Zobrazeno 1 - 10
of 881
pro vyhledávání: '"Harley, I."'
Autor:
Li, Shanpeng, Telesca, Donatello, Kornblum, Harley I., Nathanson, David, Pajonk, Frank, Cui, Elvis Han, Palmer, Joycelynne, Li, Gang
In cancer research, leveraging patient-derived xenografts (PDXs) in pre-clinical experiments is a crucial approach for assessing innovative therapeutic strategies. Addressing the inherent variability in treatment response among and within individual
Externí odkaz:
http://arxiv.org/abs/2404.08927
Autor:
Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-14 (2024)
Abstract Histone deacetylases (HDACs) have a wide range of targets and can rewire both the chromatin and lipidome of cancer cells. In this study, we show that valproic acid (VPA), a brain penetrant anti-seizure medication and histone deacetylase inhi
Externí odkaz:
https://doaj.org/article/ecf370d8942a4622b169a6b1429e57e4
Autor:
Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f17ac9f48872451c8adf495dc087b9f1
Autor:
Sohrabi, Alireza, Lefebvre, Austin E.Y.T., Harrison, Mollie J., Condro, Michael C., Sanazzaro, Talia M., Safarians, Gevick, Solomon, Itay, Bastola, Soniya, Kordbacheh, Shadi, Toh, Nadia, Kornblum, Harley I., Digman, Michelle A., Seidlits, Stephanie K.
Publikováno v:
In Cell Reports 31 October 2023 42(10)
Autor:
Alireza Sohrabi, Austin E.Y.T. Lefebvre, Mollie J. Harrison, Michael C. Condro, Talia M. Sanazzaro, Gevick Safarians, Itay Solomon, Soniya Bastola, Shadi Kordbacheh, Nadia Toh, Harley I. Kornblum, Michelle A. Digman, Stephanie K. Seidlits
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113175- (2023)
Summary: The mechanical properties of solid tumors influence tumor cell phenotype and the ability to invade surrounding tissues. Using bioengineered scaffolds to provide a matrix microenvironment for patient-derived glioblastoma (GBM) spheroids, this
Externí odkaz:
https://doaj.org/article/d2250eca7fe7426383653643a3dc60db
Autor:
Sree Deepthi Muthukrishnan, Riki Kawaguchi, Pooja Nair, Rachna Prasad, Yue Qin, Maverick Johnson, Qing Wang, Nathan VanderVeer-Harris, Amy Pham, Alvaro G. Alvarado, Michael C. Condro, Fuying Gao, Raymond Gau, Maria G. Castro, Pedro R. Lowenstein, Arjun Deb, Jason D. Hinman, Frank Pajonk, Terry C. Burns, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Therapeutic stress induces phenotypic plasticity in glioma stem cells although the mechanisms underlying this remain poorly understood. Here, the authors show that P300 mediates the radiation-induced vascular-like conversion of glioma stem cells to p
Externí odkaz:
https://doaj.org/article/2f813af486a84bc6939ddacebcf2e7f8
Autor:
Ghochani, Yasmin, Muthukrishnan, Sree Deepthi, Sohrabi, Alireza, Kawaguchi, Riki, Condro, Michael C., Bastola, Soniya, Gao, Fuying, Qin, Yue, Mottahedeh, Jack, Iruela-Arispe, M. Luisa, Rao, Nagesh, Laks, Dan R., Liau, Linda M., Mathern, Gary W., Goldman, Steven A., Carmichael, S. Thomas, Nakano, Ichiro, Coppola, Giovanni, Seidlits, Stephanie K., Kornblum, Harley I.
Publikováno v:
In Cell Reports 18 October 2022 41(3)
Autor:
Watanabe, Momoko, Buth, Jessie E., Haney, Jillian R., Vishlaghi, Neda, Turcios, Felix, Elahi, Lubayna S., Gu, Wen, Pearson, Caroline A., Kurdian, Arinnae, Baliaouri, Natella V., Collier, Amanda J., Miranda, Osvaldo A., Dunn, Natassia, Chen, Di, Sabri, Shan, Torre-Ubieta, Luis de la, Clark, Amander T., Plath, Kathrin, Christofk, Heather R., Kornblum, Harley I., Gandal, Michael J., Novitch, Bennett G.
Publikováno v:
In Stem Cell Reports 11 October 2022 17(10):2220-2238
Autor:
Shi, Diana D., Savani, Milan R., Levitt, Michael M., Wang, Adam C., Endress, Jennifer E., Bird, Cylaina E., Buehler, Joseph, Stopka, Sylwia A., Regan, Michael S., Lin, Yu-Fen, Puliyappadamba, Vinesh T., Gao, Wenhua, Khanal, Januka, Evans, Laura, Lee, Joyce H., Guo, Lei, Xiao, Yi, Xu, Min, Huang, Bofu, Jennings, Rebecca B., Bonal, Dennis M., Martin-Sandoval, Misty S., Dang, Tammie, Gattie, Lauren C., Cameron, Amy B., Lee, Sungwoo, Asara, John M., Kornblum, Harley I., Mak, Tak W., Looper, Ryan E., Nguyen, Quang-De, Signoretti, Sabina, Gradl, Stefan, Sutter, Andreas, Jeffers, Michael, Janzer, Andreas, Lehrman, Mark A., Zacharias, Lauren G., Mathews, Thomas P., Losman, Julie-Aurore, Richardson, Timothy E., Cahill, Daniel P., DeBerardinis, Ralph J., Ligon, Keith L., Xu, Lin, Ly, Peter, Agar, Nathalie Y.R., Abdullah, Kalil G., Harris, Isaac S., Kaelin, William G., Jr., McBrayer, Samuel K.
Publikováno v:
In Cancer Cell 12 September 2022 40(9):939-956
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