Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness.

Autor: Oropeza E; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Seker S; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Carrel S; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Mazumder A; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Lozano D; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Jimenez A; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., VandenHeuvel SN; Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA., Noltensmeyer DA; Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA., Punturi NB; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Lei JT; Lester and Sue Smith Breast Cancer Center, Baylor College of Medicine, Houston, TX, USA., Lim B; Lester and Sue Smith Breast Cancer Center, Baylor College of Medicine, Houston, TX, USA.; Department of Oncology/Medicine, Baylor College of Medicine, Houston, TX, USA., Waltz SE; Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA.; Research Service, Cincinnati Veteran's Affairs Medical Center, 3200 Vine St., Cincinnati, OH, USA., Raghavan SA; Texas A&M University, College Station, TX, USA., Bainbridge MN; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Haricharan S; Aging and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

Publikováno v: Science advances [Sci Adv] 2023 Jun 30; Vol. 9 (26), pp. eadf2860. Date of Electronic Publication: 2023 Jun 30.

ROLE OF ANTIOXIDANTS, FREE-RADICALS ON HUMAN HEALTH.

Autor: Patel, Haricharan S.¹

Publikováno v: International Journal of Pharmaceutical, Chemical & Biological Sciences. 2021, Vol. 11 Issue 3, p1-1. 1p.

Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome.

Autor: Bainbridge MN; Rady Children's Institute for Genomic Medicine (RCIGM), San Diego, CA 92123, USA., Mazumder A; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Ogasawara D; The Scripps Research Translational Institute, The Scripps Research Institute, La Jolla, CA 92037, USA., Abou Jamra R; Institute of Human Genetics, University Medical Center Leipzig, Leipzig 04103, Germany., Bernard G; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.; Department of Pediatrics and Human Genetics, McGill University, Montreal, Canada.; Department of Human Genetics, McGill University, Montreal, Canada.; Department Specialized Medicine, Division of Medical Genetics, McGill University Health Center, Montreal, Canada.; Child Health and Human Development Program, Research Institute of the McGill University Health Center, Montreal, Canada., Bertini E; Unit of Neuromuscular and Neurodegenerative Disorders, Department of Neurosciences 'Bambino Gesu' Children's Research Hospital, IRCCS, Rome, Italy., Burglen L; Centre de Référence Malformations et Maladies Congénitales du Cervelet, Département de génétique, AP-HP Sorbonne Université, Hôpital Trousseau, Paris, France.; Developmental Brain Disorders Laboratory, Imagine Institute, INSERM UMR 1163, Paris, France., Cope H; Department of Pediatrics, Division Medical Genetics Durham, Duke University Medical Center, North Carolina, USA., Crawford A; Illumina, San Diego, CA 92122, USA., Derksen A; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.; Child Health and Human Development Program, Research Institute of the McGill University Health Center, Montreal, Canada., Dure L; Division of Pediatric Neurology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Gantz E; Division of Pediatric Neurology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Koch-Hogrebe M; Vestische Kinder- und Jugendklinik, 45711 Datteln, Germany., Hurst ACE; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA., Mahida S; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA., Marshall P; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA., Micalizzi A; Translational Cytogenomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy., Novelli A; Translational Cytogenomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy., Peng H; The Scripps Research Translational Institute, The Scripps Research Institute, La Jolla, CA 92037, USA., Rodriguez D; Sorbonne Université, INSERM UMR 1141, AP-HP.SU, Centre de Référence Maladies Rares Malformations et Maladies Congénitales du Cervelet & Service de Neuropédiatrie, Hôpital Trousseau, Paris, France., Robbins SL; Ratner Children's Eye Center at the Shiley Eye Institute; Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, CA 92093, USA., Rutledge SL; Division of Pediatric Neurology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA., Scalise R; Department of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.; Tuscan PhD Program of Neuroscience, University of Florence, Pisa and Siena, Florence, Italy., Schließke S; Institute of Human Genetics, University Medical Center Leipzig, Leipzig 04103, Germany., Shashi V; Department of Pediatrics, Division Medical Genetics Durham, Duke University Medical Center, North Carolina, USA., Srivastava S; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA., Thiffault I; Genomic Medicine Center, Children's Mercy Hospital, Kansas City, Missouri, USA.; Faculty of Medicine, University of Missouri Kansas City, Kansas City, Missouri, USA.; Department of Pathology, Children's Mercy Hospital, Kansas City, Missouri, USA., Topol S; The Scripps Research Translational Institute, The Scripps Research Institute, La Jolla, CA 92037, USA., Qebibo L; Centre de Référence Malformations et Maladies Congénitales du Cervelet, Département de génétique, AP-HP Sorbonne Université, Hôpital Trousseau, Paris, France., Wieczorek D; Institute of Human Genetics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, 40225, Düsseldorf, Germany., Cravatt B; The Scripps Research Translational Institute, The Scripps Research Institute, La Jolla, CA 92037, USA., Haricharan S; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Torkamani A; The Scripps Research Translational Institute, The Scripps Research Institute, La Jolla, CA 92037, USA., Friedman J; Rady Children's Institute for Genomic Medicine (RCIGM), San Diego, CA 92123, USA.; Division of Neurology, Rady Children's Hospital San Diego, CA 92123, USA.; Department of Neurosciences, University of California La Jolla, CA 92037, USA.; Department of Pediatrics, University of California La Jolla, CA 92037, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2022 Oct 21; Vol. 145 (10), pp. 3383-3390.

Contribution of an alveolar cell of origin to the high-grade malignant phenotype of pregnancy-associated breast cancer.

Autor: Haricharan, S¹, Hein, S M¹, Dong, J¹, Toneff, M J¹, Aina, O H², Rao, P H³, Cardiff, R D², Li, Y¹

Publikováno v: Oncogene. 12/11/2014, Vol. 33 Issue 50, p5729-5739. 11p.

Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.

Autor: Garancher A; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Suzuki H; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada., Haricharan S; Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center and the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Chau LQ; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Masihi MB; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Rusert JM; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Norris PS; Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center and the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Carrette F; Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center and the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Romero MM; Department of Pediatrics, Northwestern University, Chicago, IL, USA., Morrissy SA; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada.; Dept. of Biochemistry and Molecular Biology, Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Skowron P; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada., Cavalli FMG; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada., Farooq H; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada., Ramaswamy V; Division of Haematology/Oncology and Department of Paediatrics, Hospital for Sick Children, Toronto, Canada., Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Mungall AJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Ma Y; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Thiessen N; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Li Y; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Morcavallo A; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom., Qi L; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Program of Precision Medicine PDOX Modeling of Pediatric Tumors, Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University, Chicago, IL, USA., Kogiso M; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Du Y; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Program of Precision Medicine PDOX Modeling of Pediatric Tumors, Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University, Chicago, IL, USA., Baxter P; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Henderson JJ; Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA., Crawford JR; Departments of Pediatrics and Neurosciences, University of California, San Diego - Rady Children's Hospital, San Diego, CA, USA., Levy ML; Department of Neurosurgery, University of California San Diego - Rady Children's Hospital, San Diego, CA, USA., Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Cho YJ; Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA., Deshpande AJ; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Li XN; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Program of Precision Medicine PDOX Modeling of Pediatric Tumors, Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University, Chicago, IL, USA., Chesler L; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom., Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada., Wajant H; Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany., Becher OJ; Department of Pediatrics, Northwestern University, Chicago, IL, USA., Bradley LM; Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center and the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Ware CF; Tumor Microenvironment and Cancer Immunology Program, NCI-Designated Cancer Center and the Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Taylor MD; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada., Wechsler-Reya RJ; Tumor Initiation & Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. rwreya@sbpdiscovery.org.

Publikováno v: Nature neuroscience [Nat Neurosci] 2022 Jan; Vol. 25 (1), pp. 127.