Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Harm C. den Boer"'
Autor:
Marion T. J. van den Bosch, Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Chantal L. Duurland, Rianne Biemans, Ludwig J. Dubois, Laurens A. H. van Pinxteren, Roel Q. J. Schaapveld, Michel Janicot
Publikováno v:
Frontiers in Drug Discovery, Vol 3 (2023)
As cancer is a multifactorial disease, the multimodal action of microRNAs makes them an attractive tool for novel therapeutic approaches. The tumor suppressive miR-7-5p has been shown to act on many aspects of oncogenesis, including cell proliferatio
Externí odkaz:
https://doaj.org/article/39e32167fc4c42c8971d2b5dfc2308e8
Autor:
Marion T.J. van den Bosch, Sanaz Yahyanejad, Mir Farshid Alemdehy, Bryony J. Telford, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Marieke Stegink, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 1161-1171 (2021)
Emerging data show that microRNA 193a-3p (miR-193a-3p) has a suppressive role in many cancers and is often downregulated in tumors, as compared to surrounding normal tissues. Therefore, mimics of miR-193a-3p could be used as an attractive therapeutic
Externí odkaz:
https://doaj.org/article/1437daaa0d744e4094d585ba636043d3
Autor:
Sanaz Yahyanejad, Harm C. den Boer, Marion T.J. van den Bosch, Laurens Adrianus Hendricus Van Pinxteren, Rogier M. Vos, Michel Janicot, Bryony J. Telford, Roel Q.J. Schaapveld, Thijs de Gunst, Mir Farshid Alemdehy, Marieke Stegink
Publikováno v:
Oncotarget
Compelling evidence demonstrates that miR-193a-3p is a tumor suppressor microRNA in many cancer types, and its reduced expression is linked to cancer initiation and progression, metastasis, and therapy resistance. However, its mechanism of action is
Autor:
Thijs de Gunst, Sanaz Yahyanejad, Marieke Stegink, Marion T.J. van den Bosch, Rogier M. Vos, Harm C. den Boer, Laurens Adrianus Hendricus Van Pinxteren, Mir Farshid Alemdehy, Roel Q.J. Schaapveld, Bryony J. Telford, Michel Janicot
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 1161-1171 (2021)
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 1161-1171 (2021)
Emerging data show that microRNA 193a-3p (miR-193a-3p) has a suppressive role in many cancers and is often downregulated in tumors, as compared to surrounding normal tissues. Therefore, mimics of miR-193a-3p could be used as an attractive therapeutic
Autor:
Harm C. den Boer, Farshid Alemdehy, Bryony J. Telford, Debbie Robbrecht, Nuria Kotecki, Laurens Adrianus Hendricus Van Pinxteren, Sanaz Yahyanejad, Marion T.J. van den Bosch, Karlijn Kroon, Frans L. Opdam, Thijs de Gunst, Rogier M. Vos, Michiel Strijbos, Michel Janicot, Roel Q.J. Schaapveld
Publikováno v:
Journal of Clinical Oncology. 39:TPS2666-TPS2666
TPS2666 Background: MicroRNAs (miR) are naturally-occurring small non-coding RNA molecules involved in the regulation of gene expression and their dysregulation plays a fundamental role in several pathological conditions including cancer. The miR-193
Autor:
Sanaz Yahyanejad, Bryony J. Telford, Iman J. Schultz, Michel Janicot, Monica Raimo, Harm C. den Boer, Thijs de Gunst, Rogier M. Vos, Roel Q.J. Schaapveld, Laurens Adrianus Hendricus Van Pinxteren
Publikováno v:
Cancer Research. 78:4405-4405
MicroRNAs (miRNAs) are a family of small, non-coding RNAs and serve as small snippets of genetic material that regulate gene expression. As a result, miRNAs modulate a wide range of biological processes including; cell cycle control and apoptosis, ce