9ad8984
https://hdl.handle.net/10453/128484
https://hdl.handle.net/10453/128484
Autor:
Huib A. M. Kerstjens, Marnix R. Jonker, Marc E. Lenburg, Maarten van den Berge, Corry-Anke Brandsma, Harold G. de Bruin, Avrum Spira, Pascal Wielders, Erica van der Wiel, Susan J. M. Hoonhorst, Sebastiaan J. Vroegop, Wim Boersma, Khaled Mansour, Wim Timens, Eef D. Telenga, Frank van den Elshout, Ilse M. Boudewijn, Alen Faiz, Dirkje S. Postma, Nick H. T. ten Hacken, Henk R. Pasma, Katrina Steiling, Irene H. Heijink
Publikováno v:
European Respiratory Journal, 50(Supplement 61). EUROPEAN RESPIRATORY SOC JOURNALS LTD
Introduction: Nasal gene expression profiling is a promising method to characterize COPD non-invasively. First, we aimed to identify a nasal gene expression profile that distinguishes COPD patients from healthy controls. Next, we investigated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b76b2beae5cf808a259a4780c0260e5
https://doi.org/10.1183/1393003.congress-2017.pa4470
https://doi.org/10.1183/1393003.congress-2017.pa4470
Autor:
Dennis Kruk, Wim Timens, Irene H. Heijink, Mauricio Rojas, Willeke F. Daamen, Harold G. de Bruin, Toin H. van Kuppevelt, Nick H. T. ten Hacken, Monique E. Lodewijk, Danique J. Hof
Publikováno v:
European Respiratory Journal, 50. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03a6c5169996b833bbaf2d8022912a6
https://doi.org/10.1183/1393003.congress-2017.OA4438
https://doi.org/10.1183/1393003.congress-2017.OA4438
Autor:
Herman Meurs, Martina Schmidt, Harold G. de Bruin, Anouk Oldenburger, Irene H. Heijink, Fleur Kos, Wim Timens, Wolter Rijks, Wilfred J. Poppinga, H. Maarsingh
Publikováno v:
American Journal of Physiology-Cell Physiology, 306(6), C585-C597. AMER PHYSIOLOGICAL SOC
Airway epithelium, which forms the first barrier towards environmental insults, is disturbed by cigarette smoking, a major risk factor for developing chronic obstructive pulmonary disease (COPD). A-kinase anchoring proteins (AKAP) maintain endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d85a7d24de86f18e1112cef0a51c233
https://doi.org/10.1152/ajpcell.00183.2013
https://doi.org/10.1152/ajpcell.00183.2013