Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Hariharan Easwaran"'
Autor:
Lijing Yang, Lei Tu, Shilpa Bisht, Yiqing Mao, Daniel Petkovich, Sara-Jayne Thursby, Jinxiao Liang, Nibedita Patel, Ray-Whay Chiu Yen, Tina Largent, Cynthia Zahnow, Malcolm Brock, Kathy Gabrielson, Kevan J. Salimian, Stephen B. Baylin, Hariharan Easwaran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Cancers of the same tissue-type but in anatomically distinct locations exhibit different molecular dependencies for tumorigenesis. Proximal and distal colon cancers exemplify such characteristics, with BRAF V600E predominantly occurring in p
Externí odkaz:
https://doaj.org/article/3f013a66468a4721a00011bbfc649fca
Autor:
Jonathan B Coulter, Hariharan Easwaran
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002081 (2023)
Development of resistance in castration-resistant prostate cancer (CRPC) involves epigenetic pathways. A new study in PLOS Biology demonstrates that combined therapy targeting enhancer of zeste homolog 2 (EZH2) and histone deacetylases (HDACs) may se
Externí odkaz:
https://doaj.org/article/613dcf62225e4a31a73fa8a911c2ab2c
Autor:
Rossin Erbe, Zheyu Wang, Sharon Wu, Joanne Xiu, Neeha Zaidi, Jennifer La, David Tuck, Nathanael Fillmore, Nicolas A. Giraldo, Michael Topper, Stephen Baylin, Marc Lippman, Claudine Isaacs, Reva Basho, Ilya Serebriiskii, Heinz-Josef Lenz, Igor Astsaturov, John Marshall, Josephine Taverna, Jerry Lee, Elizabeth M. Jaffee, Evanthia T. Roussos Torres, Ashani Weeraratna, Hariharan Easwaran, Elana J. Fertig
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110033- (2021)
Externí odkaz:
https://doaj.org/article/1929927bbd9e4b6ca3ee96700e38831f
Autor:
Hariharan Easwaran, Lijing Yang, Lei Tu, Daniel Petkovich, Sara-Jayne Thursby, Shilpa Bisht, Yiqing Mao, Kathy Gabrielson, Ray-Whay Chiu Yen, Tina Largent, Malcolm Brock, Cynthia Zahnow, Stephen Baylin
It is unknown why cancers of the same tissue-type but in anatomically distinct locations exhibit different molecular dependencies for tumorigenesis. Proximal and distal colon cancers (CC) exemplify such characteristics, with BRAFV600E predominantly o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1f3c4b8d7708562c77ed6e276e0f09
https://doi.org/10.21203/rs.3.rs-2846349/v1
https://doi.org/10.21203/rs.3.rs-2846349/v1
Autor:
Stephen B. Baylin, Hariharan Easwaran, Marie Classon, Patrick Trojer, David Arnott, Tommy K. Cheung, Catherine Wilson, Ioannis Kagiampakis, Benjamin R. Leadem
Contains Tables S1 and S2. Supplementary Table 1: List of PCR primers. Supplementary Table 2: Sensitivity of Breast Cancer Cell Lines to CPI-455 Cell Viability was measured following exposure to CPI-455 for 8 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4e7fae45bdbac8c44974efd5328bfc
https://doi.org/10.1158/0008-5472.22411056
https://doi.org/10.1158/0008-5472.22411056
Autor:
Malcolm V. Brock, James G. Herman, Stephen B. Baylin, Steven A. Belinsky, Jun Amano, Nita Ahuja, Craig M. Hooker, Julien Licchesi, Kornel E. Schuebel, Hariharan Easwaran, Leander Van Neste, Mathewos Tessema, Sabine C. Glöckner, Wei Zhang, Noreli Franco, Alicia Hulbert, Ludmila Danilova, Emi Ota Machida, John Wrangle
PDF file - 2177KB, Scatter Plots of Gene Re-expression with Decitabine or Trichostatin-A in Eight Non-Small Cell Lung Cancer Cell Lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccfc984e81571c0ad8eed3d1d27c555
https://doi.org/10.1158/1078-0432.22451390
https://doi.org/10.1158/1078-0432.22451390
Autor:
Malcolm V. Brock, James G. Herman, Stephen B. Baylin, Steven A. Belinsky, Jun Amano, Nita Ahuja, Craig M. Hooker, Julien Licchesi, Kornel E. Schuebel, Hariharan Easwaran, Leander Van Neste, Mathewos Tessema, Sabine C. Glöckner, Wei Zhang, Noreli Franco, Alicia Hulbert, Ludmila Danilova, Emi Ota Machida, John Wrangle
PDF file - 287KB, DNA Methylation of CDO1, HOXA9, and TAC1 is Highly Sensitive for Stage I NSCLC in the Cancer Genome Atlas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087b692cd90278ab54bfaa80e695ef42
https://doi.org/10.1158/1078-0432.22451384.v1
https://doi.org/10.1158/1078-0432.22451384.v1
Autor:
Stephen B. Baylin, Hariharan Easwaran, Marie Classon, Patrick Trojer, David Arnott, Tommy K. Cheung, Catherine Wilson, Ioannis Kagiampakis, Benjamin R. Leadem
Effects of KDM5i and DAC on enhancers and de novo super-enhancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080240ddfe7230e203c294e19dd14b77
https://doi.org/10.1158/0008-5472.22411068.v1
https://doi.org/10.1158/0008-5472.22411068.v1
Autor:
Malcolm V. Brock, James G. Herman, Stephen B. Baylin, Steven A. Belinsky, Jun Amano, Nita Ahuja, Craig M. Hooker, Julien Licchesi, Kornel E. Schuebel, Hariharan Easwaran, Leander Van Neste, Mathewos Tessema, Sabine C. Glöckner, Wei Zhang, Noreli Franco, Alicia Hulbert, Ludmila Danilova, Emi Ota Machida, John Wrangle
PDF file - 399KB, Kaplan-Meier Survival Curves for Non-Small Cell Lung Cancer for p16 methylation in combination with APC, RASSF1, or CDH13.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e69cc4695f6f5b41416b63b00cf10f
https://doi.org/10.1158/1078-0432.22451381.v1
https://doi.org/10.1158/1078-0432.22451381.v1
Autor:
Malcolm V. Brock, James G. Herman, Stephen B. Baylin, Steven A. Belinsky, Jun Amano, Nita Ahuja, Craig M. Hooker, Julien Licchesi, Kornel E. Schuebel, Hariharan Easwaran, Leander Van Neste, Mathewos Tessema, Sabine C. Glöckner, Wei Zhang, Noreli Franco, Alicia Hulbert, Ludmila Danilova, Emi Ota Machida, John Wrangle
Purpose: Non–small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the world. Novel diagnostic biomarkers may augment both existing NSCLC screening methods as well as molecular diagnostic tests of surgical specimens to more acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a649c8c8b922ba3187498dfda79e155
https://doi.org/10.1158/1078-0432.c.6522182.v1
https://doi.org/10.1158/1078-0432.c.6522182.v1