Výsledky vyhledávání - "Harika Meduru"

Dissertation/ Thesis

Dipeptidyl Peptidase-4 (DPP-4) Enzyme Inhibitor Study by In Silico Analysis: Molecular Docking, Pharmacophore Generation and Molecular Dynamics Simulation in Treatment of Type-2 Diabetes

Autor: Harika Meduru

104
Dipeptidyl peptidase-4 (DPP-4) is the vital enzyme responsible for inactivating intestinal peptides Glucagon like peptide-1 (GLP-1) and Gastric inhibitory polypeptide (GIP), which stimulates a decrease in blood glucose levels. The aim of thi

Externí odkaz: http://ndltd.ncl.edu.tw/handle/55336938559078403490

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Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation

Autor: Yu-Ching Chen, Jeffrey J. P. Tsai, Harika Meduru, Yeng-Tseng Wang

Publikováno v: International Journal of Molecular Sciences; Volume 17; Issue 6; Pages: 920
International Journal of Molecular Sciences, Vol 17, Iss 6, p 920 (2016)
International Journal of Molecular Sciences

Dipeptidyl peptidase-4 (DPP-4) is the vital enzyme that is responsible for inactivating intestinal peptides glucagon like peptide-1 (GLP-1) and Gastric inhibitory polypeptide (GIP), which stimulates a decline in blood glucose levels. The aim of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5825bcf8a56187d8c4fb93d7a8449876
https://doi.org/10.3390/ijms17060920

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In-silico identification of potential antagonists for human Casein kinase II subunit alpha' (CK2α2)

Autor: Navya Pallapotu, Harika Meduru, Kanipakam Hema, Amineni Umamaheswari

Publikováno v: Nature Precedings.

Human CK2α2 is an enzyme that belongs to the Serine/Threonine protein kinase family which is involved in signal transduction. Over expression of CK2α2 causes kidney cancer therefore, human CK2α2 has been identified as a drug target for the develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77c33d1202ea419821e5af7c8104d1da
https://doi.org/10.1038/npre.2012.6958.1

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Lead identification and docking studies of metastatic protein human mitogen activated protein kinase kinase4

Autor: Harika Meduru, Dibyabhaba Pradhan, Manne Munikumar, Amineni Umamaheswari

Publikováno v: Nature Precedings.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a94e5d6afc22d1d33c630f3bffc41ac
https://doi.org/10.1038/npre.2010.5457

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