Výsledky vyhledávání - "Harkiranpreet Kaur Dhaliwal"

Local epidermal growth factor delivery using nanopillared chitosan–gelatin films for melanogenesis and wound healing

Autor: Sevde Altuntas, Harkiranpreet Kaur Dhaliwal, Ahmed Eid Radwan, Mansoor Amiji, Fatih Buyukserin

Publikováno v: Biomaterials Science. 11:181-194

Epidermal growth factor (EGF) is required for various regulations of skin tissue including wound healing; however, it has limited stability due to the physicochemical conditions of the wound milieu. The lack of functional EGF within the wound can cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4782308b3ab5f7038418d8fa7495264f
https://doi.org/10.1039/d2bm00836j

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Nanopillared Chitosan/Gelatin Films: A Biomimetic Approach for Improved Osteogenesis

Autor: Sevde Altuntas, Thomas J. Webster, Pınar Alpaslan, Harkiranpreet Kaur Dhaliwal, Mansoor M. Amiji, Fatih Buyukserin, Nicole J. Bassous, Ahmed E. Radwan

Publikováno v: ACS biomaterials scienceengineering. 5(9)

Biomimicry strategies, inspired from natural organization of living organisms, are being widely used in the design of nanobiomaterials. Particularly, nonlithographic techniques have shown immense potential in the facile fabrication of nanostructured

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d50f5a3cf51abb9537eb0ed0c04eef1
https://pubmed.ncbi.nlm.nih.gov/33417787

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Intranasal Delivery and Transfection of mRNA Therapeutics in the Brain Using Cationic Liposomes

Autor: Jonghan Kim, Mansoor M. Amiji, Harkiranpreet Kaur Dhaliwal, Yingfang Fan

Publikováno v: Molecular pharmaceutics. 17(6)

Nucleic acid-based therapeutics, including the use of messenger RNA (mRNA) as a drug molecule, has tremendous potential in the treatment of chronic diseases, such as age-related neurodegenerative diseases. In this study, we have developed a cationic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20b78c815b9d4a58ba11f09e5fe7fef
https://pubmed.ncbi.nlm.nih.gov/32365295

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Optimization of the Conditions for Plasmid DNA Delivery and Transfection with Self-Assembled Hyaluronic Acid-Based Nanoparticles

Autor: Mansoor M. Amiji, Hibah M. Aldawsari, Harkiranpreet Kaur Dhaliwal, Nabil A. Alhakamy, Zainy Mohammad Banjar, Bader M Aljaeid

Publikováno v: Molecular Pharmaceutics. 16:128-140

Polymeric systems have been extensively studied as polyelectrolyte complexes to enhance the cellular delivery and transfection efficiency of genetic materials, such as plasmid DNA (pDNA). Here, self-assembled nanoparticles were formulated by complexa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560427f99e5c7545fcf1c0596644f5dc
https://doi.org/10.1021/acs.molpharmaceut.8b00904

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Enhanced anti-angiogenic effects of bevacizumab in glioblastoma treatment upon intranasal administration in polymeric nanoparticles

Autor: Bruno Sarmento, Florence Gattacceca, Harkiranpreet Kaur Dhaliwal, Mansoor M. Amiji, Flávia Sousa

Publikováno v: Journal of Controlled Release
Journal of Controlled Release, 2019, 309, pp.37-47. ⟨10.1016/j.jconrel.2019.07.033⟩
Journal of Controlled Release, Elsevier, 2019, 309, pp.37-47. ⟨10.1016/j.jconrel.2019.07.033⟩

International audience; Glioblastoma multiforme (GBM) is one of the most aggressive cancers, where the aggressiveness of tumor has been associated to its high vascularization rate. Bevacizumab (Avastin®), an anti-angiogenic monoclonal antibody, has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f4afce8bda09549a2ff0a6227d7370
https://hal.science/hal-02533340

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Local Immunomodulation Using an Adhesive Hydrogel Loaded with miRNA-Laden Nanoparticles Promotes Wound Healing

Autor: Nasim Annabi, Mansoor M. Amiji, Reza Abdi, Bahram Saleh, Roberto Portillo-Lara, Harkiranpreet Kaur Dhaliwal, Ehsan Shirzaei Sani

Publikováno v: Small (Weinheim an der Bergstrasse, Germany), vol 15, iss 36
Small

Chronic wounds are characterized by impaired healing and uncontrolled inflammation, which compromise the protective role of the immune system and may lead to bacterial infection. Upregulation of miR-223 microRNAs (miRNAs) shows driving of the polariz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e919db551b478e9bb2e08e1e082d8d93
https://escholarship.org/uc/item/7zv3889k

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High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics

Autor: Bal Ram Singh, Kruti Patel, Raj Kumar, Nagarajan Thiruvanakarasu, Ghuncha Ambrin, Shouwei Cai, Harkiranpreet Kaur Dhaliwal

Botulinum neurotoxins (BoNTs) are the most toxic proteins known to cause flaccid muscle paralysis as a result of inhibition of neurotransmitter release from peripheral cholinergic synapses. BoNT type A (BoNT/A) is a 150 kDa protein consisting of two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49a86a98657000da31ac1f872cae22c
https://europepmc.org/articles/PMC5705016/

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