A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits.

Autor: Wietek J; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel. jonas.wietek@gmail.com.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel. jonas.wietek@gmail.com.; Neuroscience Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany. jonas.wietek@gmail.com., Nozownik A; Center for Molecular Neurobiology, Hamburg, Germany.; Paris Brain Institute, Institut du Cerveau (ICM), CNRS UMR 7225, INSERM U1127, Sorbonne Université, Paris, France., Pulin M; Center for Molecular Neurobiology, Hamburg, Germany.; Laboratory of Sensory Processing, Brain Mind Institute, Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Saraf-Sinik I; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Matosevich N; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel., Gowrishankar R; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Excellence in the Neurobiology of Addiction, Pain and Emotion, University of Washington, Seattle, WA, USA., Gat A; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Malan D; Institut für Physiologie I, University of Bonn, Bonn, Germany., Brown BJ; Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA., Dine J; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel.; Boehringer Ingelheim Pharma GmbH & Co. KG; CNS Diseases, Biberach an der Riss, Germany., Imambocus BN; LIMES-Institute, University of Bonn, Bonn, Germany., Levy R; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Sauter K; Center for Molecular Neurobiology, Hamburg, Germany., Litvin A; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Regev N; Department of Physiology and Pharmacology, Tel Aviv University, Tel Aviv, Israel., Subramaniam S; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Abrera K; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA., Summarli D; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA., Goren EM; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; University of Michigan, Ann Arbor, MI, USA., Mizrachi G; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Bitton E; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Benjamin A; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Copits BA; Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA., Sasse P; Institut für Physiologie I, University of Bonn, Bonn, Germany., Rost BR; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuroscience Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany., Schmitz D; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuroscience Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Bernstein Center for Computational Neuroscience, Berlin, Germany.; Einstein Center for Neurosciences, Berlin, Germany.; Max Delbrück Center for Molecular Medicine, Berlin, Germany., Bruchas MR; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Excellence in the Neurobiology of Addiction, Pain and Emotion, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA., Soba P; LIMES-Institute, University of Bonn, Bonn, Germany.; Institute of Physiology and Pathophysiology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Oren-Suissa M; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel., Nir Y; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; Department of Physiology and Pharmacology, Tel Aviv University, Tel Aviv, Israel.; Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel., Wiegert JS; Center for Molecular Neurobiology, Hamburg, Germany.; MCTN, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany., Yizhar O; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel. ofer.yizhar@weizmann.ac.il.; Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel. ofer.yizhar@weizmann.ac.il.

Publikováno v: Nature methods [Nat Methods] 2024 Jul; Vol. 21 (7), pp. 1275-1287. Date of Electronic Publication: 2024 May 29.

Age-dependent dystonia in striatal Gγ7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole.

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International Review of Neurobiology

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial p