Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Harini Bagavant"'
Autor:
Kai-Ting Huang, Larry E Wagner, Takahiro Takano, Xiao-Xuan Lin, Harini Bagavant, Umesh Deshmukh, David I Yule
Publikováno v:
eLife, Vol 13 (2024)
The molecular mechanisms leading to saliva secretion are largely established, but factors that underlie secretory hypofunction, specifically related to the autoimmune disease Sjögren’s syndrome (SS) are not fully understood. A major conundrum is t
Externí odkaz:
https://doaj.org/article/e07abbfbd21f45a2aa0390bf625a9080
Autor:
Harini Bagavant, Katarzyna Cizio, Antonina M. Araszkiewicz, Joanna A. Papinska, Lori Garman, Chuang Li, Nathan Pezant, Wonder P. Drake, Courtney G. Montgomery, Umesh S. Deshmukh
Publikováno v:
Journal of Translational Autoimmunity, Vol 5, Iss , Pp 100153- (2022)
A characteristic feature of sarcoidosis is a dysregulated immune response to persistent stimuli, often leading to the formation of non-necrotizing granulomas in various organs. Although genetic susceptibility is an essential factor in disease develop
Externí odkaz:
https://doaj.org/article/788fd771b34b45c69b448d95da2ef1f0
Autor:
Marta E Alarcón-Riquelme, Guillermo Barturen, Nieves Varela, Harini Bagavant, Maria Morell, Gonzalo Gómez-Hernández
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/8eea4426053a4d0d811b57bb3cbb425c
Autor:
Harini Bagavant, Antonina M. Araszkiewicz, Jessica K. Ingram, Katarzyna Cizio, Joan T. Merrill, Cristina Arriens, Joel M. Guthridge, Judith A. James, Umesh S. Deshmukh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interactions between gut microbes and the immune system influence autoimmune disorders like systemic lupus erythematosus (SLE). Recently, Enterococcus gallinarum, a gram-positive commensal gut bacterium, was implicated as a candidate pathobiont in SL
Externí odkaz:
https://doaj.org/article/4d5b5947541e4e289da4ffb75685e5e4
Autor:
Lori Garman, Richard C. Pelikan, Astrid Rasmussen, Caleb A. Lareau, Kathryn A. Savoy, Umesh S. Deshmukh, Harini Bagavant, Albert M. Levin, Salim Daouk, Wonder P. Drake, Courtney G. Montgomery
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sarcoidosis is a systemic inflammatory disease characterized by infiltration of immune cells into granulomas. Previous gene expression studies using heterogeneous cell mixtures lack insight into cell-type-specific immune dysregulation. We performed t
Externí odkaz:
https://doaj.org/article/915f931d44ef4657bccd2db36474b55b
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156302 (2016)
The purpose of our study was to investigate the effects of the adaptor Bank1 in TLR7 signaling using the B6.Sle1.yaa mouse, a lupus model that develops disease through exacerbated TLR7 expression. Crosses of B6.Sle1.yaa with Bank1-/- mice maintained
Externí odkaz:
https://doaj.org/article/3eae60fb91f04d079b5d516822e18bd0
Autor:
Harini Bagavant, Marta Trzeciak, Indranil Biswas, Joanna A. Papinska, Katarzyna Cizio, Umesh S. Deshmukh
Publikováno v:
Journal of Oral Pathology & Medicine. 51:674-677
Oral and ocular dryness due to reduced saliva and tear production, exocrine gland inflammation, and autoantibodies to multiple cellular proteins are the cardinal features of Sjögren's Disease. Among the autoantibody specificities, anti-Ro52 is linke
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 4128
Volume 24
Issue 4
Pages: 4128
Activation of the Stimulator of Interferon Genes (STING) protein has paradoxical outcomes in skin disease. STING activation exacerbates psoriatic skin disease and delays wound healing in diabetic mice, yet it also facilitates wound healing in normal
Autor:
Harini Bagavant, Antonina M. Araszkiewicz, Astrid Rasmussen, Nathan Pezant, Courtney Montgomery, Robert Hal Scofield, Darise Farris, Christopher J. Lessard, Umesh S. Deshmukh
Publikováno v:
Clinical Immunology. 247:109243
Autor:
Maria Morell, Guillermo Barturen, Nieves Varela, Marta E. Alarcón-Riquelme, Harini Bagavant, Gonzalo Gómez-Hernández
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)