Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Harold C. Strauss"'
Autor:
Mouhamed S. Awayda, Vladimir E. Bondarenko, Harold C. Strauss, Chang Xie, Shaomeng Wang, Michael J. Morales, Yu-Jie Qu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H2364-H2377
Ca+-calmodulin (Ca2+-CaM)-dependent protein kinase II (Ca2+/CaMKII) is an important regulator of cardiac ion channels, and its inhibition may be an approach for treatment of ventricular arrhythmias. Using the two-electrode voltage-clamp technique, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55190f48a52876ea4a580185b3462b6
https://doi.org/10.1152/ajpheart.00409.2005
https://doi.org/10.1152/ajpheart.00409.2005
Publikováno v:
Biochemical and Biophysical Research Communications. 340:1167-1177
Rapidly activating Kv4 voltage-gated ion channels are found in heart, brain, and diverse other tissues including colon and uterus. Kv4.3 can co-assemble with KChIP ancillary subunits, which modify kinetic behavior. We examined the affinity and use de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab63d668cc1da5590cd0045e61a7a9b
https://doi.org/10.1016/j.bbrc.2005.12.135
https://doi.org/10.1016/j.bbrc.2005.12.135
Autor:
Harold C. Strauss, Glenna C.L. Bett, Shimin Wang, Yu-Jie Qu, Randall L. Rasmusson, Vladimir E. Bondarenko, Michael J. Morales
Publikováno v:
Biophysical Journal. 89(5):3026-3041
Kv4.3 inactivation is a complex multiexponential process, which can occur from both closed and open states. The fast component of inactivation is modulated by the N-terminus, but the mechanisms mediating the other components of inactivation are contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f4cf454b7d2f99b6bfe1e7b83cbf69
Autor:
Vladimir E. Bondarenko, Harold C. Strauss, Michael J. Morales, Yu-Jie Qu, Shimin Wang, Randall L. Rasmusson
Publikováno v:
The Journal of Physiology. 557:705-717
Rapidly inactivating, voltage-dependent K+ currents play important roles in both neurones and cardiac myocytes. Kv4 channels form the basis of these currents in many neurones and cardiac myocytes and their mechanism of inactivation appears to differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::464b5b7954c7a9c41d4f6fecdcf074af
https://doi.org/10.1113/jphysiol.2003.058578
https://doi.org/10.1113/jphysiol.2003.058578
Publikováno v:
The Journal of Physiology. 545:5-11
Kv channel interacting proteins (KChIPs) are Ca2+-binding proteins with four EF-hands. KChIPs modulate Kv4 channel gating by slowing inactivation kinetics and accelerating recovery kinetics. Thus, KChIPs are believed to be important regulators of Kv4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2192c576ba06cb9ba4867ab73bf56d0c
https://doi.org/10.1113/jphysiol.2002.031856
https://doi.org/10.1113/jphysiol.2002.031856
Publikováno v:
The Journal of Physiology. 539:649-656
Kv4 channels are believed to underlie the rapidly recovering cardiac transient outward current (I(to)) phenotype. However, heterologously expressed Kv4 channels fail to fully reconstitute the native current. Kv channel interacting proteins (KChIPs) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b064e0221a0b556e695943dd6e92d7
https://doi.org/10.1113/jphysiol.2001.015156
https://doi.org/10.1113/jphysiol.2001.015156
Publikováno v:
Aviation, space, and environmental medicine. 85(6)
INTRODUCTION Exposure to high altitude decreases arterial oxygen saturation (Sa(O2)). Previous studies have shown decreased voltage of the T wave of the electrocardiogram (ECG) at altitudes up to 7000 m (22,966 ft) secondary to hypoxia. This pilot st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b03f860360681463e5c100b0c17863
https://pubmed.ncbi.nlm.nih.gov/24919387
https://pubmed.ncbi.nlm.nih.gov/24919387
Autor:
Stephen F. Vatner, Leslie A. Leinwand, Peter Libby, Yoshio Yazaki, Eduardo Marbán, Bradford C. Berk, Thomas H. Hintze, Harold C. Strauss, Ketty Schwartz
Publikováno v:
Circulation Research. 84:1361-1364
The editorship of Circulation Research changes as of this issue. We wish Dr. Marban and his new Associate Editors well and take this opportunity to highlight some of the key features of our editorship, which began in 1991 at Boston and ends in 1999 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcc184462205b16376b2890402a6087
https://doi.org/10.1161/01.res.84.12.1361
https://doi.org/10.1161/01.res.84.12.1361
Autor:
Shuguang Liu, Randall L. Rasmusson, Donald L. Campbell, Mulugu V. Brahmajothi, Shaomeng Wang, Michael J. Morales, Harold C. Strauss
Publikováno v:
Circulation Research. 82:739-750
Abstract —Inactivation is the process by which an open channel enters a stable nonconducting conformation after a depolarizing change in membrane potential. Inactivation is a widespread property of many different types of voltage-gated ion channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac675b97312a415858eec2727ff5e9d2
https://doi.org/10.1161/01.res.82.7.739
https://doi.org/10.1161/01.res.82.7.739
Publikováno v:
FEBS Letters. 417:43-47
Rectification of HERG is due to a rapid inactivation process that has been labeled C-type inactivation and is believed to be due to closure of the external mouth of the pore. We examined the effects of mutation of extracellular residues that remove C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83720357e049fbcdb2caf8eeb7377cf3
https://doi.org/10.1016/s0014-5793(97)01245-3
https://doi.org/10.1016/s0014-5793(97)01245-3