Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Harm J. Krugers"'
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100636- (2024)
The early postnatal period is a sensitive time window that is characterized by several neurodevelopmental processes that define neuronal architecture and function later in life. Here, we examined in young adult mice, using an auditory fear conditioni
Externí odkaz:
https://doaj.org/article/96be707b5bcd4211b34eb831e39f6224
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Background Successful aging is often linked to individual’s ability to demonstrate resilience: the maintenance or quick recovery of functional ability, well-being, and quality of life despite losses or adversity. A crucial element of resil
Externí odkaz:
https://doaj.org/article/be753da3114c494d9f73c612882c85d8
Autor:
Lotte P. Brinkhof, Karoline B. S. Huth, Jaap M. J. Murre, Sanne de Wit, Harm J. Krugers, K. Richard Ridderinkhof
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/be41c7c9e35040b897a0a144d0221073
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
While aging is an important risk factor for neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease, age-related cognitive decline can also manifest without apparent neurodegenerative changes. In this review, we discuss mo
Externí odkaz:
https://doaj.org/article/79a8f8c5bfe7464baea9a86b38034dcf
Autor:
Lotte P. Brinkhof, Karoline B. S. Huth, Jaap M. J. Murre, Sanne de Wit, Harm J. Krugers, K. Richard Ridderinkhof
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Age-related challenges and transitions can have considerable social, psychological, and physical consequences that may lead to significant changes in quality of life (QoL). As such, maintaining high levels of QoL in later life may crucially depend on
Externí odkaz:
https://doaj.org/article/8e5f008a1ee144d39ceb457df66cfefd
Autor:
Sylvie L. Lesuis, Lianne Hoeijmakers, Aniko Korosi, Susanne R. de Rooij, Dick F. Swaab, Helmut W. Kessels, Paul J. Lucassen, Harm J. Krugers
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-20 (2018)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a high prevalence among the elderly and a huge personal and societal impact. Recent epidemiological studies have indicated that the incidence and age of o
Externí odkaz:
https://doaj.org/article/a2b5f03bb3de424984b5908246247281
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Stress hormones, such as corticosteroids, modulate the transmission of hippocampal glutamatergic synapses and NMDA receptor (NMDAR)-dependent synaptic plasticity, favouring salient behavioural responses to the environment. The corticosterone
Externí odkaz:
https://doaj.org/article/f1810306ce7a4bee8a385cf0fe366aa8
Autor:
Harm J. Krugers, J. Marit Arp, Hui Xiong, Sofia Kanatsou, Sylvie L. Lesuis, Aniko Korosi, Marian Joels, Paul J. Lucassen
Publikováno v:
Neurobiology of Stress, Vol 6, Iss C, Pp 14-21 (2017)
The early postnatal period is a highly sensitive time period for the developing brain, both in humans and rodents. During this time window, exposure to adverse experiences can lastingly impact cognitive and emotional development. In this review, we b
Externí odkaz:
https://doaj.org/article/27a91ddaecff4801874f401a8601886f
Autor:
Sofia Kanatsou, Henk Karst, Despoina Kortesidou, Rachelle A. van den Akker, Jan den Blaauwen, Anjanette P. Harris, Jonathan R. Seckl, Harm J. Krugers, Marian Joels
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Evidence from human studies suggests that high expression of brain mineralocorticoid receptors (MR) may promote resilience against negative consequences of stress exposure, including childhood trauma. We examined, in mice, whether brain MR overexpres
Externí odkaz:
https://doaj.org/article/1d39ba41bc8e4ef595882a0c6fdb6e2e
Autor:
Marian Joëls, Harm J. Krugers
Publikováno v:
Neural Plasticity, Vol 2007 (2007)
When an organism is exposed to a stressful situation, corticosteroid levels in the brain rise. This rise has consequences for behavioral performance, including memory formation. Over the past decades, it has become clear that a rise in corticosteroid
Externí odkaz:
https://doaj.org/article/144d27c529294f688ac3faadb30330b2