Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hariom Singh"'
Autor:
HariOm Singh, Shyamveer, Chandrashekhar Jori, Supriya D. Mahajan, Ravikumar Aalinkeel, Kathiravan Kaliyappan, Meenakshi Bhattacharya, Mohammad Khalid Parvez, Mohammed S. Al-Dosari
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30519- (2024)
Apolipoproteins and Scavenger Receptor Class B1 (SCARB1) proteins are involved in the etiology of HIV-associated lipodystrophy (HIVLD). APOC3 3238C/G, APOB 12669G/A and SCARB1 1050C/T polymorphisms were linked with increased level of APOB, TG, HDL-C
Externí odkaz:
https://doaj.org/article/a87cc60e3198455cad820736d90b407b
Autor:
HariOm Singh, Kishore Dhotre, Shyamveer, Ranjana Choudhari, Amita Verma, Supriya D. Mahajan, Nemat Ali
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Background The ABCG2 421C/A polymorphism contributes significantly to the distribution and absorption of antiretroviral (ARV) regimens and is associated with the undesirable side effects of efavirenz. Methods To investigate this, we examined
Externí odkaz:
https://doaj.org/article/70ecb5e9d66442d2bf485c163a678ed9
Autor:
HariOm Singh, Chandrashekhar Jori, Shyamveer, Supriya D. Mahajan, Ravikumar Aalinkeel, Kathiravan Kaliyappan, Stanley A. Schwartz, Meenakshi Bhattacharya, Ruhi Shaikh, Madhukar Salve, Jyoti Deshmukh, Nemat Ali, Mohammad Khalid Parvez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
HIV-associated lipodystrophy (HIVLD) is a metabolic condition with an irregularity in the production of lipoprotein particles, and its occurrence varies among HIV-infected patients. MTP and ABCG2 genes have a role in the transport of lipoproteins. Th
Externí odkaz:
https://doaj.org/article/667afad5a9384b1e88ad2e20bef2fcfc
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Most polyphenols can cross blood-brain barrier, therefore, they are widely utilized in the treatment of various neurodegenerative diseases (ND). Resveratrol, a natural polyphenol contained in blueberry, grapes, mulberry, etc., is well documented to e
Externí odkaz:
https://doaj.org/article/0e8def08b958494e960ae59773b58b17
Autor:
Prateek Pathak, Vikas Kumar, Habibullah Khalilullah, Maria Grishina, HariOm Singh, Amita Verma
Publikováno v:
Molecules, Vol 27, Iss 14, p 4499 (2022)
The current study was conducted to exemplify the effect of debelalactone on tissue protection, chronic hepatic inflammation, hepatic protection and oxidative stress induced by diethyl nitrosamine in Wistar rats. Therefore, DEN (200 mg/kg) was used fo
Externí odkaz:
https://doaj.org/article/2d169d31e2904e0d84567134da9cd3c4
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract Background Plasma concentrations of antiretrovirals (ARVs) regimens have considerably varied in individuals of human immunodeficiency virus (HIV) because of variations in the expression of drug‐metabolizing and transporter genes. Transport
Externí odkaz:
https://doaj.org/article/a05618dd8ac847baa8e0c7a1cc065e1f
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Toll-like receptors (TLRs) play an important role in the innate immune response to HIV infection. Single nucleotide polymorphism (SNP) in TLR7 (Gln11Leu) gene has been associated with a rapid decline of CD4T cell count. Hence, we assessed the TLR7 (r
Externí odkaz:
https://doaj.org/article/70aa1842414649f1a9507121ee981cc4
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
The imbalance between MMPs and TIMPs is associated with the HIV dissemination tissue damage pathology neurodegenerative disorders, including HAND. Genetic variations in the TIMP gene may modulate the neurocognitive disorder in HIV patients. Hence, we
Externí odkaz:
https://doaj.org/article/da0ed285283345b09dd2009d291d0fd0
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
The severity of hepatic injury depends upon cytokines. Previous studies associated IL-1RN allele 2 with IL-1β production. Hence, we examined the association of IL-1 RN and IL-1β polymorphisms with ARV-associated hepatotoxicity. Genotyping of IL-1RN
Externí odkaz:
https://doaj.org/article/db54eeb814204eb9b387beb9644ddd49
Autor:
HariOm Singh, Dharmesh Samani
Publikováno v:
Current HIV Research. 20:397-406
Background: TLR3 polymorphisms affect the risk of HIV infection and modify the disease course. Consequently, we analyzed the association of TLR3 polymorphism (rs5743312, rs3775296, and rs3775291) with susceptibility to HIV-1 acquisition and disease p