Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Harlan King"'
Autor:
Yingwei Chen, Eric A. Toth, Biao Ruan, Eun Jung Choi, Richard Simmerman, Yihong Chen, Yanan He, Ruixue Wang, Raquel Godoy-Ruiz, Harlan King, Gregory Custer, D. Travis Gallagher, David A. Rozak, Melani Solomon, Silvia Muro, David J. Weber, John Orban, Thomas R. Fuerst, Philip N. Bryan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Chen et al. describe a rational design of subtilisin mutants that degrade active RAS by cleaving a conserved sequence in switch 2. They further modified the active site to be dependent on a cofactor to generate high target specificity. Proteases engi
Externí odkaz:
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
Autor:
Ying Wu, Xianfeng Ma, Zhiyong Pan, Shiv D. Kale, Yi Song, Harlan King, Qiong Zhang, Christian Presley, Xiuxin Deng, Cheng-I Wei, Shunyuan Xiao
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract Background Powdery mildew (PM) is one of the most important and widespread plant diseases caused by biotrophic fungi. Notably, while monocot (grass) PM fungi exhibit high-level of host-specialization, many dicot PM fungi display a broad host
Externí odkaz:
https://doaj.org/article/556f3908bda3457f9fa9c8127f347f81
Autor:
John Orban, Yihong Chen, Yanan He, David J. Weber, Eun Jung Choi, Raquel Godoy-Ruiz, Biao Ruan, D. Travis Gallagher, Melani Solomon, Thomas R. Fuerst, Ruixue Wang, David A. Rozak, Gregory S. Custer, Philip N. Bryan, Harlan King, Silvia Muro, Eric A. Toth, Yingwei Chen, Richard Simmerman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
We describe the design, kinetic properties, and structures of engineered subtilisin proteases that degrade the active form of RAS by cleaving a conserved sequence in switch 2. RAS is a signaling protein that, when mutated, drives a third of human can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768ae163ddb6ebc0c904ea01793832d2
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
Autor:
Anna Liddle, Xuemin Wang, Shunyuan Xiao, Qiong Zhang, Liang Guo, Teun Munnik, Joshua J. Blakeslee, Jinshan Lin, Harlan King, Xianfeng Ma, Robert Berkey
Publikováno v:
Journal of Experimental Botany
Journal of Experimental Botany, 69(15), 3675-3688. Oxford University Press
Journal of Experimental Botany, 69(15), 3675-3688. Oxford University Press
Phospholipase Dδ (PLDδ) is involved in promoting basal, post-penetration resistance against powdery mildew through a potentially novel pathway(s) independent of EDS1/PAD4, SA, and JA, whereas PLDα1 negatively modulates this process.
Plants us
Plants us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4b4bdcef16d861120c6eedc5da8968
https://doi.org/10.1093/jxb/ery146
https://doi.org/10.1093/jxb/ery146
Autor:
Shiv D. Kale, Xiuxin Deng, Christian Presley, Cheng-I Wei, Shunyuan Xiao, Harlan King, Yi Song, Qiong Zhang, Ying Wu, Xianfeng Ma, Zhiyong Pan
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Background Powdery mildew (PM) is one of the most important and widespread plant diseases caused by biotrophic fungi. Notably, while monocot (grass) PM fungi exhibit high-level of host-specialization, many dicot PM fungi display a broad host range. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a500db0d75b46eb14e0a48e5645370a8
https://doi.org/10.1186/s12864-018-5069-z
https://doi.org/10.1186/s12864-018-5069-z
Autor:
Robert Berkey, Harlan King, Qiong Zhang, Dipti Bendigeri, Yi Zhang, Wenming Wang, Xianfeng Ma, Shunyuan Xiao, Zhiyong Pan, Ying-Qiang Wen
Publikováno v:
The Plant Cell. 25:4242-4261
The Arabidopsis thaliana RESISTANCE TO POWDERY MILDEW8.2 (RPW8.2) protein is specifically targeted to the extrahaustorial membrane (EHM) encasing the haustorium, or fungal feeding structure, where RPW8.2 activates broad-spectrum resistance against po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a4ae367ad5c57e035c76826ed692ab
https://doi.org/10.1105/tpc.113.117226
https://doi.org/10.1105/tpc.113.117226
Publikováno v:
Plant physiology. 173(1)
Upon penetration of the host cell wall, the powdery mildew fungus develops a feeding structure named the haustorium in the invaded host cell. Concomitant with haustorial biogenesis, the extrahaustorial membrane (EHM) is formed to separate the haustor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c503654a0b9d4f4f31e8b7ec4f38d550
https://pubmed.ncbi.nlm.nih.gov/27856916
https://pubmed.ncbi.nlm.nih.gov/27856916
Autor:
Shunyuan Xiao, Xing-Yao Xiong, Wenming Wang, Ling-Li Zhang, Florian Bittner, Harlan King, Qiong Zhang, Liqiang Tan, Nadine Schmidt, Ziniu Deng, Xianfeng Ma, Yinqiang Wen, Robert Berkey, Yi Zhang, Yue Li, Jiayue Feng
While plants produce reactive oxygen species (ROS) for stress signaling and pathogen defense, they need to remove excessive ROS induced during stress responses in order to minimize oxidative damage. How can plants fine-tune this balance and meet such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8311e234ff8b89ac26add8cf1c20d14
https://europepmc.org/articles/PMC4904670/
https://europepmc.org/articles/PMC4904670/
Publikováno v:
Virology. 396(1):135-142
The envelope glycoprotein (GP) of Ebolavirus (EBOV) mediates viral entry into host cells. Through mutagenesis, we and other groups reported that two phenylalanines at positions 88 and 159 of GP are critical for viral entry. However, it remains elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178f1a16a092e1f24ea0a46a8b054e74
Publikováno v:
Plant Physiology; Jan2017, Vol. 173 Issue 1, p600-613, 14p