Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Harim I. Won"'
Autor:
Harim I. Won, Samuel Zinga, Olga Kandror, Tatos Akopian, Ian D. Wolf, Jessica T. P. Schweber, Ernst W. Schmid, Michael C. Chao, Maya Waldor, Eric J. Rubin, Junhao Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Proteolysis-targeting chimeras (PROTACs) represent a new therapeutic modality involving selectively directing disease-causing proteins for degradation through proteolytic systems. Our ability to exploit targeted protein degradation (TPD) for
Externí odkaz:
https://doaj.org/article/b9ac70b36b4b4800bd5cfffe2f4e65d9
Autor:
Harim I. Won, Junhao Zhu, Olga Kandror, Tatos Akopian, Ian D. Wolf, Michael C. Chao, Maya Waldor, Eric J. Rubin
Proteolysis-targeting chimeras (PROTACs) represent a new therapeutic modality involving selectively directing disease-causing proteins for degradation through proteolytic systems. Our ability to exploit this targeted protein degradation (TPD) approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f587f1cea4bfa5f269a83d7d337acd
https://doi.org/10.1101/2023.02.14.528552
https://doi.org/10.1101/2023.02.14.528552
Autor:
Jong Sam Ahn, Marat R. Sadykov, Jennifer L. Endres, Kenneth W. Bayles, Harim I. Won, Sean M. Watson
Publikováno v:
Journal of Bacteriology. 203
Under conditions of glucose excess, aerobically growing bacteria predominantly direct carbon flux toward acetate fermentation, a phenomenon known as overflow metabolism or the bacterial “Crabtree effect.” Numerous studies of the major acetate-gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24b376c98898a47f4cd21bdcefd59702
https://doi.org/10.1128/jb.00660-20
https://doi.org/10.1128/jb.00660-20
Autor:
Thomas T. Schulze, Abigail K. Judge, Harim I. Won, Andrew J. Neville, Paul H. Davis, Matthew C Martens, Madalyn M Won, Jonathan L. Vennerstrom
Publikováno v:
Antimicrob Agents Chemother
Toxoplasma gondii is a globally distributed apicomplexan parasite and the causative agent of toxoplasmosis in humans. While pharmaceuticals exist to combat acute infection, they can produce serious adverse reactions, demonstrating a need for enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4f5642dddbca857e8f61d28f8f0703
https://europepmc.org/articles/PMC8092512/
https://europepmc.org/articles/PMC8092512/
Autor:
Harim I, Won, Sean M, Watson, Jong-Sam, Ahn, Jennifer L, Endres, Kenneth W, Bayles, Marat R, Sadykov
Publikováno v:
J Bacteriol
Under conditions of glucose excess, aerobically growing bacteria predominantly direct carbon flux toward acetate fermentation, a phenomenon known as overflow metabolism or the bacterial “Crabtree effect.” Numerous studies of the major acetate-gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58ea901a17680b0ec0e8de851e3692d0
https://pubmed.ncbi.nlm.nih.gov/33593944
https://pubmed.ncbi.nlm.nih.gov/33593944
Autor:
Mark A Schoenbeck, Thomas T. Schulze, Elizabeth A M Ramler, Harim I. Won, Elias J Witte, Emalie J. Clement, Paul H. Davis, Rosalie C. Warner, Sean M Watson, Claudia M. Rauter, Gabrielle F. Watson
Publikováno v:
Journal of Genomics
Burying beetles (Nicrophorus spp.) are among the relatively few insects that provide parental care while not belonging to the eusocial insects such as ants or bees. This behavior incurs energy costs as evidenced by immune deficits and shorter life-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eefe093f6e1d963284d50f44e6d6623
http://europepmc.org/articles/PMC5916875
http://europepmc.org/articles/PMC5916875