Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Harm de Wit"'
Autor:
Yvonne M. Mueller, Thijs J. Schrama, Rik Ruijten, Marco W. J. Schreurs, Dwin G. B. Grashof, Harmen J. G. van de Werken, Giovanna Jona Lasinio, Daniel Álvarez-Sierra, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Manzhi Zhao, Ling Li, Harm de Wit, Christos A. Ouzounis, Merel E. P. Wilmsen, Tessa M. Alofs, Danique A. Laport, Tamara van Wees, Geoffrey Kraker, Maria C. Jaimes, Sebastiaan Van Bockstael, Manuel Hernández-González, Casper Rokx, Bart J. A. Rijnders, Ricardo Pujol-Borrell, Peter D. Katsikis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Developing predictive methods to identify patients with high risk of severe COVID-19 disease is of crucial importance. Authors show here that by measuring anti-SARS-CoV-2 antibody and cytokine levels at the time of hospital admission and integrating
Externí odkaz:
https://doaj.org/article/8868b5c6ee1046f79b63a7f738da79df
Autor:
Sylvia Kamphuis, Cornelia G van Helden-Meeuwsen, Marjan A Versnel, Anton W Langerak, Mohamed Javad Wahadat, Marleen Verkaaik, Sander J van Tilburg, Yvonne M Mueller, Harm de Wit, Marike J Gruijters, Amani Mubarak, Peter D Katsikis
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss 1 (2023)
Objective To combine targeted transcriptomic and proteomic data in an unsupervised hierarchical clustering method to stratify patients with childhood-onset SLE (cSLE) into similar biological phenotypes, and study the immunological cellular landscape
Externí odkaz:
https://doaj.org/article/2d3bcbf14b7045219b7b1e461c9d0968
Autor:
Lucy Baldeón R, Karin Weigelt, Harm de Wit, Behiye Ozcan, Adri van Oudenaren, Fernando Sempértegui, Eric Sijbrands, Laura Grosse, Anton-Jan van Zonneveld, Hemmo A Drexhage, Pieter J M Leenen
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129421 (2015)
To study the expression pattern of microRNAs and mRNAs related to inflammation in T2D monocytes.A microRNA finding study on monocytes of T2D patients and controls using array profiling was followed by a quantitative Real Time PCR (qPCR) study on mono
Externí odkaz:
https://doaj.org/article/89a7614d74084e56a4d2674898183a20
Autor:
Lucy Baldeón R, Karin Weigelt, Harm de Wit, Behiye Ozcan, Adri van Oudenaren, Fernando Sempértegui, Eric Sijbrands, Laura Grosse, Wilma Freire, Hemmo A Drexhage, Pieter J M Leenen
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115209 (2014)
There is increasing evidence that chronic inflammation is an important determinant in insulin resistance and in the pathogenesis of type 2 diabetes (T2D). MicroRNAs constitute a newly discovered system of cell regulation and in particular two microRN
Externí odkaz:
https://doaj.org/article/5dc645a9d852445dbe309992ec007cda
Autor:
Mohamed Javad Wahadat, Sander J van Tilburg, Yvonne M Mueller, Harm de Wit, Cornelia G Van Helden-Meeuwsen, Anton W Langerak, Marike J Gruijters, Amani Mubarak, Marleen Verkaaik, Peter D Katsikis, Marjan A Versnel, Sylvia Kamphuis
Publikováno v:
Lupus Science and Medicine, 10(1):e000799. BMJ Publishing Group
ObjectiveTo combine targeted transcriptomic and proteomic data in an unsupervised hierarchical clustering method to stratify patients with childhood-onset SLE (cSLE) into similar biological phenotypes, and study the immunological cellular landscape t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195d94fd5b16161739faf0d9aec3deed
https://pure.eur.nl/en/publications/d060df1a-5129-449d-a1c9-57af7705d246
https://pure.eur.nl/en/publications/d060df1a-5129-449d-a1c9-57af7705d246
Autor:
Sara Poletti, Marion Leboyer, Bartholomeus C M Haarman, Gara Arteaga-Henríquez, Maria S Simon, Annemarie J. M. Wijkhuijs, Carmen Schiweck, Olya Mikova, Richard Musil, Volker Arolt, Elske Vrieze, Stephan Claes, Francesco Benedetti, Raf Berghmans, W A Dik, Silke Joergens, Roberto Furlan, Bernhard T. Baune, Hemmo A. Drexhage, Markus J. Schwarz, Harm de Wit, Norbert Müller
Publikováno v:
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 111:110391. PERGAMON-ELSEVIER SCIENCE LTD
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 111:110391. Elsevier Inc.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 111:110391. Elsevier Inc.
BACKGROUND: The macrophage theory of depression states that macrophages play an important role in Major Depressive Disorder (MDD). METHODS: MDD patients (N = 140) and healthy controls (N = 120) participated in a cross-sectional study investigating th
Autor:
Thijs J Schrama, Danique A. Laport, Caoimhe H. Kiernan, Manzhi Zhao, Bart J. A. Rijnders, Casper Rokx, Sebastiaan Van Bockstael, Maria C. Jaimes, Ling Li, Dwin G.B. Grashof, Christos A. Ouzounis, Merel E. P. Wilmsen, Daniel Alvarez de la Sierra, Harmen J.G. van de Werken, Tamara van Wees, Inge Brouwers-Haspels, Manuel Hernández-González, Melisa D. Castro Eiro, Marco W.J. Schreurs, Marjan van Meurs, Geoffrey Kraker, Yvonne M. Mueller, Ricardo Pujol-Borrell, Peter D. Katsikis, Harm de Wit, Rik Ruijten, Tessa Alofs
Quantitative or qualitative differences in immunity may drive and predict clinical severity in COVID-19. We therefore measured modules of serum pro-inflammatory, anti-inflammatory and anti-viral cytokines in combination with the anti-SARS-CoV-2 antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee7016575b8d7f20a18e3f8667441e0
https://doi.org/10.1101/2021.05.07.21256531
https://doi.org/10.1101/2021.05.07.21256531
Autor:
Clara Locatelli, Benedetta Vai, Francesco Benedetti, Harm de Wit, Thomas A. Hoogenboezem, Cristina Colombo, Sara Poletti, Annemarie J. M. Wijkhuijs, Davide Ghiglino, Giovanni Leone, Hemmo A. Drexhage
Publikováno v:
Psychiatry Research-Neuroimaging, 285, 64-66. Elsevier Ireland Ltd
Psychiatry Research: Neuroimaging
Psychiatry Research: Neuroimaging
We tested if peripheral levels of cytokines and chemokines associate to grey matter volumes, cortical thickness and fMRI neural responses to a moral valence decision task in bipolar patients. ICAM1 and CCL4 negatively correlated with cortical thickne
Autor:
Oliver Ambrée, Clara Locatelli, Thomas A. Hoogenboezem, Hemmo A. Drexhage, Benedetta Vai, Cristina Colombo, Elena Mazza, Enrico Smeraldi, Annemarie J. M. Wijkhuijs, Sara Poletti, Harm de Wit, Francesco Benedetti, Chiara Bulgarelli, Volker Arolt
Publikováno v:
Journal of NeuroImmune Pharmacology, 11(2), 248-258. Springer New York
Growth factors involved in neurogenesis and neuroplasticity could play a role in biological processes that drive depression recovery. Combined total sleep deprivation and morning light therapy (TSDÂ +Â LT) can acutely reverse depressive symptoms, t
Autor:
Sara Poletti, Clara Locatelli, Volker Arolt, Francesco Benedetti, Irene Bollettini, Harm de Wit, Oliver Ambrée, Annemarie J. M. Wijkhuijs, Thomas A. Hoogenboezem, Hemmo A. Drexhage, Cristina Colombo, Elena Mazza
Publikováno v:
Journal of Affective Disorders, 202, 1-9. Elsevier
Background: Bipolar Disorder (BD) is associated with elevated biomarkers of cell-mediated immune activation and inflammation and with signs of widespread disruption of white matter (WM) integrity in adult life. Consistent findings in animal models li