Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Harm HogenEsch"'
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract A critical aspect of cancer vaccine development is the formulation with effective adjuvants. This study evaluated whether combining a cationic plant-derived nanoparticle adjuvant (Nano-11) with the clinically tested STING agonist ADU-S100 (M
Externí odkaz:
https://doaj.org/article/cfb9c57673864443b24aa9835069823c
Autor:
Dina Bugybayeva, Ekachai Dumkliang, Veerupaxagouda Patil, Ganesh Yadagiri, Raksha Suresh, Mithilesh Singh, Jennifer Schrock, Sara Dolatyabi, Olaitan C. Shekoni, Hadi M. Yassine, Praneet Opanasopit, Harm HogenEsch, Gourapura J. Renukaradhya
Publikováno v:
Vaccines, Vol 12, Iss 6, p 647 (2024)
This study focuses on the development and characterization of an intranasal vaccine platform using adjuvanted nanoparticulate delivery of swine influenza A virus (SwIAV). The vaccine employed whole inactivated H1N2 SwIAV as an antigen and STING-agoni
Externí odkaz:
https://doaj.org/article/c0829d12f4c74568b3e8a80730164ae2
Autor:
Rebecca N. Klopp, Juan F. Hernandez Franco, Harm Hogenesch, Tana S. Dennis, Kate E. Cowles, Jacquelyn P. Boerman
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 9, Pp 7738-7749 (2022)
ABSTRACT: It is necessary for the dairy industry to reduce calf morbidity and mortality, and the reliance on antibiotics to treat sick calves, to address the growing concern regarding antibiotic resistant bacteria. The primary objective of this study
Externí odkaz:
https://doaj.org/article/198cd23d92a045e7b8c7c0901b78c790
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Candida auris, an emerging multi-drug resistant fungal pathogen, causes invasive infections in humans. The factors regulating the colonization of C. auris in host niches are not well understood. In this study, we examined the effect of antibiotic-ind
Externí odkaz:
https://doaj.org/article/521bf4d55baa49f6b9bb6c05111e475b
Autor:
Juan F. Hernandez-Franco, Ganesh Yadagiri, Veerupaxagouda Patil, Dina Bugybayeva, Sara Dolatyabi, Ekachai Dumkliang, Mithilesh Singh, Raksha Suresh, Fatema Akter, Jennifer Schrock, Gourapura J. Renukaradhya, Harm HogenEsch
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1699 (2023)
The development of cross-protective vaccines against the zoonotic swine influenza A virus (swIAV), a potential pandemic-causing agent, continues to be an urgent global health concern. Commercially available vaccines provide suboptimal cross-protectio
Externí odkaz:
https://doaj.org/article/89f51606ed564e20ae4202e634a85889
Autor:
Veerupaxagouda Patil, Juan F. Hernandez-Franco, Ganesh Yadagiri, Dina Bugybayeva, Sara Dolatyabi, Ninoshkaly Feliciano-Ruiz, Jennifer Schrock, Raksha Suresh, Juliette Hanson, Hadi Yassine, Harm HogenEsch, Gourapura J. Renukaradhya
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1707 (2023)
Swine influenza A viruses (SwIAVs) are pathogens of both veterinary and medical significance. Intranasal (IN) vaccination has the potential to reduce flu infection. We investigated the efficacy of split SwIAV H1N2 antigens adsorbed with a plant origi
Externí odkaz:
https://doaj.org/article/29fca6a7c4094a39a676bd61f5754ed2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent studies have shown that corn-derived cationic α-D-glucan nanoparticles, known as Nano-11, significantly increase the immune response when used as a vaccine adjuvant in mice and in pigs. Furthermore, the nanoparticles can be formulated with ot
Externí odkaz:
https://doaj.org/article/264617f6359647b88f7cd2daba7e3bcc
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1884 (2023)
Aluminum-based adjuvants will continue to be a key component of currently approved and next generation vaccines, including important combination vaccines. The widespread use of aluminum adjuvants is due to their excellent safety profile, which has be
Externí odkaz:
https://doaj.org/article/1cd8db26f020430783dacf6cd2962fbd
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Nanoparticles (NPs) are increasingly used as efficient vaccine antigen-delivery platforms and vaccine adjuvants. Alpha (α)-D-glucans are polysaccharide polymers found in plants, animals, and microbes. Phytoglycogen (PG) is a densely branched dendrim
Externí odkaz:
https://doaj.org/article/3a913f37f8474bb4b61ef7b5a4aa17c2
Autor:
Abhishek Datta, Juan F. Hernandez-Franco, Sungtae Park, Matthew R. Olson, Harm HogenEsch, Shankar Thangamani
Publikováno v:
Journal of Fungi, Vol 8, Iss 6, p 610 (2022)
Invasive Candida albicans (CA) infections often arise from the intestine and cause life-threatening infections in immunocompromised individuals. The role of gut commensal microbiota, metabolites, and host factors in the regulation of CA colonization
Externí odkaz:
https://doaj.org/article/4f38bb666fc74255b1348d2b843aaa5f