Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Harold D. Kim"'
Autor:
Andras Karsai, Grace J. Cassidy, Aradhya P. Rajanala, Lixinhao Yang, Deniz Kerimoglu, James C. Gumbart, Harold D. Kim, Daniel I. Goldman
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Recent studies in polymer physics have created macro-scale analogs to solute microscopic polymer chains like DNA by inducing diffusive motion on a chain of beads. These bead chains have persistence lengths of O(10) links and undergo diffusive motion
Externí odkaz:
https://doaj.org/article/2bddc66b2bd449bf9ca7f9f2ef65b88d
Publikováno v:
Frontiers in Sensors, Vol 3 (2022)
Extensive research is focused on the development of highly sensitive, rapid on-site diagnostic devices. The lateral flow strip (LFS) is a paper-based point-of-care diagnostic device, which is highly promising because of its ease of use and low cost.
Externí odkaz:
https://doaj.org/article/39c5c3ff1ca7458f915d4dd06aa5c279
Autor:
P. Daniela Garcia, Robert W. Leach, Gable M. Wadsworth, Krishna Choudhary, Hua Li, Sharon Aviran, Harold D. Kim, Virginia A. Zakian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Pop1 and 6 are subunits of RNase P and RNase MRP, which process ribosomal and tRNAs. The authors show that when Pop1 and 6 are impaired, the telomerase subunit Est1 binds telomerase RNA at normal levels, but the binding is unstable. As a result, nucl
Externí odkaz:
https://doaj.org/article/60a84cb1852b4201965cf90b77707313
Publikováno v:
Biophys J
DNA strand displacement, where a single-stranded nucleic acid invades a DNA duplex, is pervasive in genomic processes and DNA engineering applications. The kinetics of strand displacement have been studied in bulk; however, the kinetics of the underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827b1c8f8ea7c251fbadc3c78f9454ac
https://doi.org/10.1016/j.bpj.2021.01.043
https://doi.org/10.1016/j.bpj.2021.01.043
Publikováno v:
J Phys Chem B
Annealing between sticky ends of DNA is an intermediate step in ligation. It can also be utilized to program specific binding sites for DNA tile and origami assembly. This reaction is generally understood as a bimolecular reaction dictated by the loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783655a2200885d529ce68c77f7cadd5
https://doi.org/10.1021/acs.jpcb.1c00432
https://doi.org/10.1021/acs.jpcb.1c00432
The hybridization and dehybridization of DNA subject to tension is relevant to fundamental genetic processes and to the design of DNA-based mechanobiology assays. While strong tension accelerates DNA melting and decelerates DNA annealing, the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459224f3efc20af2437f87a989e61860
http://arxiv.org/abs/2204.08699
http://arxiv.org/abs/2204.08699
Autor:
Harold D. Kim, Jiyoun Jeong
Publikováno v:
Nucleic Acids Research
Cyclization of DNA with sticky ends is commonly used to measure DNA bendability as a function of length and sequence, but how its kinetics depend on the rotational positioning of the sticky ends around the helical axis is less clear. Here, we measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3effd190bff923b3ed40ef144cdf5ff5
https://doi.org/10.1093/nar/gkaa207
https://doi.org/10.1093/nar/gkaa207
Autor:
Gable M, Wadsworth, Harold D, Kim
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2349
Sensitive quantification of RNA transcripts via fluorescence in situ hybridization (FISH) is a ubiquitous part of understanding quantitative gene expression in single cells. Many techniques exist to identify and localize transcripts inside the cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::032a48720a4e05ee7a9a51834b19126d
https://pubmed.ncbi.nlm.nih.gov/34718992
https://pubmed.ncbi.nlm.nih.gov/34718992
Autor:
Harold D. Kim, Gable M. Wadsworth
Publikováno v:
Microbial Systems Biology ISBN: 9781071615843
Sensitive quantification of RNA transcripts via fluorescence in situ hybridization (FISH) is a ubiquitous part of understanding quantitative gene expression in single cells. Many techniques exist to identify and localize transcripts inside the cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7874767985d4b49773ee9602cf125d84
https://doi.org/10.1007/978-1-0716-1585-0_5
https://doi.org/10.1007/978-1-0716-1585-0_5
Cu/Zn superoxide dismutase (Sod1) is a highly conserved and abundant antioxidant enzyme that detoxifies superoxide (O2⸱-) by catalyzing its conversion to dioxygen (O2) and hydrogen peroxide (H2O2). Using Saccharomyces cerevisiae and mammalian cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d1b1196d1407292df3082be311a8008
https://doi.org/10.1101/2021.03.04.433951
https://doi.org/10.1101/2021.03.04.433951