Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Harley Y. Tse"'
Autor:
Kevin Yee-Bien Tse, Ayelet eGonen, John eSidney, Hui eOuyang, Joseph L Witztum, Alessandro eSette, Harley Y Tse, Klaus eLey
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Background: Subsets of CD4+ T-cells have been proposed to serve differential roles in the development of atherosclerosis. Some T-cell types are atherogenic (T-helper type 1), while others are thought to be protective (regulatory T-cells). Lineage com
Externí odkaz:
https://doaj.org/article/ae5dc9697b3e49c0a98abb802771866c
Publikováno v:
Cell Mol Immunol
Autor:
Matthew D. Fountain, Gilda G. Hillman, Natalie L Smith, Joseph T. Rakowski, Laura A McLellan, Harley Y. Tse, Brian Loughery
Publikováno v:
Int J Radiat Biol
PURPOSE: Vascular damage and inflammation are limiting toxic effects of lung cancer radiotherapy, which lead to pneumonitis and pulmonary fibrosis. We have demonstrated that soy isoflavones (SIF) mitigate these toxic effects at late time points after
Autor:
Rajesh Kumar Soni, Takahiro Yamazaki, Harley Y. Tse, Karthik Ramesh, Marco Viganò, Tsai Wanxia Li, Lorenzo Galluzzi, Lawrence J. Stern, Austin M. Graves, Laura Santambrogio, Massimo Gadina, Maria Pia Negroni, Hei Jung Kim, Paul A. Roche, Sangeetha Thangaswamy, Kateryna Morozova, Lisa K. Denzin, Padma P. Nanaware, Cristina C. Clement
Publikováno v:
Immunity
Summary Hyperglycemia and hyperlipidemia are often observed in individuals with type II diabetes (T2D) and related mouse models. One dysmetabolic biochemical consequence is the non-enzymatic reaction between sugars, lipids, and proteins, favoring pro
Autor:
Carmen Sánchez-Torres, Roberto Romero, Valeria Garcia-Flores, Yi Xu, Harley Y. Tse, Sonia S. Hassan, Nardhy Gomez-Lopez, Adi L. Tarca, Yaozhu Leng, Derek Miller, Chaur-Dong Hsu, Bogdan Done, Jose Galaz, Marcia Arenas-Hernandez
Publikováno v:
Cell reports
SUMMARY Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy; however, their role later in gestation is poorly understood. Herein, we report that functional Tregs are reduced at the maternal-fetal interface in a subse
Autor:
Harley Y. Tse, Paul C. Montgomery, William W. Cruikshank, Robert P. Lisak, Dusanka S Skundric
Publikováno v:
Cytokine. 75:234-248
Cytokines are pleiotropic soluble mediators of cellular functions. Cytokines are critical in immune pathogenesis of human diseases, including autoimmune CD4(+) T cell mediated chronic inflammatory, demyelinating and neurodegenerative diseases of the
T-Cells Specific for a Self-Peptide of ApoB-100 Exacerbate Aortic Atheroma in Murine Atherosclerosis
Autor:
Daniel T. Eitzman, Kevin Tse, Ryan Thummel, Raghavendar R. Thipparthi, Paul C. Montgomery, Michael K. Shaw, Harley Y. Tse, Kathryn C Welch, Xiaoqing Zhao
Publikováno v:
Frontiers in Immunology
On the basis of mouse I-Ab binding motifs, two sequences of the murine apolipoprotein ApoB-100, mApoB1003501-3515 (designated P3) and mApoB-100978-992 (designated P6), were found to be immunogenic. In this report, we show that P6 is also atherogenic.
Publikováno v:
International Immunology. 25:615-622
Atherosclerosis is a chronic inflammatory disease of the artery wall. Atherosclerotic lesions contain monocytes, macrophages, smooth muscle cells and T lymphocytes. Here, we review the role of T-lymphocyte subsets in atherosclerosis. Among CD4+ T cel
Publikováno v:
Glia. 61:192-209
Multiple sclerosis is a sexually dimorphic (SD) disease that causes oligodendrocyte death, but SD of glial cells is poorly studied. Here, we analyze SD of neural progenitors in 6–8 weeks and 6–8 months normal C57BL/6, SJL/J, and BALB/c mice in th
Publikováno v:
Journal of Neuroimmunology. 230:26-32
Earlier studies showed that donor T cells that initiated a murine adoptive EAE persisted in the CNS of the recipients throughout the subsequent relapsing cycles. To clarify the functions of the persistent donor T cells in EAE relapsing disease, anti-