Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Harm-Jan Pieters"'
1
Akademický článek
The intestinal barrier in irritable bowel syndrome: subtype-specific effects of the systemic compartment in an in vitro model.
Autor: Samefko Ludidi, Daisy Jonkers, Elhaseen Elamin, Harm-Jan Pieters, Esther Schaepkens, Paul Bours, Joanna Kruimel, José Conchillo, Ad Masclee
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0123498 (2015)
Irritable bowel syndrome (IBS) is a disorder with multifactorial pathophysiology. Intestinal barrier may be altered, especially in diarrhea-predominant IBS (IBS-D). Several mediators may contribute to increased intestinal permeability in IBS.We aimed
Externí odkaz: https://doaj.org/article/12adf70cb711402694bff1ec5739ed02
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2
Akademický článek
Ethanol impairs intestinal barrier function in humans through mitogen activated protein kinase signaling: a combined in vivo and in vitro approach.
Autor: Elhaseen Elamin, Ad Masclee, Freddy Troost, Harm-Jan Pieters, Daniel Keszthelyi, Katarina Aleksa, Jan Dekker, Daisy Jonkers
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107421 (2014)
Ethanol-induced gut barrier disruption is associated with several gastrointestinal and liver disorders.Since human data on effects of moderate ethanol consumption on intestinal barrier integrity and involved mechanisms are limited, the objectives of
Externí odkaz: https://doaj.org/article/b211920415774080a3d63f8c1995f9ad
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3
Akademický článek
Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model.
Autor: Elhaseen Elamin, Ad Masclee, Kati Juuti-Uusitalo, Sven van Ijzendoorn, Freddy Troost, Harm-Jan Pieters, Jan Dekker, Daisy Jonkers
Publikováno v: PLoS ONE, Vol 8, Iss 3, p e58561 (2013)
Background & aimsEvidence is accumulating that ethanol and its oxidative metabolite, acetaldehyde, can disrupt intestinal epithelial integrity, an important factor contributing to ethanol-induced liver injury. However, ethanol can also be metabolized
Externí odkaz: https://doaj.org/article/dbfaadaf204848309a5706096b30c17e
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4
Replacement of Nitrite in Meat Products by Natural Bioactive Compounds Results in Reduced Exposure to N-Nitroso Compounds: The PHYTOME Project
Autor: Virag Sagi-Kiss, Yung Hung, Harm-Jan Pieters, Simone G. J. van Breda, Theo M. de Kok, Karen Mathijs, Gunter G. C. Kuhnle, Giovanna Saccani, Adriaan A. van Bodegraven, Roberta Virgili, Ad A.M. Masclee, Giovanni Parolari, Wim Verbeke, Panagiotis Georgiadis, Rashmi Sinha, Gert Hemke, Carla B.E.M. Vleugels-Simon
Publikováno v: Molecular Nutrition & Food Research, 65(20):2001214. Wiley
MOLECULAR NUTRITION & FOOD RESEARCH
Mol Nutr Food Res
SCOPE: It has been proposed that endogenously formed N-nitroso compounds (NOCs) are partly responsible for the link between red meat consumption and colorectal cancer (CRC) risk. As nitrite has been indicated as critical factor in the formation of NO
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f4cf4f09b9c252c212f50213d31da4
https://cris.maastrichtuniversity.nl/en/publications/ab54e9ca-5f87-42a9-ac5d-b20fb636c3e1
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6
The effects of Lactobacillus plantarum on small intestinal barrier function and mucosal gene transcription; a randomized double-blind placebo controlled trial
Autor: Zlatan Mujagic, Mark V. Boekschoten, Paul de Vos, Peter A. Bron, Freddy J. Troost, Nicole de Wit, Harm-Jan Pieters, Coen Govers, Ad A.M. Masclee
Publikováno v: Scientific Reports, 7:40128. Nature Publishing Group
Scientific Reports
Scientific Reports, 7
Scientific Reports 7 (2017)
The aim of this study was to investigate the effects of three Lactobacillus plantarum strains on in-vivo small intestinal barrier function and gut mucosal gene transcription in human subjects. The strains were selected for their differential effects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e3fb7adda2f92a3048fedd37acb729
https://doi.org/10.1038/srep40128
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7
The intestinal barrier in irritable bowel syndrome: subtype-specific effects of the systemic compartment in an in vitro model
Autor: Samefko Ludidi, Ad A.M. Masclee, Elhaseen Elamin, José M. Conchillo, Harm-Jan Pieters, Joanna W. Kruimel, Paul Bours, Esther Schaepkens, Daisy Jonkers
Publikováno v: PLoS ONE
PLOS ONE, 10(5):e0123498. Public Library of Science
PLoS ONE, Vol 10, Iss 5, p e0123498 (2015)
BACKGROUND: Irritable bowel syndrome (IBS) is a disorder with multifactorial pathophysiology. Intestinal barrier may be altered, especially in diarrhea-predominant IBS (IBS-D). Several mediators may contribute to increased intestinal permeability in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d39d5b8886d26767808228ac30ca955
https://pubmed.ncbi.nlm.nih.gov/25978614
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8
Ethanol Impairs Intestinal Barrier Function in Humans through Mitogen Activated Protein Kinase Signaling: A Combined In Vivo and In Vitro Approach
Autor: Katarina Aleksa, Ad A.M. Masclee, Daisy Jonkers, Jan Dekker, Daniel Keszthelyi, Elhaseen Elamin, Freddy J. Troost, Harm-Jan Pieters
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107421 (2014)
PLoS ONE
PLOS ONE, 9(9):e107421. Public Library of Science
PLoS ONE 9 (2014) 9
PLoS ONE, 9(9)
Background: Ethanol-induced gut barrier disruption is associated with several gastrointestinal and liver disorders. Aim: Since human data on effects of moderate ethanol consumption on intestinal barrier integrity and involved mechanisms are limited,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3f7312b68fc814087d5ede04adb2bc
https://doi.org/10.1371/journal.pone.0107421
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9
Short-Chain Fatty Acids Activate AMP-Activated Protein Kinase and Ameliorate Ethanol-Induced Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers
Autor: Ad A.M. Masclee, Harm-Jan Pieters, Elhaseen Elamin, Jan Dekker, Daisy Jonkers
Publikováno v: Journal of Nutrition, 143(12), 1872-1881. Oxford University Press
The Journal of Nutrition 143 (2013) 12
The Journal of Nutrition, 143(12), 1872-1881
Short-chain fatty acids (SCFAs) have been shown to promote intestinal barrier function, but their protective effects against ethanol-induced intestinal injury and underlying mechanisms remain essentially unknown. The aim of the study was to analyze t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcdaf31b6a8fad173f9fdb87baeea2d
https://cris.maastrichtuniversity.nl/en/publications/15a8996e-9a0f-4088-b6e8-ccf6e599b4c2
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10
Fatty Acid Ethyl Esters Induce Intestinal Epithelial Barrier Dysfunction via a Reactive Oxygen Species-Dependent Mechanism in a Three-Dimensional Cell Culture Model
Autor: Daisy Jonkers, Kati Juuti-Uusitalo, Freddy J. Troost, Elhaseen Elamin, Harm-Jan Pieters, Ad A.M. Masclee, Sven C.D. van IJzendoorn, Jan Dekker
Publikováno v: PLoS ONE 8 (2013) 3
PLoS ONE, Vol 8, Iss 3, p e58561 (2013)
PLoS ONE, 8(3):e58561. PUBLIC LIBRARY SCIENCE
PLoS ONE, 8(3)
PLOS ONE, 8(3):58561. Public Library of Science
PLoS ONE
Background & Aims Evidence is accumulating that ethanol and its oxidative metabolite, acetaldehyde, can disrupt intestinal epithelial integrity, an important factor contributing to ethanol-induced liver injury. However, ethanol can also be metabolize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c011dcd5214284595ca8464a2df4ea
https://doi.org/10.1371/journal.pone.0058561
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