Data from Changes in the Glycosylation of Kininogen and the Development of a Kininogen-Based Algorithm for the Early Detection of HCC

Autor: Anand Mehta, Radoslav Goldman, Timothy Block, Jorge Marrero, Amit G. Singal, Yuko Kono, Charles Swindell, Harmin Herrera, Mary Ann Comunale, Miloslav Sanda, Mengjun Wang

Background: Hepatocellular carcinoma (HCC) has the greatest increase in mortality among all solids tumors in the United States related to low rates of early tumor detection. Development of noninvasive biomarkers for the early detection of HCC may red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e5a3fccd8690b83835f5dd2650e297
https://doi.org/10.1158/1055-9965.c.6515368

Biomarker analysis of fucosylated kininogen through depletion of lectin reactive heterophilic antibodies in hepatocellular carcinoma

Autor: Lu Renquan, Mengjun Wang, Jiabin Shen, Amit G. Singal, Anand Mehta, Charles Swindell, Harmin Herrera

Publikováno v: Journal of Immunological Methods. 462:59-64

Hepatocellular carcinoma (HCC) accounts for >700,000 deaths worldwide, largely related to poor rates of diagnosis. Our previous work identified glycoproteins with increased levels of fucosylation in HCC. Plate-based assays to measure this change were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b209ad77ac92786ab8f1c6154890e57
https://doi.org/10.1016/j.jim.2018.08.010

Core-Fucosylated Tetra-Antennary N-Glycan Containing A Single N-Acetyllactosamine Branch Is Associated with Poor Survival Outcome in Breast Cancer

Autor: Peggi M. Angel, Harmin Herrera, Mengjun Wang, Joelle N. Zambrano, Tinslee Dilday, Allison Uber, Elizabeth S. Yeh, Elizabeth G. Hill, Danielle A Scott, Anand Mehta, Richard R. Drake

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 10
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2528 (2019)

(1) Glycoproteins account for ~80% of proteins located at the cell surface and in the extracellular matrix. A growing body of evidence indicates that &alpha
L-fucose protein modifications contribute to breast cancer progression and metastatic di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43b5a22cfbd841dfd3e25d1b8883c5c

Effect of Row Spacing on Seed Isoflavone Contents in Soybean [Glycine max (L.) Merr.]

Autor: My Abdelmajid Kassem, Stella K. Kantartzi, Masum Akond, Bobby Ragin, Khalid Meksem, Harmin Herrera, David A. Lightfoot, Cevdet Akbay

Publikováno v: American Journal of Plant Sciences. :4003-4010

Soybean isoflavones compounds such as genistein, daidzein, and glycitein have numerous human health benefits including the reduction of risks of cardiovascular diseases, breast and prostate cancers, and menaupose symptoms in women. Understanding the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd21ded4d7b60f8d6ed94551b1107bbd
https://doi.org/10.4236/ajps.2014.526418

Development and application of a novel recombinant Aleuria aurantia lectin with enhanced core fucose binding for identification of glycoprotein biomarker of hepatocellular carcinoma

Autor: Mengjun Wang, Anand Mehta, Josef Houser, Harmin Herrera, Michaela Wimmerová, Mary Ann Comunale, Patrick R. Romano, Pamela A. Norton

The Aleuria aurantia lectin (AAL) derived from orange peel fungus contains five fucose-binding sites that recognizes fucose bound in α-1,2, α-1,3, α-1,4, and α-1,6 linkages to N-acetylglucosamine and galactose. Recently, we have created several r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e61158201396fb928c4af6fb2b70785
https://europepmc.org/articles/PMC5869706/