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Endotoxin detoxification by alkaline phosphatase in cholestatic livers

Autor: Poelstra, K, Bakker, WW, Hardonk, MJ, Meijer, DKF, Wisse, E, Knook, DL, Balabaud, C

Publikováno v: CELLS OF THE HEPATIC SINUSOID, VOL 6, 187-190
STARTPAGE=187;ENDPAGE=190;TITLE=CELLS OF THE HEPATIC SINUSOID, VOL 6

Increased expression of alkaline phosphatase (AP) in the liver is a hallmark of cholestasis but the pathophysiological role of this is not clear. We argue that deprotonation of carboxyl groups at the active site of the enzyme may be a prerequisite fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d188ff8c18de759e50f0024733d584c0
https://research.rug.nl/en/publications/09fd49d5-a92a-41af-9ee7-a40d67bddc00

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Increased epithelial cell proliferation in the colon of patients with acromegaly

Autor: Cats, A, Dullaart, RPF, Kleibeuker, JH, Kuipers, F, Sluiter, WJ, Hardonk, MJ, deVries, EGE

Publikováno v: Cancer Research, 56(3), 523-526. AMER ASSOC CANCER RESEARCH

To gain insight into the possible physiological mechanisms responsible for the increased incidence of colonic neoplasms in patients with acromegaly, a prospective cohort study was carried out in 30 patients with acromegaly. Seven patients had a newly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::526e4f3b1a3af7eca6977587f5d3455b
https://research.rug.nl/en/publications/03c741ae-b8d1-43f6-8a46-eaa10b5ee19c

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HISTOCHEMICAL AND ELECTRON-MICROSCOPIC CHARACTERIZATION OF HEPATIC MACROPHAGE SUBFRACTIONS ISOLATED FROM NORMAL AND LIPOSOMAL MURAMYL DIPEPTIDE TREATED RATS

Autor: HOEDEMAKERS, RMJ, ATMOSOERODJOBRIGGS, JE, MORSELT, HWM, DAEMEN, T, SCHERPHOF, GL, HARDONK, MJ

Publikováno v: Liver, 15(3), 113-120

Subfractions of the hepatic macrophage population, differing in cell size, were isolated from normal rats and rats treated with liposomal muramyl dipeptide (lipMDP) and analyzed histochemically and by ultrastructural peroxidase cytochemistry. The maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::433aa70f0d9576e074fc81f916375dea
https://research.rug.nl/en/publications/39ba8405-576d-4a60-877a-c718ef298b07

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EPITHELIAL-CELL PROLIFERATION IN THE SIGMOID COLON OF PATIENTS WITH ADENOMATOUS POLYPS INCREASES DURING ORAL CALCIUM SUPPLEMENTATION

Autor: KLEIBEUKER, JH, WELBERG, JWM, MULDER, NH, VANDERMEER, R, CATS, A, LIMBURG, AJ, KREUMER, WMT, HARDONK, MJ, DEVRIES, EGE

Publikováno v: British Jounal of Cancer, 67(3), 500-503. Nature Publishing Group

To study the effect of oral supplemental calcium on colonic epithelial proliferation, 17 adenomatous polyp patients received 1.5 g Ca2+ as calcium carbonate daily during 12 weeks, while on a calcium constant diet, based on the patients' habitual diet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::8116a58e3d9341397300fd3ca77b56de
https://research.rug.nl/en/publications/84e62e51-2b81-4f60-90b0-14de350d4302

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