Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Haritha, Kunhiraman"'
Autor:
Menglang Yuan, Iqbal Mahmud, Keisuke Katsushima, Kandarp Joshi, Olivier Saulnier, Rudramani Pokhrel, Bongyong Lee, Wathsala Liyanage, Haritha Kunhiraman, Stacie Stapleton, Ignacio Gonzalez-Gomez, Rangaramanujam M. Kannan, Tanja Eisemann, Elayaraja Kolanthai, Sudipta Seal, Timothy J. Garrett, Saed Abbasi, Kimberly Bockley, Justin Hanes, Prem Chapagain, George Jallo, Robert J. Wechsler-Reya, Michael D. Taylor, Charles G. Eberhart, Animesh Ray, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator of cells that descen
Externí odkaz:
https://doaj.org/article/d02fc40d411f4baba42e490fbec01155
Autor:
Shubin W. Shahab, Christianna M. Roggeveen, Jiarong Sun, Haritha Kunhiraman, Leon F. McSwain, Kyle Juraschka, Sachin A. Kumar, Olivier Saulnier, Michael D. Taylor, Matthew Schniederjan, Robert W. Schnepp, Tobey J MacDonald, Anna Marie Kenney
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1784-1802 (2023)
Children with Group 3 medulloblastoma (G3 MB) have a very poor prognosis, and many do not survive beyond 5 years after diagnosis. A factor that may contribute to this is the lack of available targeted therapy. Expression of protein lin‐28 homolog B
Externí odkaz:
https://doaj.org/article/93a4f4cb469a4d629a58e2ccc4aa8c54
Autor:
Leon F. McSwain, Claire E. Pillsbury, Ramona Haji-Seyed-Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W. Shahab, Haritha Kunhiraman, James Ross, Gabrielle A. Price, Abhinav Dey, Dolores Hambardzumyan, Tobey MacDonald, David S. Yu, Christopher C. Porter, Anna M. Kenney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Y-box binding protein 1 (YBX1 or YB1) is a therapeutically relevant oncoprotein capable of RNA and DNA binding and mediating protein–protein interactions that drive proliferation, stemness, and resistance to platinum-based therapies. Given
Externí odkaz:
https://doaj.org/article/425775788bf245a2acd870d8014152f4
Autor:
Haritha Kunhiraman, Leon McSwain, Shubin W. Shahab, Timothy R. Gershon, Tobey J. MacDonald, Anna Marie Kenney
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Medulloblastoma (MB) is the most common pediatric brain malignancy and is divided into four molecularly distinct subgroups: WNT, Sonic Hedgehog (SHHp53mut and SHHp53wt), Group 3, and Group 4. Previous reports suggest that SHH MB features a u
Externí odkaz:
https://doaj.org/article/0cd8c8f588934e6087c82e48042e31b0
Autor:
Leon F. McSwain, Claire E. Pillsbury, Ramona Haji‑Seyed‑Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W. Shahab, Haritha Kunhiraman, James Ross, Gabrielle A. Price, Abhinav Dey, Dolores Hambardzumyan, Tobey MacDonald, David S. Yu, Christopher C. Porter, Anna M. Kenney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/ff47403e1e7249699d95fc35ba65c551
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Cancer initiation, progression, and metastasis leverage many regulatory agents, such as signaling molecules, transcription factors, and regulatory RNA molecules. Among these, regulatory non-coding RNAs have emerged as molecules that control multiple
Externí odkaz:
https://doaj.org/article/32a6a48448664d24a8c412e4eb6d477b
Publikováno v:
Neuro-Oncology. 24:vii289-vii289
Medulloblastoma (MB) is the most common pediatric brain malignancy. MB comprises 5 major subgroups known as WNT, SHH p53wt, SHH p53mut, Group 3 and Group 4. Among the four MB subgroups SHH group is the most dominant molecular subgroup in infants and
CSIG-34. LIN28B-LET-7-PBK PATHWAY IS AN IMPORTANT REGULATOR OF GROUP 3 MEDULLOBLASTOMA PROLIFERATION
Autor:
Shubin Shahab, Jessica Sun, Haritha Kunhiraman, Matthew Schneiderjan, Kyle Juraschka, Sachin Kumar, Michael Taylor, Tobey MacDonald, Anna Kenney
Publikováno v:
Neuro-Oncology. 24:vii46-vii46
Children with Group 3 medulloblastoma (MB) have a very poor long-term outcome and many do not survive beyond 5 years. Several drivers for Group 3 MB have been identified but none have resulted in targeted therapy to date. LIN28B is a stem cell factor
Autor:
Stacie Stapleton, Robert J. Wechsler-Reya, Alexandra Garancher, Bongyong Lee, Ranjan J Perera, Chetan Bettegowda, Haritha Kunhiraman, Keisuke Katsushima, Hector Monforte, Rajeev Vibhakar, Jun Yin, Rabi Murad, Cuncong Zhong, Eric H. Raabe, Ben Liu, Ignacio Gonzalez-Gomez, Charles G. Eberhart, George I. Jallo
Publikováno v:
Neuro Oncol
Background Medulloblastoma (MB) is an aggressive brain tumor that predominantly affects children. Recent high-throughput sequencing studies suggest that the noncoding RNA genome, in particular long noncoding RNAs (lncRNAs), contributes to MB subgroup
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Frontiers in Oncology
Frontiers in Oncology
Cancer initiation, progression, and metastasis leverage many regulatory agents, such as signaling molecules, transcription factors, and regulatory RNA molecules. Among these, regulatory non-coding RNAs have emerged as molecules that control multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313b39531eaf73afed43a8fb9026bf5c
https://resolver.caltech.edu/CaltechAUTHORS:20210302-125647289
https://resolver.caltech.edu/CaltechAUTHORS:20210302-125647289