Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale.

Autor: Imaz-Rosshandler I; Department of Haematology, University of Cambridge, Cambridge CB2 0RE, UK.; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK.; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Rode C; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK., Guibentif C; Department of Microbiology and Immunology, University of Gothenburg, 405 30 Gothenburg, Sweden., Harland LTG; Department of Haematology, University of Cambridge, Cambridge CB2 0RE, UK.; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Ton MN; Department of Haematology, University of Cambridge, Cambridge CB2 0RE, UK.; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Dhapola P; Division of Molecular Hematology, Lund Stem Cell Center, Lund University, 221 00 Lund, Sweden., Keitley D; Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK., Argelaguet R; Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK.; Altos Labs Cambridge Institute, Granta Park, Cambridge CB21 6GP, UK., Calero-Nieto FJ; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Nichols J; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Marioni JC; Wellcome Sanger Institute, Wellcome Genome Campus, Saffron Walden CB10 1SA, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Saffron Walden CB10 1SA, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK., de Bruijn MFTR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK., Göttgens B; Department of Haematology, University of Cambridge, Cambridge CB2 0RE, UK.; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK.

Publikováno v: Development (Cambridge, England) [Development] 2024 Feb 01; Vol. 151 (3). Date of Electronic Publication: 2024 Jan 31.

Eomesodermin governs the hemogenic competence of murine mesodermal progenitors

Autor: Harland, LTG

During mouse gastrulation pluripotent epiblast cells traverse the primitive streak (PS) and diversify into mesoderm and endoderm subtypes. The T-box transcription factor Eomesodermin (Eomes) is expressed during PS formation and is critical for the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::c89cd0a5bc6b72897f29a00c854a62b7
https://ora.ox.ac.uk/objects/uuid:c8ea52f5-fc46-4bff-be9c-cc75cce0a556

The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors.

Autor: Harland LTG; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Simon CS; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Senft AD; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Costello I; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Greder L; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Imaz-Rosshandler I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Göttgens B; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK., Marioni JC; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK.; Wellcome Sanger Institute, Cambridge, UK.; CRUK Cambridge Institute, University of Cambridge, Cambridge, UK., Bikoff EK; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Porcher C; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., de Bruijn MFTR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. marella.debruijn@imm.ox.ac.uk., Robertson EJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. elizabeth.robertson@path.ox.ac.uk.

Publikováno v: Nature cell biology [Nat Cell Biol] 2021 Jan; Vol. 23 (1), pp. 61-74. Date of Electronic Publication: 2021 Jan 08.

Associations between Human Papillomavirus Status, Weight Change, and Survival of Oropharyngeal Cancer Patients.

Autor: de Oliveira Faria, Sheilla¹, Hueniken, Katrina², Kunaratnam, Vijay³, Hui Huang, Shao^4,5, Goldstein, David⁵, Ringash, Jolie^4,5, Pun, Joanne⁶, Hope, Andrew⁴, Spreafico, Anna³, Xu, Wei², Howell, Doris⁷, Liu, Geoffrey³

Publikováno v: Nutrition & Cancer. 2023, Vol. 75 Issue 7, p1541-1550. 10p. 4 Charts, 2 Graphs.

Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC).

Autor: Fong, Pei Yuan¹ (AUTHOR), Tan, Sze Huey² (AUTHOR), Lim, Darren Wan Teck¹ (AUTHOR), Tan, Eng Huat¹ (AUTHOR), Ng, Quan Sing¹ (AUTHOR), Sommat, Kiattisa³ (AUTHOR), Tan, Daniel Shao Weng¹ (AUTHOR), Ang, Mei Kim¹ (AUTHOR) Ang.mei.kim@singhealth.com.sg

Publikováno v: PLoS ONE. 11/20/2019, Vol. 14 Issue 11, p1-18. 18p.