Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Harold Elias"'
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with high metastatic potential. Clinical observations suggest that there is disease heterogeneity among patients with different sites of distant metasta
Externí odkaz:
https://doaj.org/article/945c2f1b82224cd8b56e30c78e9dc84a
Autor:
Tim J, Kamerzell, Brittney, Mikell, Lei, Chen, Harold, Elias, Buddhadeb, Dawn, Calum, MacRae, C Russell, Middaugh
Publikováno v:
Advances in protein chemistry and structural biology. 130
Histone modifying enzymes regulate chromatin architecture through covalent modifications and ultimately control multiple aspects of cellular function. Disruption of histone modification leads to changes in gene expression profiles and may lead to dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1df1aeb0282ead26630cda3247030f6
https://pubmed.ncbi.nlm.nih.gov/35534108
https://pubmed.ncbi.nlm.nih.gov/35534108
Autor:
Tim J. Kamerzell, Brittney Mikell, Lei Chen, Harold Elias, Buddhadeb Dawn, Calum MacRae, C. Russell Middaugh
Publikováno v:
Protein Design and Structure ISBN: 9780323992299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db995eb08e18c929151b3c86f9fb8c5
https://doi.org/10.1016/bs.apcsb.2022.02.004
https://doi.org/10.1016/bs.apcsb.2022.02.004
Autor:
Miguel-Angel Perales, Rajmohan Murali, Alan M. Hanash, Rajya Kappangantula, Harold Elias, Akimasa Hayashi, Kate A. Markey, Chi L. Nguyen, Sergio Giralt, Susan DeWolf, Christine A. Iacobuzio-Donahue, Anqi Dai, Katherine B Nichols, Priscilla Baez, Heather Landau, Paul A Giardina, Jonathan U. Peled, Roni Tamari, John B. Slingerland, Marcel R.M. van den Brink, Robert R. Jenq
Publikováno v:
Blood. 136:21-23
Introduction: Graft-versus-host-disease (GVHD) arises from the inflammatory cascade triggered by alloreactive T cell following allogeneic hematopoietic cell transplantation (allo-HCT). The tissues most frequently involved by GVHD include the small an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f63d5bcbb4b801d03cfde9f3d0a23b
https://doi.org/10.1182/blood-2020-141018
https://doi.org/10.1182/blood-2020-141018
Autor:
Kith Pradhan, Anjali Sharma, Yanhua Wang, Ashwin Sridharan, Santiago Thibaud, Amer Assal, Amit Verma, Barry S. Zingman, Aditi Shastri, Ulrich Steidl, Rahul Polineni, Ira Braunschweig, Britta Will, Mark Chaitowitz, Justin D. Kaner, Murali Janakiram, Sakshi Jasra, Louis M. Weiss, Ioannis Mantzaris, Harold Elias
Publikováno v:
Leukemia & Lymphoma. 60:3529-3535
Even though HIV is associated with worse prognosis in many malignancies, the clinical course of myelodysplastic syndrome (MDS) in HIV + patients has not been well studied. Determining the clinical presentation and outcomes of MDS in these patients wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c939802310fe0eb6e623f4f7eb1c5089
https://doi.org/10.1080/10428194.2019.1633631
https://doi.org/10.1080/10428194.2019.1633631
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Older patients with hematologic malignancies are increasingly considered for allogeneic hematopoietic cell transplantation with encouraging outcomes. While aging-related thymic dysfunction remains a major obstacle to optimal and timely immune reconst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6789b3e471c468c3ce0c3614dec30e
Publikováno v:
Haematologica
Treatment of acute leukemia with intensive chemotherapy leads to an increased risk of myelosuppression. Luteinizing hormone (LH) blockade improves hematopoietic recovery in mice after radiation or chemotherapy, through protection of the hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a215841647a42b2b2bef85217eeb73
https://doi.org/10.3324/haematol.2020.274969
https://doi.org/10.3324/haematol.2020.274969
Autor:
William S. Eng, Christina C. Spevak, Caryn J. Ha, Gaëlle H. Martin, Harold Elias, Vinagolu K. Rajasekhar, Carolien M. Woolthuis, Christopher Y. Park, Lavanya Kannan, Amanda Ernlund, Guangjie Zhao, Shanmugapriya Selvaraj, Robert J. Schneider, Mohamed A.E. Ali
Publikováno v:
Cell Stem Cell
Cell stem cell, 26(5), 755-765.e7. CELL PRESS
Cell stem cell, 26(5), 755-765.e7. CELL PRESS
Hematopoietic stem cells (HSCs) require highly regulated rates of protein synthesis, but it is unclear if they or lineage-committed progenitors preferentially recruit transcripts to translating ribosomes. We utilized polysome profiling, RNA sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e920664658a771fd7e99fc26e3dcdaae
https://europepmc.org/articles/PMC9435590/
https://europepmc.org/articles/PMC9435590/
Publikováno v:
Translational Cancer Research. 5:S328-S331
Malignant blasts in acute myeloid leukemia (AML) are organized in a hierarchal manner resembling normal hematopoiesis, with leukemic stem cells (LSCs) at the apex, giving rise to more differentiated progeny with reduced capacity to self-renew (1). Fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391c151759afdde787de8ac131beafd3
https://doi.org/10.21037/tcr.2016.07.15
https://doi.org/10.21037/tcr.2016.07.15
Autor:
Christopher Y. Park, Amanda Ernlund, Gaëlle H. Martin, Lavanya Kannan, Robert J. Schneider, Carolien M. Woolthuis, Harold Elias, Vinagolu K. Rajasekhar, William S. Eng, Christina C. Spevak, Shanmugapriya Selvaraj
Publikováno v:
Molecular Cancer Research. 18:PR06-PR06
Acute myeloid leukemia (AML) is a clonal disorder of hematopoiesis originating in hematopoietic/stem progenitor cells characterized by impaired differentiation and the accumulation of immature blasts in the bone marrow. While genetic, transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3003f9c5d74af5a9901ad7f55d1d0e
https://doi.org/10.1158/1557-3125.pi3k-mtor18-pr06
https://doi.org/10.1158/1557-3125.pi3k-mtor18-pr06