Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Harold A. Burgess"'
Autor:
Josiah D. Zoodsma, Emma J. Keegan, Gabrielle R. Moody, Ashwin A. Bhandiwad, Amalia J. Napoli, Harold A. Burgess, Lonnie P. Wollmuth, Howard I. Sirotkin
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Background Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has complex and varied etiologies. Advances in genome sequencing have identified multiple candidate genes associated with ASD, including dozens of missense an
Externí odkaz:
https://doaj.org/article/9259b7d1d3a848e6991b30c900ffaa4d
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Many animals show individual left/right biases in motor behaviour, but underlying neural substrates have proven elusive. Here the authors describe neurons that maintain individual, context-dependent lateralisation of swimming behaviour in zebrafish.
Externí odkaz:
https://doaj.org/article/d44cf84bac4941149ebc28ff0d99d450
Autor:
Harold A. Burgess
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-2 (2018)
Abstract Harold Burgess is a Senior Investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. Work in his lab combines genetic and imaging techniques to stu
Externí odkaz:
https://doaj.org/article/c16b1c1559e14b3c8d2eb98740962788
Autor:
Kandice Fero, Sadie A. Bergeron, Eric J. Horstick, Hiba Codore, Grace H. Li, Fumihito Ono, James J. Dowling, Harold A. Burgess
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 289-298 (2014)
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction. Much remains unknown about the molecular mechanisms governing the formation of the contractile apparatus. We identified an ea
Externí odkaz:
https://doaj.org/article/de57068495434c17be84ca6ffd927455
Autor:
Kathryn M Tabor, Gregory D Marquart, Christopher Hurt, Trevor S Smith, Alexandra K Geoca, Ashwin A Bhandiwad, Abhignya Subedi, Jennifer L Sinclair, Hannah M Rose, Nicholas F Polys, Harold A Burgess
Publikováno v:
eLife, Vol 8 (2019)
Decoding the functional connectivity of the nervous system is facilitated by transgenic methods that express a genetically encoded reporter or effector in specific neurons; however, most transgenic lines show broad spatiotemporal and cell-type expres
Externí odkaz:
https://doaj.org/article/74c9f141b3f740a6879be9d3a9f04ed7
Autor:
Harold A Burgess, Edward A Burton
Publikováno v:
Oxford Open Neuroscience. 2
The last decade has seen a dramatic rise in the number of genes linked to neurological disorders, necessitating new models to explore underlying mechanisms and to test potential therapies. Over a similar period, many laboratories adopted zebrafish as
Autor:
Edward A Burton, Harold A Burgess
Publikováno v:
Oxford Open Neuroscience. 2
Extensive phylogenetic conservation of molecular pathways and neuroanatomical structures, associated with efficient methods for genetic modification, have been exploited increasingly to generate zebrafish models of human disease. A range of powerful
Autor:
Ashwin A. Bhandiwad, Nickolas C. Chu, Svetlana A. Semenova, George A. Holmes, Harold A. Burgess
Publikováno v:
Science Advances. 8
Sudden changes in the environment are frequently perceived as threats and provoke defensive behavioral states. One such state is tonic immobility, a conserved defensive strategy characterized by powerful suppression of movement and motor reflexes. To
Autor:
Alison Heffer, Gregory D Marquart, Allisan Aquilina-Beck, Nabil Saleem, Harold A Burgess, Igor B Dawid
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189162 (2017)
Potassium channel tetramerization domain containing 15 (Kctd15) was previously found to have a role in early neural crest (NC) patterning, specifically delimiting the region where NC markers are expressed via repression of transcription factor AP-2a
Externí odkaz:
https://doaj.org/article/0e9445df25b5447886623ff35cbdbd42
Autor:
Gregory D Marquart, Kathryn M Tabor, Mary eBrown, Jennifer L Strykowski, Gaurav K Varshney, Matthew C LaFave, Thomas eMueller, Shawn M Burgess, Shin-ichi eHigashijima, Harold A Burgess
Publikováno v:
Frontiers in Neural Circuits, Vol 9 (2015)
Transgenic methods enable the selective manipulation of neurons for functional mapping of neuronal circuits. Using confocal microscopy, we have imaged the cellular-level expression of 109 transgenic lines in live 6 day post fertilization larvae, incl
Externí odkaz:
https://doaj.org/article/e29e71278a8a450982d6bdc8d63b16f1