Methuselah Flies: A Case Study In The Evolution Of Aging

Autor: Michael Robertson Rose, Hardip B Passananti, Margarida Matos

Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the spec

The effects of evolution are local: Evidence from experimental evolution in Drosophila

Autor: Adam K. Chippindale, Henrique Teotónio, Laurence D. Mueller, Michael R. Rose, John P. Phelan, Margarida Gaspar de Matos, Hardip B. Passananti

Publikováno v: Rose, MR; Passananti, HB; Chippindale, AK; Phelan, JP; Matos, M; Teotónio, H; et al.(2005). The effects of evolution are local: Evidence from experimental evolution in Drosophila. Integrative and Comparative Biology, 45(3), 486-491. doi: 10.1093/icb/45.3.486. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7dr7f2z5

One of the enduring temptations of evolutionary theory is the extrapolation from short-term to long-term, from a few species to all species. Unfortunately, the study of experimental evolution reveals that extrapolation from local to general patterns

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315140c263b0892a56aee2126b309bb3
http://www.escholarship.org/uc/item/7dr7f2z5

Reverse Evolution of Aging

Autor: Michael R. Rose, Hardip B. Passananti

Publikováno v: Methuselah Flies: A Case Study in the Evolution of Aging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a1618bce0c747b2ea075efff32a1041
https://doi.org/10.1142/9789812567222_0022

Relaxed Stress Selection in Drosophila melanogaster

Autor: Kelly A. Beckman, Michael R. Rose, Hardip B. Passananti

Publikováno v: Methuselah Flies: A Case Study in the Evolution of Aging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a56eb1500f6337408bd0a86334d9d303
https://doi.org/10.1142/9789812567222_0028

Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity

Autor: Raj Kurapati, Hardip B. Passananti, Michael R. Rose, John Tower

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences. 55(11)

RNAs for the small heat shock protein (hsp) genes hsp22 and hsp23 are induced during Drosophila aging, suggesting that these genes might have specific functions at late ages. To determine if hsp22 and hsp23 gene expression might correlate with life s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8b4ca06a223bb64418e40f47c8322d
https://pubmed.ncbi.nlm.nih.gov/11078089