Digital twin mathematical models suggest individualized hemorrhagic shock resuscitation strategies.

Autor: Cannon JW; Division of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. jeremy.cannon@pennmedicine.upenn.edu.; Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. jeremy.cannon@pennmedicine.upenn.edu., Gruen DS; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Trauma Research Center, Pittsburgh, PA, 15213, USA., Zamora R; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Trauma Research Center, Pittsburgh, PA, 15213, USA.; Center for Inflammation and Regeneration Modeling, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 15219, USA., Brostoff N; Immunetrics, now wholly owned by Simulations Plus, Pittsburgh, PA, 15219, USA., Hurst K; Immunetrics, now wholly owned by Simulations Plus, Pittsburgh, PA, 15219, USA., Harn JH; Immunetrics, now wholly owned by Simulations Plus, Pittsburgh, PA, 15219, USA., El-Dehaibi F; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Geng Z; Division of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA., Namas R; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Trauma Research Center, Pittsburgh, PA, 15213, USA., Sperry JL; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Trauma Research Center, Pittsburgh, PA, 15213, USA., Holcomb JB; Department of Surgery, University of Alabama, Birmingham, AL, 35233, USA., Cotton BA; Division of Acute Care Surgery, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Nam JJ; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Underwood S; Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, Portland, OR, 97239, USA., Schreiber MA; Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, Portland, OR, 97239, USA., Chung KK; SeaStar Medical, Denver, CO, 80216, USA., Batchinsky AI; Autonomous Reanimation and Evacuation (AREVA) Research and Innovation Center, San Antonio, TX, 78235, USA., Cancio LC; US Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA., Benjamin AJ; Trauma and Acute Care Surgery, Department of Surgery, The University of Chicago, Chicago, IL, 60637, USA., Fox EE; Division of Acute Care Surgery, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Chang SC; Immunetrics, now wholly owned by Simulations Plus, Pittsburgh, PA, 15219, USA., Cap AP; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA., Vodovotz Y; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Pittsburgh Trauma Research Center, Pittsburgh, PA, 15213, USA.; Center for Inflammation and Regeneration Modeling, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 15219, USA.; Center for Systems Immunology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

Publikováno v: Communications medicine [Commun Med (Lond)] 2024 Jun 12; Vol. 4 (1), pp. 113. Date of Electronic Publication: 2024 Jun 12.