Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Harley L, Worthy"'
Autor:
Simone A. De Rose, Michail N. Isupov, Harley L. Worthy, Christina Stracke, Nicholas J. Harmer, Bettina Siebers, Jennifer A. Littlechild, The HotSolute consortium, Christopher Bräsen, Benjamin Meyer, Simone Antonio De Rose, Jennifer Ann Littlechild, Elizaveta Bonch-Osmolovskaya, Sergey Gavrilov, Ilya Kublanov, Daniela Monti, Erica Ferrandi, Eleonora Dore, Felix Müller, Jacky Snoep
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The enzyme cyclic di-phosphoglycerate synthetase that is involved in the production of the osmolyte cyclic 2,3-diphosphoglycerate has been studied both biochemically and structurally. Cyclic 2,3-diphosphoglycerate is found exclusively in the hyperthe
Externí odkaz:
https://doaj.org/article/c43883716fda42c0bf71faf709f2430c
Autor:
Nehad Noby, Husam Sabah Auhim, Samuel Winter, Harley L. Worthy, Amira M. Embaby, Hesham Saeed, Ahmed Hussein, Christopher R. Pudney, Pierre J. Rizkallah, Stephen A. Wells, D. Dafydd Jones
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Here we determined the structure of a cold active family IV esterase (EstN7) cloned from Bacillus cohnii strain N1. EstN7 is a dimer with a classical α/β hydrolase fold. It has an acidic surface that is thought to play a role in cold-adaption by re
Externí odkaz:
https://doaj.org/article/742a9bfe43b248879d57a96a80adc331
Autor:
Rachel L. Johnson, Hayley G. Blaber, Tomas Evans, Harley L. Worthy, Jacob R. Pope, D. Dafydd Jones
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The formation of protein complexes is central to biology, with oligomeric proteins more prevalent than monomers. The coupling of functionally and even structurally distinct protein units can lead to new functional properties not accessible by monomer
Externí odkaz:
https://doaj.org/article/5fc1cc52946046d5a53248b0cc84651c
Autor:
Jacob R. Pope, Rachel L. Johnson, W. David Jamieson, Harley L. Worthy, Senthilkumar Kailasam, Rochelle D. Ahmed, Ismail Taban, Husam Sabah Auhim, Daniel W. Watkins, Pierre J. Rizkallah, Oliver K. Castell, D. Dafydd Jones
Publikováno v:
Advanced Science, Vol 8, Iss 1, Pp n/a-n/a (2021)
Abstract Fluorescent proteins (FPs) are commonly used in pairs to monitor dynamic biomolecular events through changes in proximity via distance dependent processes such as Förster resonance energy transfer (FRET). The impact of FP association is ass
Externí odkaz:
https://doaj.org/article/7938b9fd96124ed0a636bbaf8e40a461
Autor:
Krithika Ramakrishnan, Rachel L. Johnson, Samuel D. Winter, Harley L. Worthy, Christopher Thomas, Diana C. Humer, Oliver Spadiut, Sarah H. Hindson, Stephen Wells, Andrew H. Barratt, Georgina E. Menzies, Christopher R. Pudney, D. Dafydd Jones
Publikováno v:
The FEBS Journal.
Autor:
null Krithika Ramakrishnan, null Rachel L. Johnson, null Samuel D. Winter, null Harley L. Worthy, null Christopher Thomas, null Diana C. Humer, null Oliver Spadiut, null Sarah H. Hindson, null Stephen Wells, null Andrew H. Barratt, null Georgina E. Menzies, null Christopher R. Pudney, null D. Dafydd Jones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce83f8379f1bab935c06bbb0d3205d8b
https://doi.org/10.1111/febs.16783/v3/response1
https://doi.org/10.1111/febs.16783/v3/response1
Autor:
Harley L. Worthy, Lainey J. Williamson, Husam Sabah Auhim, Stephen H. Leppla, Inka Sastalla, D. Dafydd Jones, Pierre J. Rizkallah, Colin Berry
Publikováno v:
Toxins, Vol 13, Iss 4, p 253 (2021)
The Hbl toxin is a three-component haemolytic complex produced by Bacillus cereus sensu lato strains and implicated as a cause of diarrhoea in B. cereus food poisoning. While the structure of the HblB component of this toxin is known, the structures
Externí odkaz:
https://doaj.org/article/b0dc8e12acd44a729c284ab42d0a7198
Autor:
Krithika Ramakrishnan, Rachel L. Johnson, Sam D. Winter, Harley L. Worthy, Chris Thomas, Diana Humer, Oliver Spadiut, Sarah H. Hindson, Stephen Wells, Andrew H. Barratt, Georgina E. Menzies, Christopher R. Pudney, D. Dafydd Jones
Glycosylation is the most prevalent protein post-translational modification, with a quarter of glycosylated proteins having enzymatic properties. Yet the full impact of glycosylation on the protein structure-function relationship, especially in enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fc9872f8aca3bc8d7fc4e6fc6bd453
https://doi.org/10.1101/2022.09.23.509167
https://doi.org/10.1101/2022.09.23.509167
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbd4289a5e47312f9755008bdfd0d29
https://doi.org/10.1007/978-1-0716-2667-2_5
https://doi.org/10.1007/978-1-0716-2667-2_5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2564
Fluorescent proteins have revolutionized cell biology and cell imaging through their use as genetically encoded tags. Structural biology has been pivotal in understanding how their unique fluorescent properties manifest through the formation of the c