Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Harini P. Kothari"'
Autor:
Kim R. Simpfendorfer, Wentian Li, Andrew Shih, Hongxiu Wen, Harini P. Kothari, Edward A. Einsidler, Arthur Wuster, Julie Hunkapiller, Timothy W. Behrens, Robert R. Graham, Michael J. Townsend, Doron M. Behar, Rui Hu, Elliott Greenspan, Peter K. Gregersen
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 19, Iss , Pp - (2019)
Objectives: The gene encoding glucose transporter 3 (GLUT3, SLC2A3) is present in the human population at variable copy number. An overt disease phenotype of SLC2A3 copy number variants has not been reported; however, deletion of SLC2A3 has been prev
Externí odkaz:
https://doaj.org/article/3acbee21fb1b430b93d5f749508543c9
Autor:
Andrew Shih, Robert R. Graham, Elliott Greenspan, Edward A. Einsidler, Wentian Li, Doron M. Behar, Harini P. Kothari, Timothy W. Behrens, Michael J. Townsend, Peter K. Gregersen, Kim R. Simpfendorfer, Rui Hu, Arthur Wuster, Hongxiu Wen, Julie Hunkapiller
Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 19, Iss, Pp-(2019)
Molecular Genetics and Metabolism Reports, Vol 19, Iss, Pp-(2019)
Objectives The gene encoding glucose transporter 3 (GLUT3, SLC2A3) is present in the human population at variable copy number. An overt disease phenotype of SLC2A3 copy number variants has not been reported; however, deletion of SLC2A3 has been previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b503c617bbeffa65fab82acda785b478
http://europepmc.org/articles/PMC6453668
http://europepmc.org/articles/PMC6453668
Publikováno v:
Journal of Neuro-Oncology. 117:225-234
Glioblastoma is the most common, and at the same time, most aggressive type of high-grade glioma (HGG). The prognosis of glioblastoma patients treated with standard therapy including surgery, temozolomide and radiation therapy remains poor. Peroxisom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417a7faf0776be0e686e6e39c2bc7c68
https://doi.org/10.1007/s11060-014-1385-6
https://doi.org/10.1007/s11060-014-1385-6
Publikováno v:
Journal of Cancer
Evidence has pointed to brain tumor stem cells (BTSC) as culprits behind human high-grade glioma (hHGG) resistance to standard therapy. Pre-clinical rodent models are the mainstay for testing of new therapeutic strategies. The typical model involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db51c12e548aec5eea806bdb82e52477
http://europepmc.org/articles/PMC3328782
http://europepmc.org/articles/PMC3328782
Publikováno v:
Stem Cells and Development. 21:404-410
Human high-grade gliomas (hHGG) remain a therapeutic challenge in neuro-oncology despite current multimodality treatments. We recently demonstrated that murine embryonic stem cell (mESC)-derived astrocytes conditionally expressing proapoptotic genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76671ba5949621096e9cf11136024dc1
https://doi.org/10.1089/scd.2010.0560
https://doi.org/10.1089/scd.2010.0560
Publikováno v:
Journal of Cancer, Vol 3, Iss 1, Pp 166-174 (2012)
Evidence has pointed to brain tumor stem cells (BTSC) as culprits behind human high-grade glioma (hHGG) resistance to standard therapy. Pre-clinical rodent models are the mainstay for testing of new therapeutic strategies. The typical model involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::456b3cb9b6ca8b53c4012e46a0d90ecd
http://www.jcancer.org/v03p0166.htm
http://www.jcancer.org/v03p0166.htm
Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas?
Autor:
Zulekha A. Qadeer, Luni Emdad, Harini P. Kothari, Lucia B. Bederson, Isabelle M. Germano, Mahmud Uzzaman
Publikováno v:
Neuro-Oncology. 13:725-735
The prognosis of patients with human high-grade gliomas (HGGs) remains dismal despite major advances in their management, due mainly to the high resistance of these infiltrative tumor cells to programmed cell death (PCD). Most therapeutic strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656418117c876c4628d22aa2aeb26407
https://doi.org/10.1093/neuonc/nor053
https://doi.org/10.1093/neuonc/nor053