Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hari K. K. Subramanian"'
Autor:
Bryan Leatham, Katie McNall, Hari K. K. Subramanian, Lucien Jacky, John Alvarado, Dominic Yurk, Mimi Wang, Donald C. Green, Gregory J. Tsongalis, Aditya Rajagopal, Jerrod J. Schwartz
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2221-2234 (2023)
Digital PCR (dPCR) is emerging as an ideal platform for the detection and tracking of genomic variants in cancer due to its high sensitivity and simple workflow. The growing number of clinically actionable cancer biomarkers creates a need for fast, a
Externí odkaz:
https://doaj.org/article/2f8abd2ae9464955898cc183ee988e88
Autor:
Donghyun Lim, Qingxuan Zhou, Kurt J. Cox, Benjamin K. Law, Miseon Lee, Praveen Kokkonda, Vedagopuram Sreekanth, Rajaiah Pergu, Santosh K. Chaudhary, Soumyashree A. Gangopadhyay, Basudeb Maji, Sophia Lai, Yuka Amako, David B. Thompson, Hari K. K. Subramanian, Michael F. Mesleh, Vlado Dančík, Paul A. Clemons, Bridget K. Wagner, Christina M. Woo, George M. Church, Amit Choudhary
Publikováno v:
Nat Cell Biol
The need to control the activity and fidelity of CRISPR-associated nucleases has resulted in a demand for inhibitory anti-CRISPR molecules. The small-molecule inhibitor discovery platforms available at present are not generalizable to multiple nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fc6b03b4a9c93d1ffd988021f853ba
https://doi.org/10.1038/s41556-022-01005-8
https://doi.org/10.1038/s41556-022-01005-8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2433
Artificial self-assembling RNA scaffolds can be produced from many types of RNA motifs that are rationally designed. These scaffolds are of interest as nanoscale organizers, with applications in drug delivery and synthetic cells. Here we describe des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4be2eea66eacaabecd9319bb0402899c
https://pubmed.ncbi.nlm.nih.gov/34985752
https://pubmed.ncbi.nlm.nih.gov/34985752
Autor:
Rizal F. Hariadi, Vahid Mardanlou, Leopold N. Green, Elisa Franco, Jongmin Kim, Hari K. K. Subramanian
Publikováno v:
Nature Chemistry. 11:510-520
Biological cells routinely reconfigure their shape using dynamic signalling and regulatory networks that direct self-assembly processes in time and space, through molecular components that sense, process and transmit information from the environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8de787384cc068c08877b18f5b815ca
https://doi.org/10.1038/s41557-019-0251-8
https://doi.org/10.1038/s41557-019-0251-8
Autor:
Hari K. K. Subramanian, Samuel W. Schaffter, Elisa Franco, Joanna Schneider, Rebecca Schulman, Leopold N. Green
Publikováno v:
Nucleic Acids Research
The use of proteins that bind and catalyze reactions with DNA alongside DNA nanostructures has broadened the functionality of DNA devices. DNA binding proteins have been used to specifically pattern and tune structural properties of DNA nanostructure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7971498a2329f443acd3ca7faa1d59
https://doi.org/10.1093/nar/gky283
https://doi.org/10.1093/nar/gky283
Autor:
Kimia C. Yaghoubi, Hari K. K. Subramanian, Jongmin Kim, Elisa Franco, Vahid Mardanlou, Leopold N. Green, Rizal F. Hariadi
Publikováno v:
Natural Computing. 17:183-199
We derive a coarse-grained model that captures the temporal evolution of DNA nanotube length distribution during growth experiments. The model takes into account nucleation, polymerization, joining, and fragmentation processes in the nanotube populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1fb3491e7bdfe42e51e030d34ea4f60
https://doi.org/10.1007/s11047-017-9657-7
https://doi.org/10.1007/s11047-017-9657-7
Publikováno v:
Small. 12:2689-2700
The nanoscale features of DNA have made it a useful molecule for bottom-up construction of nanomaterials, for example, two- and three-dimensional lattices, nanomachines, and nanodevices. One of the emerging applications of such DNA-based nanostructur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe901ed2b40777b4ba3f34af23c6aa54
https://doi.org/10.1002/smll.201503854
https://doi.org/10.1002/smll.201503854
Autor:
Mathias Viard, Kirill A. Afonin, Elisa Franco, Jaimie Marie Stewart, Brandon K. Roark, Hari K. K. Subramanian
Publikováno v:
Nanoscale. 8:17542-17550
RNA is a natural multifunctional polymer, and is an essential component in both complex pathways and structures within the cellular environment. For this reason, artificial self-assembling RNA nanostructures are emerging as a powerful tool with broad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f99ca1156220caa4b8281278b4b9887
https://doi.org/10.1039/c6nr05085a
https://doi.org/10.1039/c6nr05085a
Publikováno v:
Chemical Science. 11:10287-10287
Correction for ‘A universal method for sensitive and cell-free detection of CRISPR-associated nucleases’ by Kurt J. Cox et al., Chem. Sci., 2019, 10, 2653–2662, DOI: 10.1039/C8SC03426E.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f25fe5f7b15e8cee6775cbf3cf607f
https://doi.org/10.1039/d0sc90196b
https://doi.org/10.1039/d0sc90196b
Publikováno v:
Chemical Science
We report a universal assay for sensitive, cell-free detection of CRISPR-associated nucleases by coupling activity to a fluorescent transcription product.
A multitude of biological applications for CRISPR-associated (Cas) nucleases have propelle
A multitude of biological applications for CRISPR-associated (Cas) nucleases have propelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9889153caf958875a3ec6c6f4be3a0d3
https://pubmed.ncbi.nlm.nih.gov/34094293
https://pubmed.ncbi.nlm.nih.gov/34094293