Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Harlan D Caldwell"'
Autor:
Laszlo Kari, Lauren E Bakios, Morgan M Goheen, Leah N Bess, Heather S Watkins, Timothy R Southern, Lihua Song, William M Whitmire, Norma Olivares-Zavaleta, Harlan D Caldwell
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2248 (2013)
Chlamydia trachomatis is the etiological agent of trachoma the world's leading cause of infectious blindness. Here, we investigate whether protracted clearance of a primary infection in nonhuman primates is attributable to antigenic variation or rela
Externí odkaz:
https://doaj.org/article/16df5ed07cbd406f98ebb7f6ca4da816
Autor:
Addison G. DeBoer, Lei Lei, Chunfu Yang, Craig A. Martens, Sarah L. Anzick, Sophia Antonioli-Schmit, Robert J. Suchland, Grant McClarty, Harlan D. Caldwell, Daniel D. Rockey
Publikováno v:
Infection and Immunity.
All members of the family Chlamydiaceae have lipopolysaccharides (LPS) that possess a shared carbohydrate trisaccharide antigen, 3-deoxy- d -manno-oct-2-ulosonic acid (Kdo) that is functionally uncharacterized. A single gene, genus-specific epitope (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1faf7408b7b338b98419de563135598d
https://doi.org/10.1128/iai.00096-23
https://doi.org/10.1128/iai.00096-23
Autor:
Saba Firdous, Harlan D. Caldwell, Li Ma, David W. Dorward, Michael John Patton, Grant McClarty, Margery G. Smelkinson, Chunfu Yang, Lei Lei, Una Karanovic
Publikováno v:
mBio
mBio, Vol 12, Iss 3 (2021)
mBio, Vol 12, Iss 3 (2021)
Chlamydia are obligate intracellular Gram-negative bacteria distinguished by a unique developmental biology confined within a parasitophorous vacuole termed an inclusion. The chlamydial plasmid is a central virulence factor in the pathogenesis of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b967f1692fbfc3fc78e1d728c2d0eb
http://europepmc.org/articles/PMC8262877
http://europepmc.org/articles/PMC8262877
Autor:
Craig Martens, Michael Briones, Ian N. Moore, Yoichiro Iwakura, Masahiro Yamamoto, Chih-Yu Chen, Kiyoshi Takeda, Hua Su, Stacy M. Ricklefs, Chunfu Yang, Lei Lei, Grant McClarty, Gail L. Sturdevant, Kevin W. Bock, David W. Dorward, John W.Marshall Collins, Christine Bonner, Anuj K. Kashyap, Li Ma, Harlan D. Caldwell
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Chlamydia trachomatis infection causes severe inflammatory disease resulting in blindness and infertility. The pathophysiology of these diseases remains elusive but myeloid cell-associated inflammation has been implicated. Here we show NLRP3 inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca5cd91c56c4532f3326cf5fda2394c
https://pubmed.ncbi.nlm.nih.gov/34526512
https://pubmed.ncbi.nlm.nih.gov/34526512
Autor:
Harlan D. Caldwell, Grant McClarty, Laszlo Kari, Ian N. Moore, Chunfu Yang, Lei Lei, John H. Carlson, Kevin W. Bock, Li Ma, William M. Whitmire, Claire E. Couch, Christine Bonner
Publikováno v:
mBio
mBio, Vol 11, Iss 4 (2020)
mBio, Vol 11, Iss 4 (2020)
Chlamydia trachomatis can cause persistent infection that drives damaging inflammatory responses resulting in infertility and blindness. Little is known about chlamydial genes that cause persistence or factors that drive damaging pathology. In this w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3963c6f4b5ca230fc9d322be9e7a8f9d
https://pubmed.ncbi.nlm.nih.gov/32817110
https://pubmed.ncbi.nlm.nih.gov/32817110
Autor:
Michael Briones, Grant McClarty, Li Ma, Chunfu Yang, Lei Lei, Michael John Patton, Janice Chiou, Harlan D. Caldwell
Publikováno v:
mBio
mBio, Vol 10, Iss 2, p e00595-19 (2019)
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00595-19 (2019)
mBio, Vol 10, Iss 2 (2019)
Chlamydia trachomatis is the most common bacterial cause of sexually transmitted infections (STI). C. trachomatis STI are commonly asymptomatic, implying a pathogenic strategy for the evasion of innate inflammatory immune responses, a paradox as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e4604b41cd2911a583ab8d6d929db7
http://europepmc.org/articles/PMC6479002
http://europepmc.org/articles/PMC6479002
Autor:
Yvonne T. Cosgrove Sweeney, Gail L. Sturdevant, Laszlo Kari, Chunfu Yang, Dorothy L. Patton, Harlan D. Caldwell, Linda Cles, Audrey Baldessari
Publikováno v:
Infection and Immunity
The Chlamydia trachomatis plasmid and inclusion membrane protein CT135 are virulence factors in the pathogenesis of murine female genital tract infection. To determine if these virulence factors play a similar role in female nonhuman primates, we inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59a8d7b0d39246faa72651ff03e5b27
http://europepmc.org/articles/PMC5913843
http://europepmc.org/articles/PMC5913843
Autor:
Michael John Patton, Chih-Yu Chen, Chunfu Yang, Stuart McCorrister, Chris Grant, Garrett Westmacott, Xin-Yong Yuan, Estela Ochoa, Robert Fariss, William M. Whitmire, John H. Carlson, Harlan D. Caldwell, Grant McClarty, Raphael Valdivia, Alan G. Barbour
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
mBio
mBio, Vol 9, Iss 1, p e02164-17 (2018)
mBio
mBio, Vol 9, Iss 1, p e02164-17 (2018)
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease. C. trachomatis isolates are classified into 2 biovars—lymphogranuloma venereum (LGV) and trachoma—which are dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c3ce19bf065cf99bd532f4e349d252
https://journals.asm.org/doi/10.1128/mBio.02164-17
https://journals.asm.org/doi/10.1128/mBio.02164-17
Autor:
William M. Whitmire, Ian N. Moore, Chunfu Yang, Gail L. Sturdevant, Kevin W. Bock, Harlan D. Caldwell
Publikováno v:
Infection and Immunity. 85
We studied infection and immunity of hysterectomized mice infected with Chlamydia muridarum and Chlamydia trachomatis to determine if there were differences between these species in their ability to infect vaginal squamous epithelial cells in vivo in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c52b23a418a54e1b821e241e5ef079
https://doi.org/10.1128/iai.00197-17
https://doi.org/10.1128/iai.00197-17
Autor:
Harlan D. Caldwell, Michael Briones, Timothy R. Southern, Jillian M Ilgenfritz, Christopher C. R. Grant, Grant McClarty, Christine Bonner, Claire E. Couch, Michael John Patton, Lihua Song, Gail L. Sturdevant, William M. Whitmire, Laszlo Kari, Pinzhao Hu, Chunfu Yang
Chlamydia trachomatis is an obligate intracellular pathogen characterized by a unique biphasic developmental cycle that alternates between infectious and non-infectious organisms. Chlamydial ChxR is a transcriptional activator that has been implicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01e1b9d012fc3562f8540e8ad21b695
https://europepmc.org/articles/PMC5974934/
https://europepmc.org/articles/PMC5974934/
