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CD137L dendritic cells induce potent response against cancer-associated viruses and polarize human CD8⁺ T cells to Tc1 phenotype.

Autor: Dharmadhikari, Bhushan, Nickles, Emily, Harfuddin, Zulkarnain, Ishak, Nur Diana Binte, Zeng, Qun, Bertoletti, Antonio, Schwarz, Herbert

Publikováno v: Cancer Immunology, Immunotherapy; Jun2018, Vol. 67 Issue 6, p893-905, 13p

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CD137 and CD137L signals are main drivers of type 1, cell-mediated immune responses.

Autor: Dharmadhikari B; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Wu M; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Abdullah NS; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Rajendran S; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Ishak ND; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Nickles E; Department of Physiology, and Immunology Programme, National University of Singapore , Singapore., Harfuddin Z; Department of Physiology, and Immunology Programme, National University of Singapore, Singapore; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore., Schwarz H; Department of Physiology, and Immunology Programme, National University of Singapore, Singapore; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.

Publikováno v: Oncoimmunology [Oncoimmunology] 2015 Nov 11; Vol. 5 (4), pp. e1113367. Date of Electronic Publication: 2015 Nov 11 (Print Publication: 2016).