Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Harley H McAdams"'
Autor:
Beat Christen, Eduardo Abeliuk, John M Collier, Virginia S Kalogeraki, Ben Passarelli, John A Coller, Michael J Fero, Harley H McAdams, Lucy Shapiro
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-7 (2011)
Abstract Caulobacter crescentus is a model organism for the integrated circuitry that runs a bacterial cell cycle. Full discovery of its essential genome, including non‐coding, regulatory and coding elements, is a prerequisite for understanding the
Externí odkaz:
https://doaj.org/article/6a0a5ce7d79e41e58ad3743409109751
Autor:
Bo Zhou, Jared M Schrader, Virginia S Kalogeraki, Eduardo Abeliuk, Cong B Dinh, James Q Pham, Zhongying Z Cui, David L Dill, Harley H McAdams, Lucy Shapiro
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004831 (2015)
Each Caulobacter cell cycle involves differentiation and an asymmetric cell division driven by a cyclical regulatory circuit comprised of four transcription factors (TFs) and a DNA methyltransferase. Using a modified global 5' RACE protocol, we globa
Externí odkaz:
https://doaj.org/article/5d8969144c244a3fbe5a3b63edbe57a3
Autor:
Jared M Schrader, Bo Zhou, Gene-Wei Li, Keren Lasker, W Seth Childers, Brandon Williams, Tao Long, Sean Crosson, Harley H McAdams, Jonathan S Weissman, Lucy Shapiro
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004463 (2014)
Caulobacter crescentus undergoes an asymmetric cell division controlled by a genetic circuit that cycles in space and time. We provide a universal strategy for defining the coding potential of bacterial genomes by applying ribosome profiling, RNA-seq
Externí odkaz:
https://doaj.org/article/264f9539d190402cb77c3f98f1cf6fa3
Autor:
Harley H. McAdams, Keren Lasker, Lucy Shapiro, David L. Dill, Yifei Men, Jared M. Schrader, Tyler Marshik
Publikováno v:
Nucleic Acids Research
Caulobacter crescentus is a premier model organism for studying the molecular basis of cellular asymmetry. The Caulobacter community has generated a wealth of high-throughput spatiotemporal databases including data from gene expression profiling expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1459c4150ec7fc1874846ccd7bfaa913
https://doi.org/10.1093/nar/gkv1050
https://doi.org/10.1093/nar/gkv1050
Autor:
Jonathan S. Weissman, W. Seth Childers, Adam M. Perez, Gene-Wei Li, Harley H. McAdams, Lucy Shapiro, Jared M. Schrader
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Progression of the Caulobacter cell cycle requires temporal and spatial control of gene expression, culminating in an asymmetric cell division yielding distinct daughter cells. To explore the contribution of translational control, RNA-seq and ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e711ddbda86675f428733777eaebeee
https://doi.org/10.1073/pnas.1614795113
https://doi.org/10.1073/pnas.1614795113
Autor:
Harley H. McAdams, Mohammed AlQuraishi
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 81:426-442
The energetics of protein-DNA interactions are often modeled using so-called statistical potentials, that is, energy models derived from the atomic structures of protein-DNA complexes. Many statistical protein-DNA potentials based on differing theore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e1b55b92e15db110ece3da8cf680602
https://doi.org/10.1002/prot.24201
https://doi.org/10.1002/prot.24201
Autor:
Harley H. McAdams, Sun Hae Hong
Publikováno v:
Molecular Microbiology. 82:1349-1358
Summary Upon initiating replication of the Caulobacter chromosome, one copy of the parS centromere remains at the stalked pole; the other moves to the distal pole. We identified the segregation dynamics and compaction characteristics of newly replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10df3d1a3adfa906a3d388f5529878c5
https://doi.org/10.1111/j.1365-2958.2011.07899.x
https://doi.org/10.1111/j.1365-2958.2011.07899.x
Autor:
Mohammed AlQuraishi, Harley H. McAdams
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14819-14824
Compressed sensing has revolutionized signal acquisition, by enabling complex signals to be measured with remarkable fidelity using a small number of so-called incoherent sensors. We show that molecular interactions, e.g., protein–DNA interactions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3523d7dc41626d8d996c1178d321bd
https://doi.org/10.1073/pnas.1106460108
https://doi.org/10.1073/pnas.1106460108
Autor:
Lucy Shapiro, Harley H. McAdams, Michael J. Fero, Eduardo Abeliuk, Sun Hae Hong, Yi Chun Yeh, Erin D. Goley
Publikováno v:
Molecular Microbiology. 80:1680-1698
Cytokinesis in Gram-negative bacteria is mediated by a multiprotein machine (the divisome) that invaginates and remodels the inner membrane, peptidoglycan and outer membrane. Understanding the order of divisome assembly would inform models of the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad3e6421aa053b5c1df4ac5e8887eb7
https://doi.org/10.1111/j.1365-2958.2011.07677.x
https://doi.org/10.1111/j.1365-2958.2011.07677.x
Autor:
Lucy Shapiro, Harley H. McAdams
Publikováno v:
Journal of Molecular Biology. 409:28-35
The control circuitry that directs and paces Caulobacter cell cycle progression involves the entire cell operating as an integrated system. This control circuitry monitors the environment and the internal state of the cell, including the cell topolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e56677f59b769d3f562bafdbfaa3faf
https://doi.org/10.1016/j.jmb.2011.02.041
https://doi.org/10.1016/j.jmb.2011.02.041