Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hari P. R. Mangunuru"'
Autor:
Eric Yu, Hari P. R. Mangunuru, Nakul S. Telang, Caleb J. Kong, Jenson Verghese, Stanley E. Gilliland III, Saeed Ahmad, Raymond N. Dominey, B. Frank Gupton
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 583-592 (2018)
Numerous synthetic methods for the continuous preparation of fine chemicals and active pharmaceutical ingredients (API’s) have been reported in recent years resulting in a dramatic improvement in process efficiencies. Herein we report a highly effi
Externí odkaz:
https://doaj.org/article/edaae01b8fa240dc90d1188373e91ee9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 3111-3121 (2014)
Small molecular gelators are a class of compounds with potential applications for soft biomaterials. Low molecular weight hydrogelators are especially useful for exploring biomedical applications. Previously, we found that 4,6-O-benzylidene acetal pr
Externí odkaz:
https://doaj.org/article/6f935b3fd4fd4f49b1ebcbe9d3070f51
Autor:
Sergei Tcyrulnikov, Joshua D. Sieber, Nitinchandra D. Patel, Kendricks S. Lao, Marisa C. Kozlowski, Soumik Biswas, Chris H. Senanayake, Nelu Grinberg, Krishnaja Duvvuri, Neil K. Garg, B. Frank Gupton, Daniel Rivalti, Jinhua J. Song, Scott Pennino, Bo Qu, Heewon Lee, Donghong A. Gao, Yongda Zhang, Hari P. R. Mangunuru, Nizar Haddad, Bryan J. Simmons, Keith R. Fandrick
Publikováno v:
ACS Catalysis. 8:10190-10209
Metal-catalyzed cross-coupling reactions are extensively employed in both academia and industry for the synthesis of biaryl derivatives for applications to both medicine and material science. Application of these methods to prepare tetra-ortho-substi
Autor:
Christian A. Malapit, Heewon Lee, Sonia Rodriguez, Hari P. R. Mangunuru, Carl A. Busacca, Chris H. Senanayake, Nathan K. Yee, Bo Qu, Nizar Haddad, Jinhua J. Song, Jonathan T. Reeves
Publikováno v:
Synthesis. 50:4435-4443
The Pd-catalyzed 3-arylation of 2-oxindoles with aryl bromides, chlorides and triflates is found to proceed using i-Pr-BI-DIME and Me2-BI-DIME ligands. The mono-arylation of 3-unsubstituted oxindoles is accomplished using a Pd2(dba)3/i-Pr-BI-DIME cat
Autor:
Joshua D. Sieber, Heewon Lee, Yongda Zhang, Sergei Tcyrulnikov, Jean-Nicolas Desrosiers, Joyce C. Leung, Nathan K. Yee, Olga V. Zatolochnaya, Kendricks S. Lao, Sonia Rodriguez, Soumik Biswas, Hari P. R. Mangunuru, Bo Qu, Nelu Grinberg, Daniel Rivalti, Chris H. Senanayake, Xiao-Jun Wang, Guisheng Li, Marisa C. Kozlowski, Nizar Haddad, Jinhua J. Song
Publikováno v:
Chemical Science. 9:4505-4510
A new class of tunable heterophosphole dimeric ligands have been designed and synthesized. These ligands have enabled the first examples of Cu-catalyzed hydrogenation of 2-substituted-1-tetralones and related heteroaryl ketones via dynamic kinetic re
Publikováno v:
RSC Advances. 7:40887-40895
Carbohydrate based small molecular gelators are important classes of compounds which can form useful soft materials with many practical applications. Although many different types of effective gelators have been reported, the rational design of a mol
Autor:
Heewon Lee, Nelu Grinberg, Nizar Haddad, Chris H. Senanayake, Nathan K. Yee, Joshua D. Sieber, Dmitry Kurouski, Nitinchandra D. Patel, Keith R. Fandrick, Jinhua J. Song, Bo Qu, Jean-Nicolas Desrosiers, Sonia Rodriguez, Hari P. R. Mangunuru
Publikováno v:
Advanced Synthesis & Catalysis. 358:3522-3527
Through a computer-guided approach, new series of monophosphine ligands were designed and developed for asymmetric Suzuki–Miyaura couplings of challenging heterocyclic substrates. Computer modeling pointed to a tunable, yet unexplored quadrant in B
Autor:
Joshua D. Sieber, Shengli Ma, Jolaine Savoie, Xudong Wei, Max Sarvestani, Dmitry Kurouski, Jean-Nicolas Desrosiers, Hari P. R. Mangunuru, Bo Qu, Heewon Lee, Nizar Haddad, Nelu Grinberg, Lalith P. Samankumara, Keith R. Fandrick, Jinhua J. Song, Nathan K. Yee, Chris H. Senanayake
Publikováno v:
Organic Letters. 18:4920-4923
An Ir-catalyzed enantioselective hydrogenation of 2-alkyl-pyridines has been developed using ligand MeO-BoQPhos. High levels of enantioselectivities up to 93:7 er were obtained. The resulting enantioenriched piperidines can be readily converted into
Autor:
Joshua D. Sieber, Bo Qu, Heewon Lee, Olga V. Zatolochnaya, Nizar Haddad, Jean-Nicolas Desrosiers, Ling Wu, Soumik Biswas, Chris H. Senanayake, Guisheng Li, Nathan K. Yee, Nelu Grinberg, Xiao-Jun Wang, Daniel R. Fandrick, Daniel Rivalti, Sonia Rodriguez, Hari P. R. Mangunuru, Shuklendu D. Karyakarte, Jinhua J. Song
Publikováno v:
Organic letters. 20(7)
Novel bidentate phosphine ligands BABIPhos featuring a biaryl bis-dihydrobenzooxaphosphole core are presented. Their synthesis was achieved via Pd-catalyzed reductive homocoupling of dihydrobenzooxaphosphole aryl triflates. An efficient route toward
Autor:
Keith R. Fandrick, Daniel Rivalti, Nizar Haddad, Marisa C. Kozlowski, Olga V. Zatolochnaya, Suttipol Radomkit, Scott Pennino, Nathan K. Yee, Keith McKellop, Dmitry Kurouski, Jean-Nicolas Desrosiers, Heewon Lee, Chris H. Senanayake, Soumik Biswas, Shuklendu D. Karyakarte, Jinhua J. Song, Bo Qu, Sonia Rodriguez, Hari P. R. Mangunuru, Sergei Tcyrulnikov, Joshua D. Sieber
Enantioselective synthesis of α-aryl and α-heteroaryl piperidines is reported. The key step is an iridium-catalyzed asymmetric hydrogenation of substituted N-benzyl pyridinium salts. High levels of enantioselectivity up to 99.3:0.7 er were obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea58d5693fceeb4c744ba3de80f4c7e0
https://europepmc.org/articles/PMC5835364/
https://europepmc.org/articles/PMC5835364/