Zobrazeno 1 - 10
of 560
pro vyhledávání: '"Harminder S. Dua"'
Autor:
Zun Zheng Ong, Youssef Sadek, Riaz Qureshi, Su-Hsun Liu, Tianjing Li, Xiaoxuan Liu, Yemisi Takwoingi, Viknesh Sounderajah, Hutan Ashrafian, Daniel S.W. Ting, Jodhbir S. Mehta, Saaeha Rauz, Dalia G. Said, Harminder S. Dua, Matthew J. Burton, Darren S.J. Ting
Publikováno v:
EClinicalMedicine, Vol 77, Iss , Pp 102887- (2024)
Summary: Background: Infectious keratitis (IK) is the leading cause of corneal blindness globally. Deep learning (DL) is an emerging tool for medical diagnosis, though its value in IK is unclear. We aimed to assess the diagnostic accuracy of DL for I
Externí odkaz:
https://doaj.org/article/6a8fc0f9f1624ff18e9e9088b6d9ce69
Autor:
Yasmeen Hammoudeh, Lakshmi Suresh, Zun Zheng Ong, Michelle M. Lister, Imran Mohammed, D. John I. Thomas, Jennifer L. Cottell, Jennifer M. Holden, Dalia G. Said, Harminder S. Dua, Darren Shu Jeng Ting
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundTo compare the diagnostic performance of microbiological culture and 16S/18S rRNA gene polymerase chain reaction (PCR)-Sanger sequencing for infectious keratitis (IK) and to analyse the effect of clinical disease severity on test performanc
Externí odkaz:
https://doaj.org/article/f9e52f0305a7414292ad9ef37bda900f
Autor:
Christiane Kafarnik, Lana A. Faraj, Darren S. J. Ting, Jia Ni Goh, Dalia G. Said, Harminder S. Dua
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The recent discovery and characterization of pre-Descemet’s layer (PDL; also termed the Dua’s layer or the Dua-Fine layer) has advanced the understanding of various posterior corneal pathologies and surgeries in human. This study aimed t
Externí odkaz:
https://doaj.org/article/b71ec09c89f04228a22d8534ab7470f0
Autor:
Zun Zheng Ong, Thai Ling Wong, Lakshmi Suresh, Yasmeen Hammoudeh, Michelle Lister, Dalia G. Said, Harminder S. Dua, Darren S. J. Ting
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Background/objectivesPost-keratoplasty infectious keratitis (PKIK) is a unique sight-threatening clinical entity which often poses significant therapeutic challenges. This study aimed to examine the clinical presentation, risk factors, management, an
Externí odkaz:
https://doaj.org/article/5fd31512daa345e6abe12b63b011eadc
Autor:
Rashmi Deshmukh, Zun Zheng Ong, Radhika Rampat, Jorge L. Alió del Barrio, Ankur Barua, Marcus Ang, Jodhbir S. Mehta, Dalia G. Said, Harminder S. Dua, Renato Ambrósio, Darren Shu Jeng Ting
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Keratoconus is the most common corneal ectatic disorder. It is characterized by progressive corneal thinning with resultant irregular astigmatism and myopia. Its prevalence has been estimated at 1:375 to 1:2,000 people globally, with a considerably h
Externí odkaz:
https://doaj.org/article/c397978efb7145cfbf67ab761de9e973
Autor:
Darren Shu Jeng Ting, Eunice Tze Leng Goh, Venkatesh Mayandi, Joanna M. F. Busoy, Thet Tun Aung, Mercy Halleluyah Periayah, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Hla M. Htoon, Veluchamy Amutha Barathi, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationall
Externí odkaz:
https://doaj.org/article/b8964e8c144045dd99c424d45d86d9a4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Infectious keratitis (IK) is the 5th leading cause of blindness globally. Broad-spectrum topical antimicrobial treatment is the current mainstay of treatment for IK, though adjuvant treatment or surgeries are often required in refractory cas
Externí odkaz:
https://doaj.org/article/c164ba482cbd4f2a926fa82b7141aff6
Autor:
Leonardo Mastropasqua, Mario Nubile, Giuseppina Acerra, Nicola Detta, Letizia Pelusi, Manuela Lanzini, Simone Mattioli, Manuela Santalucia, Laura Pietrangelo, Marcello Allegretti, Harminder S. Dua, Jodhbir S. Mehta, Assunta Pandolfi, Domitilla Mandatori
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Small incision lenticule extraction (SMILE), is a surgical procedure for the myopia correction, during which a corneal stromal lenticule is extracted. Given that we have previously demonstrated how this discarded tissue could be repurposed as a bio-s
Externí odkaz:
https://doaj.org/article/ecaf2b8093d14cd38b7aaf66018ceaa1
Autor:
Darren Shu Jeng Ting, Imran Mohammed, Rajamani Lakshminarayanan, Roger W. Beuerman, Harminder S. Dua
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sight is arguably the most important sense in human. Being constantly exposed to the environmental stress, irritants and pathogens, the ocular surface – a specialized functional and anatomical unit composed of tear film, conjunctival and corneal ep
Externí odkaz:
https://doaj.org/article/884c876046c4495898cbbdd11b0f356a
Autor:
Darren Shu Jeng Ting, Jianguo Li, Chandra S. Verma, Eunice T. L. Goh, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background/Aim: Host defense peptides (HDPs) have the potential to provide a novel solution to antimicrobial resistance (AMR) in view of their unique and broad-spectrum antimicrobial activities. We had recently developed a novel hybrid HDP based on L
Externí odkaz:
https://doaj.org/article/65f70df69b1e420d94e11d23b971b8e6