Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Harini Chakravarthy"'
Autor:
Brian Hsueh, Vanessa M. Burns, Philip Pauerstein, Katherine Holzem, Li Ye, Kristin Engberg, Ai-Chi Wang, Xueying Gu, Harini Chakravarthy, H. Efsun Arda, Gregory Charville, Hannes Vogel, Igor R. Efimov, Seung Kim, Karl Deisseroth
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods
Externí odkaz:
https://doaj.org/article/b005b26d2af84e9196f1657c71463209
Autor:
K. Liu, Harini Chakravarthy, Patrick E. MacDonald, Fabrizio Thorel, Martin Enge, Xueying Gu, Stephen R. Quake, Jose Oberholzer, Xiao-Qing Dai, Jing Wang, Carolina Downie, Seung K. Kim, Nicolas Damond, Yuan Xing, Simona Chera, Yong Wang, Pedro Luis Herrera
Publikováno v:
Cell Metabolism, Vol. 25, No 3 (2017) pp. 622-634
Insulin-producing pancreatic β cells in mice can slowly regenerate from glucagon-producing α cells in settings like β cell loss, but the basis of this conversion is unknown. Moreover, it remains unclear if this intra-islet cell conversion is relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a7fc0a5966f1f8cc5554dc781cce5b
https://pubmed.ncbi.nlm.nih.gov/28273469
https://pubmed.ncbi.nlm.nih.gov/28273469
Publikováno v:
The FASEB Journal. 25:206-218
The rapid formation of numerous tissues during development is highly dependent on the swift activation of key developmental regulators. Recent studies indicate that many key regulatory genes are repressed in embryonic stem cells (ESCs), yet poised fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227d5c4575aaf86a5336362ec5f2f84b
https://doi.org/10.1096/fj.10-166926
https://doi.org/10.1096/fj.10-166926
Autor:
Michelle Desler, Sunil K. Mallanna, Harini Chakravarthy, Angie Rizzino, Brian Boer, Timothy W. McKeithan
Publikováno v:
Journal of Cellular Physiology. 216:651-662
Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis, where they are believed to regulate a critical gene regulatory network by cooperatively binding to DNA regulatory regions composed of adjacent HMG and POU motifs (HMG/POU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d26c9a13f32a350cc5d0e7af6444a9e
https://doi.org/10.1002/jcp.21440
https://doi.org/10.1002/jcp.21440
Autor:
Heshan Peiris, Elizabeth Conrad, Harini Chakravarthy, Xueying Gu, Emily M. Walker, Roland Stein, Ronadip R. Banerjee, Holly A. Cyphert, Seung K. Kim, Lisa V. Goodrich, Yinghua Liu
Publikováno v:
Diabetes
β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor (PRLR) and contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949c5cca4139f36eefe417df30395dc9
https://pubmed.ncbi.nlm.nih.gov/27217483
https://pubmed.ncbi.nlm.nih.gov/27217483
Publikováno v:
Biochemical and biophysical research communications. 381(4)
There is a pressing need for new therapies to treat pancreatic cancer. In principle, this could be achieved by taking advantage of signaling pathways that are active in tumor, but not normal, cells. The work described in this study set out to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfb42322669d51e24221387328c4e01
https://pubmed.ncbi.nlm.nih.gov/19254697
https://pubmed.ncbi.nlm.nih.gov/19254697
Autor:
Angie Rizzino, Sunil K. Mallanna, Harini Chakravarthy, Cory T. Bernadt, Michelle Desler, Janel L. Kopp, Phillip J. Wilder, Brian Boer
Publikováno v:
Nucleic Acids Research
Recent studies have identified large sets of genes in embryonic stem and embryonal carcinoma cells that are associated with the transcription factors Sox2 and Oct-3/4. Other studies have shown that Sox2 and Oct-3/4 work together cooperatively to stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d25c9d23a7cf7c55a09f92b44ac0fdc
https://pubmed.ncbi.nlm.nih.gov/17324942
https://pubmed.ncbi.nlm.nih.gov/17324942