Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Harikrishnareddy Paluvai"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Histone deacetylase 3 (HDAC3) and nuclear receptor co-repressor (NCoR1/2) are epigenetic regulators that play a key role in gene expression and metabolism. HDAC3 is a class I histone deacetylase that functions as a transcriptional co-repressor, modul
Externí odkaz:
https://doaj.org/article/326bb1f37528494c8700580aed27bfaf
Autor:
Eros Di Giorgio, Harikrishnareddy Paluvai, Emiliano Dalla, Liliana Ranzino, Alessandra Renzini, Viviana Moresi, Martina Minisini, Raffaella Picco, Claudio Brancolini
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Cellular senescence is a permanent state of replicative arrest defined by a specific pattern of gene expression. The epigenome in senescent cells is sculptured in order to sustain the new transcriptional requirements, particularly
Externí odkaz:
https://doaj.org/article/e1bf26ea795149a1901c71d8ba176257
Publikováno v:
Molecular Oncology, Vol 12, Iss 12, Pp 2165-2181 (2018)
Expression of the class IIa HDACs is frequently altered in different human cancers. In mouse models these transcriptional repressors can trigger transformation, acting as bona fide oncogenes. Whether class IIa HDACs also exhibit transforming activiti
Externí odkaz:
https://doaj.org/article/280acd433acc4f62975215798b76e67c
Publikováno v:
Cells, Vol 9, Iss 2, p 466 (2020)
Senescence is the end point of a complex cellular response that proceeds through a set of highly regulated steps. Initially, the permanent cell-cycle arrest that characterizes senescence is a pro-survival response to irreparable DNA damage. The maint
Externí odkaz:
https://doaj.org/article/d28251d3c1e547d5814cd9a89c7f9d44
Autor:
Eros Di Giorgio, Elisa Franforte, Sebastiano Cefalù, Sabrina Rossi, Angelo Paolo Dei Tos, Monica Brenca, Maurizio Polano, Roberta Maestro, Harikrishnareddy Paluvai, Raffaella Picco, Claudio Brancolini
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006752 (2017)
The contribution of MEF2 TFs to the tumorigenic process is still mysterious. Here we clarify that MEF2 can support both pro-oncogenic or tumor suppressive activities depending on the interaction with co-activators or co-repressors partners. Through t
Externí odkaz:
https://doaj.org/article/ce22d3566e6d46abb5ecbdbb647d5627
Autor:
Viviana Moresi, Emiliano Dalla, Liliana Ranzino, Claudio Brancolini, Eros Di Giorgio, Raffaella Picco, Martina Minisini, Harikrishnareddy Paluvai, Alessandra Renzini
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Genome Biology
Genome Biology
Background Cellular senescence is a permanent state of replicative arrest defined by a specific pattern of gene expression. The epigenome in senescent cells is sculptured in order to sustain the new transcriptional requirements, particularly at enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5924870c31abe1d27fef694fad3ef9e5
https://doaj.org/article/e1bf26ea795149a1901c71d8ba176257
https://doaj.org/article/e1bf26ea795149a1901c71d8ba176257
Autor:
Di Giorgio, Eros, Harikrishnareddy Paluvai, Dalla, Emiliano, Ranzino, Liliana, Renzini, Alessandra, Moresi, Viviana, Minisini, Martina, Picco, Raffaella, Brancolini, Claudio
Additional file 1: Supplementary figures/All supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172b8adbdad5558600c887875bfda8cc
Autor:
Di Giorgio, Eros, Harikrishnareddy Paluvai, Dalla, Emiliano, Ranzino, Liliana, Renzini, Alessandra, Moresi, Viviana, Minisini, Martina, Picco, Raffaella, Brancolini, Claudio
Additional file 9. Review history.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4b5710a37bc428317fcaad28891c3c
Autor:
Viviana Moresi, Claudio Brancolini, Valentina Cutano, Harikrishnareddy Paluvai, Raffaella Picco, Emiliano Dalla, Alessandra Renzini, Eros Di Giorgio, Liliana Ranzino
The epigenome of senescent cells is characterized by a deep redistribution of H3K27 acetylation. H3K27 is target of class IIa Histone Deacetylases (HDAC4, 5, 7, 9) as part of large repressive complexes. We report here that, among class IIa HDACs, HDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35aed5c8eb969f3e041861d03c78ddb
https://doi.org/10.1101/2020.06.04.132787
https://doi.org/10.1101/2020.06.04.132787
Autor:
Emiliano Dalla, Claudio Brancolini, Raffaella Picco, Martina Minisini, Elisa Franforte, Harikrishnareddy Paluvai, Matteo Trevisanut, Eros Di Giorgio
Publikováno v:
Nucleic Acids Research
Transcriptional networks supervising class IIa HDAC expression are poorly defined. Here we demonstrate that MEF2D is the key factor controlling HDAC9 transcription. This control, which is part of a negative feed-back loop during muscle differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209ee0fa1dcb65f5f78611f87bec0fd7
http://hdl.handle.net/11390/1177480
http://hdl.handle.net/11390/1177480