Design and development of a machine-learning-driven opioid overdose risk prediction tool integrated in electronic health records in primary care settings

Autor: Khoa Nguyen, Debbie L. Wilson, Julie Diiulio, Bradley Hall, Laura Militello, Walid F. Gellad, Christopher A. Harle, Motomori Lewis, Siegfried Schmidt, Eric I. Rosenberg, Danielle Nelson, Xing He, Yonghui Wu, Jiang Bian, Stephanie A. S. Staras, Adam J. Gordon, Jerry Cochran, Courtney Kuza, Seonkyeong Yang, Weihsuan Lo-Ciganic

Publikováno v: Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-14 (2024)

Abstract Background Integrating advanced machine-learning (ML) algorithms into clinical practice is challenging and requires interdisciplinary collaboration to develop transparent, interpretable, and ethically sound clinical decision support (CDS) to

Externí odkaz: https://doaj.org/article/f82f1a8f2e584031b422e4a83946c927

Acceptance of Automated Social Risk Scoring in the Emergency Department: Clinician, Staff, and Patient Perspectives

Autor: Olena Mazurenko, Adam T. Hirsh, Christopher A. Harle, Cassidy McNamee, Joshua R. Vest

Publikováno v: Western Journal of Emergency Medicine, Vol 25, Iss 4, Pp 614-623 (2024)

Introduction: Healthcare organizations are under increasing pressure from policymakers, payers, and advocates to screen for and address patients’ health-related social needs (HRSN). The emergency department (ED) presents several challenges to HRSN

Externí odkaz: https://doaj.org/article/95810429c81a4da9b5c6c80602765f85

Protocol for a phase 3, randomised, active-control study of four-factor prothrombin complex concentrate versus frozen plasma in bleeding adult cardiac surgery patients requiring coagulation factor replacement: the LEX-211 (FARES-II) trial

Autor: Éric Dumont, Lusine Abrahamyan, Stuart Mccluskey, Angela Jerath, Humara Poonawala, Andrew Stevens, Jeannie Callum, Alan Tinmouth, Daniel Wong, Gianluigi Bisleri, Tarit Saha, David Mazer, Hilary Grocott, Jane Yang, Jeff Kinney, Yoan Lamarche, Damon Scales, George Tomlinson, Fuad Moussa, Andrew Shih, Michelle Zeller, Melanie Tokessy, Keyvan Karkouti, Vivek Rao, Summer Syed, Lilia Kaustov, Sophia Wong, Lani Lieberman, Kamrouz Ghadimi, Philippe Demers, Penny Johnson, Jerrold H Levy, Justyna Bartoszko, Miki Peer, Michael Law, Michelle Wong, Mackenzie Quantz, Antoine Rochon, Fraser Rubens, Shagun Jain, Yulia Lin, Katerina Pavenski, Deep Grewal, Deborah DuMerton, Darrin Payne, Saba Ansari, Robert Mayer, Rebecca Randall, Aftab Malik, Bethany Smethurst, Laura Molnar, Angela Sirosky-Yanyk, Mark Peterson, Christopher Harle, Etienne Couture, Diem Tran, Cristina Solomon, Sigurd Knaub, Kenichi A Tanaka, Blaine Achen, Sukhpal Brar, Matthew Coley, Dana Devine, Alana Flexman, Camila Machado de Souza, Maria Rosal Martins, Terri Sun, Rob Tanzola, Mathew Yan, Raffael Zamper, Jo Carrol, Nishanthi Liyanage, Simryn Selby, Reezanoor Kabir, Shelley Oliver, Alioska Escorcia, Susana Medic, Michelle Mozel, Ramanjot Kaur, Kelly Bizovie, Sarah Buchko, Raven Arly Gonzales, Korey Sutherland, Jenna Van Roekel, Alveena Babul, Ken Tanaka, Kofi Vandyck, Amir Butt, Hisako Okada, Robert Tanzola, Reegan Tod, Aiden Scholey, Wafaa Haider, Ester Cisneros-Aguilera, Alexandre Bergeron, Genevieve Belanger, Darren Mullane, Bevan Hughes, Sakara Hutspardol, Shirley Lim, Jian Mi, Debbie Kalar, Matthew Eang, Erick Lorenzana-Saldivar, Edward P Chen, Akash Gupta, Philip Lau, Pablo Perez D’Empaire, Chantal Armali, Amie Malkin, Connie Colavecchia, Harley Meirovich, Annie Bergeron, Francois Laforge, Kim Paradis, Nathalie Gagne, Marie Soleil Saillant, Marie-Claude Vézina, Olivier Royer, Marie-Ève Charest, Lee-Anne Fochesato, Yuxin Bai, Iqbal Jaffar, Nour Alhomsi, Janine Guevarra, Erin Jamula, Wan Chien (Betty) Hsu, Abbey Drew, Hakan Buyukdere, Drashtee Patel, Elizabeth Watt, Hadia Arabi Katbi, Kim Luciano, Amy Moorehead, Kamola Kasimova, Farzana Tasmin, Cielo Bingley, Victoria Barkley, Tob Reegan, Marianna Qu, Jessica Xiong, Sophie Robichaud, Christy Peterson, Manu Jairath, Mathew Tang, Jennita Aariaratnam, Leron DuMerton, Lucas Drew, Sahrish Masood, Toni Tidy, Elizabeth Krok

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Introduction Reduced thrombin generation is an important component of post cardiopulmonary bypass (CPB) coagulopathy. To replenish coagulation factors and enhance thrombin generation in bleeding surgical patients, frozen plasma (FP) and four-factor p

Externí odkaz: https://doaj.org/article/f4b23ce7268143bca04256dccb1c3cbf

Barriers, facilitators, and recommendations to increase the use of a clinical decision support tool for managing chronic pain in primary care

Autor: Cuadros, Pablo, McCord, Emma, McDonnell, Cara, Apathy, Nate C., Sanner, Lindsey, Adams, Meredith C.B., Mamlin, Burke W., Vest, Joshua R., Hurley, Robert W., Harle, Christopher A., Mazurenko, Olena

Publikováno v: In International Journal of Medical Informatics December 2024 192

Multi-model comparison of trends and controls of near-bed oxygen concentration on the northwest European continental shelf under climate change

Autor: G. Galli, S. Wakelin, J. Harle, J. Holt, Y. Artioli

Publikováno v: Biogeosciences, Vol 21, Pp 2143-2158 (2024)

We present an analysis of the evolution of near-bed oxygen in the next century in the northwest European continental shelf in a three-member ensemble of coupled physics–biogeochemistry models. The comparison between model results helps highlight th

Externí odkaz: https://doaj.org/article/0f0c6cbd34ed44f882b468549569dde2